PMID- 31564272
OWN - NLM
STAT- MEDLINE
DCOM- 20200228
LR  - 20200228
IS  - 1681-7168 (Electronic)
IS  - 1022-386X (Linking)
VI  - 29
IP  - 10
DP  - 2019 Oct
TI  - Two Years Remission of Type 2 Diabetes Mellitus after Bariatric Surgery.
PG  - 967-971
LID - 10.29271/jcpsp.2019.10.967 [doi]
AB  - OBJECTIVE: To determine the influence of bariatric surgery on remission of type 2 
      diabetes mellitus (T2DM) in obese patients along with improvements in other 
      obesity-associated comorbidities. STUDY DESIGN: Observational study. PLACE AND 
      DURATION OF STUDY: Doncaster and Bassetlaw NHS Trust, UK, from August 2010 to 
      August 2018. METHODOLOGY: All the cases of bariatric surgery in obese patients 
      with T2DM who had completed 2 years of follow up were included in the study. 
      Remission of T2DM was defined as glycated hemoglobin (HbA1C) <48 mmol/mol (<6.5%) 
      or fasting blood sugar of <7.0 mmol/L, not on hypoglycemic agents 2 years after 
      having bariatric surgery. Student's t-test was used to see any difference in 
      baseline HbA1C, BMI, percentage of weight loss, and duration of diabetes between 
      remitters and non-remitters. RESULTS: Two years follow-up data after bariatric 
      surgery for remission of T2DM or otherwise was available for (n=121) patients. 
      Majority (70.2%, n=85) were females and (29.8%, n=36) were males. Mean age was 
      48.21 +/-9.77 years. Eightythree (68.6%) patients achieved remission of T2DM at 2 
      years and 31.4% (n=38) did not. Remission of other comorbidities was 33.3% (n=53 
      out of 159) for hypertension (HTN), 50.8% (n=60 out of 118) for dyslipidemia, 
      67.2% (n=43 out of 64) for obstructive sleep apnea (OSA), 52.1% (n=37 out of 71) 
      for gastro esophageal reflux disease (GERD), 25.7% (n=18 out of 70) for asthma, 
      and 23.3% (n=24 out of 103) for depression. CONCLUSION: Bariatric surgery 
      effectively achieves remission of T2DM and other obesity associated 
      comorbidities.
FAU - Wazir, Nauman
AU  - Wazir N
AD  - Department of Diabetes and Endocrine, Doncaster Royal Infirmary and Bassetlaw 
      Teaching Hospitals, Doncaster DN2 5LT, UK.
FAU - Arshad, Muhammad Fahad
AU  - Arshad MF
AD  - Department of Diabetes and Endocrine, Sheffield Teaching Hospitals, Sheffield, 
      UK.
FAU - Finney, John
AU  - Finney J
AD  - Department of Nutrition and Dietics, Doncaster Royal Infirmary and Bassetlaw 
      Teaching Hospitals, Doncaster DN2 5LT, UK.
FAU - Kirk, Katie
AU  - Kirk K
AD  - Department of Surgery, Doncaster Royal Infirmary and Bassetlaw Teaching 
      Hospitals, Doncaster DN2 5LT, UK.
FAU - Dewan, Shivani
AU  - Dewan S
AD  - Department of Diabetes and Endocrine, Doncaster Royal Infirmary and Bassetlaw 
      Teaching Hospitals, Doncaster DN2 5LT, UK.
LA  - eng
PT  - Journal Article
PT  - Observational Study
PL  - Pakistan
TA  - J Coll Physicians Surg Pak
JT  - Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
JID - 9606447
RN  - 0 (Biomarkers)
SB  - IM
MH  - *Bariatric Surgery
MH  - Biomarkers/blood
MH  - Diabetes Mellitus, Type 2/*prevention & control
MH  - England
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Obesity, Morbid/*surgery
EDAT- 2019/10/01 06:00
MHDA- 2020/02/29 06:00
CRDT- 2019/10/01 06:00
PHST- 2018/11/06 00:00 [received]
PHST- 2019/04/11 00:00 [accepted]
PHST- 2019/10/01 06:00 [entrez]
PHST- 2019/10/01 06:00 [pubmed]
PHST- 2020/02/29 06:00 [medline]
AID - 040579197 [pii]
AID - 10.29271/jcpsp.2019.10.967 [doi]
PST - ppublish
SO  - J Coll Physicians Surg Pak. 2019 Oct;29(10):967-971. doi: 
      10.29271/jcpsp.2019.10.967.