PMID- 31569970
OWN - NLM
STAT- MEDLINE
DCOM- 20211025
LR  - 20211025
IS  - 1942-7522 (Electronic)
IS  - 0145-5613 (Linking)
VI  - 100
IP  - 5
DP  - 2021 Jun
TI  - The Impact of Serum 25-Hydroxyvitamin D3 Levels on Allergic Rhinitis.
PG  - NP236-NP241
LID - 10.1177/0145561319874310 [doi]
AB  - We aimed to clarify the relation between allergic rhinitis and the serum levels 
      of 25-hydroxivitamin D in the adult population. The study group consisted of 86 
      patients with allergic rhinitis who were diagnosed with the help of history of 
      allergy, positive signs for allergy, blood samples, and positive skin prick 
      tests; while the control group included 43 age- and sex-matched healthy 
      volunteers with negative skin prick tests. The demographic data, medical history, 
      findings in the physical examinations, serum levels of total immunoglobulin E 
      (IgE) and 25-hydroxyvitamin D, and skin prick test results of the groups were 
      noted. A total of 129 patients fulfilling the necessary criteria were enrolled. 
      The median serum 25-hydroxyvitamin D levels in the study group were significantly 
      lower compared to the control group (P = .014). In the study group, median serum 
      vitamin D levels were significantly higher in men, compared to women (P = .03). 
      There was a significant negative correlation between IgE and vitamin D levels in 
      the allergic rhinitis group (P = .028, r = -0.246). This study showed that 
      patients with allergic rhinitis might be more vulnerable to have lower serum 
      levels of vitamin D. Thus, vitamin D supplementation as an adjunctive therapy may 
      be considered in those patients.
FAU - Coban, Kubra
AU  - Coban K
AUID- ORCID: 0000-0002-4633-0983
AD  - 63994Baskent University Medical Faculty, Otorhinolaryngology Department, Ankara, 
      Turkey.
FAU - Oz, Isilay
AU  - Oz I
AD  - 63994Baskent University Medical Faculty, Otorhinolaryngology Department, Ankara, 
      Turkey.
FAU - Topcu, Deniz Ilhan
AU  - Topcu DI
AD  - 63994Baskent University Medical Faculty, Biochemistry Department, Ankara, Turkey.
FAU - Aydin, Erdinc
AU  - Aydin E
AD  - 63994Baskent University Medical Faculty, Otorhinolaryngology Department, Ankara, 
      Turkey.
LA  - eng
PT  - Journal Article
DEP - 20190930
PL  - United States
TA  - Ear Nose Throat J
JT  - Ear, nose, & throat journal
JID - 7701817
RN  - 37341-29-0 (Immunoglobulin E)
RN  - P6YZ13C99Q (Calcifediol)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Calcifediol/*blood/immunology
MH  - Case-Control Studies
MH  - Female
MH  - Humans
MH  - Immunoglobulin E/blood
MH  - Male
MH  - Middle Aged
MH  - Rhinitis, Allergic/*blood/immunology
MH  - Skin Tests
MH  - Vitamin D Deficiency/*immunology
MH  - Young Adult
OTO - NOTNLM
OT  - allergic rhinitis
OT  - immunoglobulin E
OT  - vitamin D
EDAT- 2019/10/02 06:00
MHDA- 2021/10/26 06:00
CRDT- 2019/10/02 06:00
PHST- 2019/10/02 06:00 [pubmed]
PHST- 2021/10/26 06:00 [medline]
PHST- 2019/10/02 06:00 [entrez]
AID - 10.1177/0145561319874310 [doi]
PST - ppublish
SO  - Ear Nose Throat J. 2021 Jun;100(5):NP236-NP241. doi: 10.1177/0145561319874310. 
      Epub 2019 Sep 30.