PMID- 3155895
OWN - NLM
STAT- MEDLINE
DCOM- 19850305
LR  - 20190622
IS  - 0002-9149 (Print)
IS  - 0002-9149 (Linking)
VI  - 55
IP  - 4
DP  - 1985 Feb 1
TI  - Clinical, angiographic, hemodynamic, perfusional and functional changes after 
      one-vessel left anterior descending coronary angioplasty.
PG  - 347-56
AB  - Percutaneous transluminal coronary angioplasty (PTCA) was successfully performed 
      in 20 patients with 1-vessel left anterior descending (LAD) coronary artery 
      disease. Exercise capacity in terms of peak workload, heart rate and systolic 
      blood pressure all increased significantly 1 week after PTCA. All patients had 
      some decrease in stenosis size and gradient. All patients except 1 had an 
      improvement in functional class. Eight of 12 patients with abnormal exercise 
      electrocardiograms before PTCA had normal electrocardiograms after the procedure. 
      Exercise thallium-201 (TI-201) myocardial perfusion images obtained in all 20 
      patients before and 1 week after PTCA were analyzed using a new computer method 
      designed to quantitate regional myocardial TI-201 distribution, redistribution 
      and clearance rate. Significant improvement in TI-201 activity was present in the 
      anterior and septal segments of the left ventricle 1 week after PTCA. This 
      increase in TI-201 uptake was associated with a significant reduction in the 
      amount of TI-201 redistribution between initial and delayed postexercise images 
      in the same regions. TI-201 clearance rate in the segments supplied by the 
      dilated vessel also improved significantly. Abnormal TI-201 lung uptake was seen 
      in 17 patients before and in 4 patients after PTCA. Exercise ejection fraction 
      response and septal wall motion also improved after PTCA of the LAD stenosis in 
      all 17 patients who had exercise radionuclide ventriculography. Improvement in 
      clinical, angiographic and hemodynamic factors as well as in global and regional 
      myocardial perfusion and function occurs after PTCA for 1-vessel LAD coronary 
      artery disease.
FAU - Okada, R D
AU  - Okada RD
FAU - Lim, Y L
AU  - Lim YL
FAU - Boucher, C A
AU  - Boucher CA
FAU - Pohost, G M
AU  - Pohost GM
FAU - Chesler, D A
AU  - Chesler DA
FAU - Block, P C
AU  - Block PC
LA  - eng
GR  - HL-21751/HL/NHLBI NIH HHS/United States
GR  - HL-26215/HL/NHLBI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Am J Cardiol
JT  - The American journal of cardiology
JID - 0207277
RN  - 0 (Radioisotopes)
RN  - AD84R52XLF (Thallium)
SB  - IM
MH  - Adult
MH  - *Angioplasty, Balloon
MH  - *Coronary Angiography
MH  - Coronary Disease/*diagnostic imaging/physiopathology/therapy
MH  - Electrocardiography
MH  - Exercise Test
MH  - Female
MH  - Follow-Up Studies
MH  - *Hemodynamics
MH  - Humans
MH  - Kinetics
MH  - Male
MH  - Middle Aged
MH  - Myocardial Contraction
MH  - Radioisotopes
MH  - Radionuclide Imaging
MH  - Stroke Volume
MH  - Thallium/metabolism
EDAT- 1985/02/01 00:00
MHDA- 1985/02/01 00:01
CRDT- 1985/02/01 00:00
PHST- 1985/02/01 00:00 [pubmed]
PHST- 1985/02/01 00:01 [medline]
PHST- 1985/02/01 00:00 [entrez]
AID - 0002-9149(85)90374-1 [pii]
AID - 10.1016/0002-9149(85)90374-1 [doi]
PST - ppublish
SO  - Am J Cardiol. 1985 Feb 1;55(4):347-56. doi: 10.1016/0002-9149(85)90374-1.