PMID- 31572700
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231104
IS  - 2296-2565 (Print)
IS  - 2296-2565 (Electronic)
IS  - 2296-2565 (Linking)
VI  - 7
DP  - 2019
TI  - Analytical Study of Donor's Milk Bank Macronutrients by Infrared Spectroscopy. 
      Correlations With Clinic-Metabolic Profile of 100 Donors.
PG  - 234
LID - 10.3389/fpubh.2019.00234 [doi]
LID - 234
AB  - For its specific qualitative characteristics human donor milk (DM) is the main 
      alternative to preterm infants nutrition and growing. How several studies suggest 
      child's physical and mental development is influenced by breastfeeding that 
      prevents the necrotizing enterocolitis (NEC), retinopathy of prematurity (ROP), 
      and sepsis common in preterm newborns. Our research was conducted in NICU's Human 
      Milk Bank (HMB) "Allattiamolavita." Our study was based on macronutrients 
      analysis (MA) of 100 DM samples taken until 10 days since childbirth and analyzed 
      by spectroscopic infrared innovative method (MIRIS). This is a specific method to 
      analyse fat (F), crude proteins (CP), true proteins (TP), carbohydrate (CHO), and 
      total solids (TS). We also analyzed the 100 donors' clinic-metabolic profile by 
      blood tests (PMT). Both data was collected between September 2015 and February 
      2018. The research was structured in two parts. In the first part we compared PMT 
      with qualitative and quantitative characteristics of MA while in the second one 
      we studied every DM macronutrient finding furthermore possible relations between 
      them. Statistical Package for Social Sciences (SPSS-IBM 24) was used to compare 
      data and reporting coefficient of determination using Spearman's Rho and 
      Kendall's Tau. We also analyzed samples using Kolmogorov-Smirnov test, Student 
      T-test, ANOVA, Whitney U-test, and chi-square test. Statistically significant 
      correlations were noted between maternal serum proteins and CP-TP of DM. The 
      research showed also significant correlations between azotaemia and TP and an 
      inverse correlation between serum creatinine and CP. No statistically significant 
      correlation was observed between donors' glycaemia and CHO. Mineral 
      concentrations of DM emerged independent of blood minerals (P, Ca, Fe, Na). We 
      also calculated a normal range for individual macronutrient of human transitional 
      milk (TM) that was not established in literature yet. Our experience allowed us 
      to underline that human milk is a privileged site compared to donors' clinical 
      and metabolic disorders. Our analysis showed the major role of the HMB to provide 
      DM to improve clinical status, growing, and neurocognitive short and long term 
      outcome of preterm infants.
CI  - Copyright (c) 2019 Sbrizzi, Quitadamo, Ravida, Palumbo, Cristalli and 
      Pettoello-Mantovani.
FAU - Sbrizzi, Stefania
AU  - Sbrizzi S
AD  - NICU, Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy.
FAU - Quitadamo, Pasqua Anna
AU  - Quitadamo PA
AD  - NICU, Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy.
FAU - Ravida, Domenico
AU  - Ravida D
AD  - NICU, Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy.
FAU - Palumbo, Giuseppina
AU  - Palumbo G
AD  - NICU, Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy.
FAU - Cristalli, Pier Paolo
AU  - Cristalli PP
AD  - NICU, Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy.
FAU - Pettoello-Mantovani, Massimo
AU  - Pettoello-Mantovani M
AD  - NICU, Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy.
LA  - eng
PT  - Journal Article
DEP - 20190912
PL  - Switzerland
TA  - Front Public Health
JT  - Frontiers in public health
JID - 101616579
PMC - PMC6752055
OTO - NOTNLM
OT  - breast milk
OT  - clinic-metabolic profile of donors
OT  - donor human milk
OT  - human milk bank
OT  - infrared spectroscopy
OT  - macronutrients human milk
OT  - preterm newborns
EDAT- 2019/10/02 06:00
MHDA- 2019/10/02 06:01
PMCR- 2019/09/12
CRDT- 2019/10/02 06:00
PHST- 2018/07/07 00:00 [received]
PHST- 2019/08/02 00:00 [accepted]
PHST- 2019/10/02 06:00 [entrez]
PHST- 2019/10/02 06:00 [pubmed]
PHST- 2019/10/02 06:01 [medline]
PHST- 2019/09/12 00:00 [pmc-release]
AID - 10.3389/fpubh.2019.00234 [doi]
PST - epublish
SO  - Front Public Health. 2019 Sep 12;7:234. doi: 10.3389/fpubh.2019.00234. 
      eCollection 2019.