PMID- 31581196
OWN - NLM
STAT- MEDLINE
DCOM- 20200311
LR  - 20200311
IS  - 1932-6203 (Electronic)
IS  - 1932-6203 (Linking)
VI  - 14
IP  - 10
DP  - 2019
TI  - Cardiac output measurements via echocardiography versus thermodilution: A 
      systematic review and meta-analysis.
PG  - e0222105
LID - 10.1371/journal.pone.0222105 [doi]
LID - e0222105
AB  - Echocardiography, as a noninvasive hemodynamic evaluation technique, is 
      frequently used in critically ill patients. Different opinions exist regarding 
      whether it can be interchanged with traditional invasive means, such as the 
      pulmonary artery catheter thermodilution (TD) technique. This systematic review 
      aimed to analyze the consistency and interchangeability of cardiac output 
      measurements by ultrasound (US) and TD. Five electronic databases were searched 
      for studies including clinical trials conducted up to June 2019 in which 
      patients' cardiac output was measured by ultrasound techniques (echocardiography) 
      and TD. The methodological quality of the included studies was evaluated by two 
      independent reviewers who used the Quality Assessment of Diagnostic Accuracy 
      Studies-2 (QUADAS-2), which was tailored according to our systematic review in 
      Review Manager 5.3. A total of 68 studies with 1996 patients were identified as 
      eligible. Meta-analysis and subgroup analysis were used to compare the cardiac 
      output (CO) measured using the different types of echocardiography and different 
      sites of Doppler use with TD. No significant differences were found between US 
      and TD (random effects model: mean difference [MD], -0.14; 95% confidence 
      interval, -0.30 to 0.02; P = 0.08). No significant differences were observed in 
      the subgroup analyses using different types of echocardiography and different 
      sites except for ascending aorta (AA) (random effects model: mean difference 
      [MD], -0.37; 95% confidence interval, -0.74 to -0.01; P = 0.05) of Doppler use. 
      The median of bias and limits of agreement were -0.12 and +/-0.94 L/min, 
      respectively; the median of correlation coefficient was 0.827 (range, 
      0.140-0.998). Although the difference in CO between echocardiography by different 
      types or sites and TD was not entirely consistent, the overall effect of 
      meta-analysis showed that no significant differences were observed between US and 
      TD. The techniques may be interchangeable under certain conditions.
FAU - Zhang, Yun
AU  - Zhang Y
AD  - Department of Emergency Medicine, Wuxi People's Hospital Affiliated to Nanjing 
      Medical University, Wuxi, Jiangsu, China.
FAU - Wang, Yan
AU  - Wang Y
AD  - Education Department, Wuxi People's Hospital Affiliated to Nanjing Medical 
      University, Wuxi, Jiangsu, China.
FAU - Shi, Jing
AU  - Shi J
AD  - Department of Emergency Medicine, Wuxi People's Hospital Affiliated to Nanjing 
      Medical University, Wuxi, Jiangsu, China.
FAU - Hua, Zhiqiang
AU  - Hua Z
AD  - Department of Emergency Medicine, Wuxi People's Hospital Affiliated to Nanjing 
      Medical University, Wuxi, Jiangsu, China.
FAU - Xu, Jinyu
AU  - Xu J
AUID- ORCID: 0000-0001-7313-5502
AD  - Department of Emergency Medicine, Wuxi People's Hospital Affiliated to Nanjing 
      Medical University, Wuxi, Jiangsu, China.
LA  - eng
SI  - Dryad/10.5061/dryad.6tr059p
PT  - Journal Article
PT  - Meta-Analysis
PT  - Research Support, Non-U.S. Gov't
PT  - Systematic Review
DEP - 20191003
PL  - United States
TA  - PLoS One
JT  - PloS one
JID - 101285081
SB  - IM
MH  - Cardiac Output/*physiology
MH  - *Echocardiography
MH  - Echocardiography, Doppler
MH  - Humans
MH  - Publication Bias
MH  - Regression Analysis
MH  - Risk
MH  - *Thermodilution
PMC - PMC6776392
COIS- The authors have declared that no competing interests exist.
EDAT- 2019/10/04 06:00
MHDA- 2020/03/12 06:00
PMCR- 2019/10/03
CRDT- 2019/10/04 06:00
PHST- 2019/03/07 00:00 [received]
PHST- 2019/08/21 00:00 [accepted]
PHST- 2019/10/04 06:00 [entrez]
PHST- 2019/10/04 06:00 [pubmed]
PHST- 2020/03/12 06:00 [medline]
PHST- 2019/10/03 00:00 [pmc-release]
AID - PONE-D-19-06733 [pii]
AID - 10.1371/journal.pone.0222105 [doi]
PST - epublish
SO  - PLoS One. 2019 Oct 3;14(10):e0222105. doi: 10.1371/journal.pone.0222105. 
      eCollection 2019.