PMID- 31563859
OWN - NLM
STAT- MEDLINE
DCOM- 20200604
LR  - 20200604
IS  - 2212-1102 (Electronic)
IS  - 2212-1099 (Linking)
VI  - 20
DP  - 2019 Dec
TI  - Economic Cost of Severe Acute Respiratory Infection Associated to Influenza in 
      Colombian Children: A Single Setting Analysis.
PG  - 159-163
LID - S2212-1099(19)30096-2 [pii]
LID - 10.1016/j.vhri.2019.07.010 [doi]
AB  - BACKGROUND: Influenza is considered a leading public health problem because its 
      large economic burden of disease worldwide, especially in low-and middle-income 
      countries, such as Colombia. OBJECTIVE: We aimed to estimate the economic costs 
      of influenza-confirmed patients in a pediatric hospital in Cartagena, Colombia. 
      METHODS: We conducted a retrospective costing analysis. We estimated the direct 
      (direct medical and out-of-pocket expenditures) and indirect costs for 
      influenza-confirmed severe acute respiratory infection cases from a societal 
      perspective. Total economic costs were calculated adding direct medical costs, 
      out-of-pocket expenditures, and indirect costs owing to loss of productivity of 
      caregivers. Mean, median, 95% confidence interval (95% CI) and interquartile 
      range (IQR) of costs were measured. All costs are reported in USD ($1.00 = 
      COP$2000.7) RESULTS: Forty-four cases were included in the analysis: 30 had 
      influenza B, 10 influenza A and B, and 4 influenza AH1N1. Thirty patients were 
      hospitalized in the general ward, 14 went to the intensive care unit. The average 
      duration of stay was  approximately 9 days (95% CI, 6.3-11.5). The median direct medical cost 
      for hospitalized case in general ward was $743.50 (IQR $590.20-$1404.60) and in 
      intensive care unit $4669.80 (IQR $1614.60-$7801.50). The economic cost per 
      hospitalized case was $1826.10 (IQR $1343.30-$2376.50); direct medical costs 
      represented 93.8% of this cost. The median indirect cost was $82.10 (IQR 
      $41.10-$133.40) and the median out-of-pocket expenditure per case was $45.70 (IQR 
      $29.50-$64.90). CONCLUSIONS: Severe acute respiratory infection is an important 
      source of economic burden for the health system, families, and society in 
      Colombia. Seasonal influenza vaccination should be strengthened to prevent more 
      cases and save economic resources.
CI  - Copyright (c) 2019 ISPOR--The professional society for health economics and 
      outcomes research. Published by Elsevier Inc. All rights reserved.
FAU - Salcedo-Mejia, Fernando
AU  - Salcedo-Mejia F
AD  - Departamento de Analisis de Datos, ALZAK Foundation, Cartagena, Colombia.
FAU - Alvis-Zakzuk, Nelson J
AU  - Alvis-Zakzuk NJ
AD  - Departamento de Ciencias Empresariales, Universidad de la Costa-CUC, 
      Barranquilla, Colombia; Observatorio Nacional de Salud, Instituto Nacional de 
      Salud, Bogota, DC, Colombia. Electronic address: alviszakzuk@gmail.com.
FAU - Carrasquilla-Sotomayor, Maria
AU  - Carrasquilla-Sotomayor M
AD  - Departamento de Evaluaciones Economicas, ALZAK Foundation, Cartagena, Colombia.
FAU - Redondo, Hernando Pinzon
AU  - Redondo HP
AD  - Grupo de Investigacion de Infectologia Peditrica, Fundacion Hospital Infantil 
      Napoleon Franco Pareja, Universidad de Cartagena, Cartagena, Colombia.
FAU - Castaneda-Orjuela, Carlos
AU  - Castaneda-Orjuela C
AD  - Observatorio Nacional de Salud, Instituto Nacional de Salud, Bogota, DC, 
      Colombia; Grupo de Evaluacion en Epidemiologia y Salud Publica, Universidad 
      Nacional de Colombia, Bogota, DC, Colombia.
FAU - De la Hoz-Restrepo, Fernando
AU  - De la Hoz-Restrepo F
AD  - Grupo de Evaluacion en Epidemiologia y Salud Publica, Universidad Nacional de 
      Colombia, Bogota, DC, Colombia.
FAU - Alvis-Guzman, Nelson
AU  - Alvis-Guzman N
AD  - Departamento de Ciencias Empresariales, Universidad de la Costa-CUC, 
      Barranquilla, Colombia; Departamento de Economia, Universidad de Cartagena, 
      Cartagena, Colombia.
LA  - eng
PT  - Journal Article
DEP - 20190927
PL  - United States
TA  - Value Health Reg Issues
JT  - Value in health regional issues
JID - 101592642
SB  - IM
MH  - Colombia/epidemiology
MH  - Female
MH  - Health Care Costs/*statistics & numerical data
MH  - Health Expenditures/statistics & numerical data
MH  - Hospital Costs/statistics & numerical data
MH  - Humans
MH  - Infant
MH  - Influenza A Virus, H1N1 Subtype
MH  - Influenza A virus
MH  - Influenza B virus
MH  - Influenza, Human/*economics/epidemiology/etiology/virology
MH  - Length of Stay/economics/statistics & numerical data
MH  - Male
MH  - Severe Acute Respiratory Syndrome/*economics/epidemiology/etiology/virology
OTO - NOTNLM
OT  - acute respiratory infection
OT  - cost analysis
OT  - direct cost
OT  - indirect cost
OT  - out-of-pocket
EDAT- 2019/09/30 06:00
MHDA- 2020/06/05 06:00
CRDT- 2019/09/30 06:00
PHST- 2018/10/05 00:00 [received]
PHST- 2019/06/24 00:00 [revised]
PHST- 2019/07/17 00:00 [accepted]
PHST- 2019/09/30 06:00 [pubmed]
PHST- 2020/06/05 06:00 [medline]
PHST- 2019/09/30 06:00 [entrez]
AID - S2212-1099(19)30096-2 [pii]
AID - 10.1016/j.vhri.2019.07.010 [doi]
PST - ppublish
SO  - Value Health Reg Issues. 2019 Dec;20:159-163. doi: 10.1016/j.vhri.2019.07.010. 
      Epub 2019 Sep 27.