PMID- 31557075
OWN - NLM
STAT- MEDLINE
DCOM- 20200302
LR  - 20221207
IS  - 1530-891X (Print)
IS  - 1530-891X (Linking)
VI  - 26
IP  - 2
DP  - 2020 Feb
TI  - CLINICAL CHARACTERISTICS OF PATIENTS WITH TYPE 2 DIABETES MELLITUS CONTINUED ON 
      ORAL ANTIDIABETES MEDICATIONS IN THE HOSPITAL.
PG  - 167-173
LID - 10.4158/EP-2018-0524 [doi]
AB  - Objective: Basal/basal-bolus insulin with discontinuation of home oral 
      antidiabetes medications (OADs) is the preferred method to achieve glycemic 
      control in many hospitalized patients. We hypothesized that a subset of patients 
      with type 2 diabetes mellitus (T2DM) can achieve an acceptable level of blood 
      sugar control without cessation of their OADs when hospitalized. Methods: A 
      retrospective chart review was conducted on patients with T2DM who were only on 
      OADs at home, admitted to Fairview Hospital, a community hospital in the 
      Cleveland Clinic Health System. We divided patients into those whose OADs were 
      continued (group 1) and those whose OADs were discontinued (group 2), with or 
      without the addition of insulin in the hospital. Blood glucose (BG) levels and 
      patient characteristics were compared. Results: There were 175 patients, 73 in 
      group 1 and 102 in group 2. The percentage of patients achieving all BG values 
      within 100 to 180 mg/dL was the same between group 1 (21.9%) and group 2 (23.8%) 
      (P = .78). Mean BG was similar between group 1 and group 2 (146.1 +/- 41.4 mg/dL 
      versus 152.1 +/- 38.9 mg/dL; P = .33), with no significant difference in terms of 
      percentage of patients with hyperglycemia or hypoglycemia. A greater proportion 
      of patients in group 1 had an uninterrupted feeding status, nonintensive care 
      unit admission and no contrast dye exposure, and a shorter length of stay. 
      Conclusion: Our study shows that patients with certain characteristics could 
      achieve an acceptable level of glycemic control without cessation of their home 
      OADs. Abbreviations: BG = blood glucose; DPP-4 = dipeptidyl dipeptidase 4; GFR = 
      glomerular filtration rate; HbA1c = hemoglobin A1c; ICU = intensive care unit; 
      LOS = length of stay; NPO = nil per os; OAD = oral antidiabetes medication; POC = 
      point of care; T2DM = type 2 diabetes mellitus.
FAU - Amir, Maryam
AU  - Amir M
FAU - Sinha, Vaishali
AU  - Sinha V
FAU - Kistangari, Gaurav
AU  - Kistangari G
FAU - Lansang, M Cecilia
AU  - Lansang MC
LA  - eng
PT  - Journal Article
DEP - 20190926
PL  - United States
TA  - Endocr Pract
JT  - Endocrine practice : official journal of the American College of Endocrinology 
      and the American Association of Clinical Endocrinologists
JID - 9607439
RN  - 0 (Blood Glucose)
RN  - 0 (Glycated Hemoglobin A)
RN  - 0 (Hypoglycemic Agents)
RN  - 0 (Insulin)
SB  - IM
MH  - Blood Glucose
MH  - *Diabetes Mellitus, Type 2
MH  - Glycated Hemoglobin
MH  - Humans
MH  - Hypoglycemic Agents
MH  - Insulin
MH  - Retrospective Studies
EDAT- 2019/09/27 06:00
MHDA- 2020/03/03 06:00
CRDT- 2019/09/27 06:00
PHST- 2019/09/27 06:00 [pubmed]
PHST- 2020/03/03 06:00 [medline]
PHST- 2019/09/27 06:00 [entrez]
AID - S1530-891X(20)35097-7 [pii]
AID - 10.4158/EP-2018-0524 [doi]
PST - ppublish
SO  - Endocr Pract. 2020 Feb;26(2):167-173. doi: 10.4158/EP-2018-0524. Epub 2019 Sep 
      26.