PMID- 31560571 OWN - NLM STAT- MEDLINE DCOM- 20210427 LR - 20210427 IS - 1744-5078 (Electronic) IS - 0927-3948 (Linking) VI - 28 IP - 4 DP - 2020 May 18 TI - Clinical and Demographic Features of Pediatric-Onset Behcet's Disease and Evaluation of Optical Coherence Tomography Findings. PG - 606-612 LID - 10.1080/09273948.2019.1611875 [doi] AB - PURPOSE: To evaluate the clinical characteristics, including spectral domain optical coherence tomography (SD-OCT) findings, of pediatric-onset Behcet's disease (PBD) patients. METHODS: Medical records of 23 PBD (15 males and 8 females) and 24 (15 males and 9 females) healthy subjects were evaluated retrospectively. The main outcomes were compared between PBD patients, with and without ocular involvement, and healthy subjects. RESULTS: The mean age at onset was 12.00 +/- 2.10 years. Mean follow-up period was 25.17 +/- 15.36 months (range 6-48). Retinal vasculitis was the most common ocular finding (7 patients). Most of the complications of systemic treatment were associated with long term corticosteroid therapy. There was no significant difference between the mean retinal thickness of the PBD patients and healthy controls (p > 0.05). The mean choroidal thickness was significantly increased in all measured segments of PBD patients with ocular involvement (p < 0.01). CONCLUSION: Choroidal thickness of PBD patients with ocular involvement was significantly thicker compared to the PBD patients without ocular involvement and to healthy control subjects. FAU - Balbaba, Mehmet AU - Balbaba M AD - Faculty of Medicine, Department of Ophthalmology, Firat University , Elazig, Turkey. FAU - Ulas, Fatih AU - Ulas F AUID- ORCID: 0000-0003-4468-3985 AD - Faculty of Medicine, Department of Ophthalmology, Bolu Abant Izzet Baysal University , Bolu, Turkey. FAU - Postaci, Sevinc Arzu AU - Postaci SA AD - Faculty of Medicine, Department of Ophthalmology, Firat University , Elazig, Turkey. FAU - Celiker, Ulku AU - Celiker U AD - Faculty of Medicine, Department of Ophthalmology, Firat University , Elazig, Turkey. FAU - Gurgoze, Metin Kaya AU - Gurgoze MK AD - Faculty of Medicine, Department of Pediatric Rheumatology, Firat University , Elazig, Turkey. LA - eng PT - Journal Article DEP - 20190927 PL - England TA - Ocul Immunol Inflamm JT - Ocular immunology and inflammation JID - 9312169 SB - IM MH - Adolescent MH - Behcet Syndrome/*diagnosis MH - Child MH - Choroid/*pathology MH - Female MH - Fluorescein Angiography/methods MH - Follow-Up Studies MH - Fundus Oculi MH - Humans MH - Male MH - Retina/*pathology MH - Retrospective Studies MH - Tomography, Optical Coherence/*methods OTO - NOTNLM OT - Behcet's disease OT - choroidal thickness OT - optical coherence tomography OT - pediatric-onset Behcet's disease OT - retinal thickness EDAT- 2019/09/29 06:00 MHDA- 2021/04/28 06:00 CRDT- 2019/09/28 06:00 PHST- 2019/09/29 06:00 [pubmed] PHST- 2021/04/28 06:00 [medline] PHST- 2019/09/28 06:00 [entrez] AID - 10.1080/09273948.2019.1611875 [doi] PST - ppublish SO - Ocul Immunol Inflamm. 2020 May 18;28(4):606-612. doi: 10.1080/09273948.2019.1611875. Epub 2019 Sep 27.