PMID- 31587543 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220410 IS - 2093-0879 (Print) IS - 2093-0887 (Electronic) IS - 2093-0879 (Linking) VI - 25 IP - 4 DP - 2019 Oct 30 TI - Elevated Intrabolus Pressure Predicts Abnormal Timed Barium Esophagram in Esophagogastric Junction Outflow Obstruction. PG - 521-524 LID - 10.5056/jnm19025 [doi] AB - BACKGROUND/AIMS: Timed barium esophagram (TBE) is used the classification of esophageal motility disorders and assessing esophageal function. Currently, there are no published studies examining the relationship between high-resolution manometry and TBE in patients with esophagogastric junction outflow obstruction (EGJOO). This study seeks to evaluate this relationship and identify manometric variables that may indicate further evaluation using TBE. METHODS: Retrospective review of medical records identified patients with a diagnosis of EGJOO per the Chicago classification version 3.0. TBE was performed using standard protocol. Patients were divided into 2 groups based on complete emptying or persistence of standing barium column at 5 minutes. RESULTS: Eleven patients were identified with EGJOO who underwent both high-resolution manometry and TBE within 3 months. Five patients had no standing barium column at 5 minutes, while 6 patients had a persistent barium column. Mean age of each group was 54.0 years and 57.8 years, respectively. Patients with abnormal TBE were found to have significantly elevated intrabolus pressure (IBP) compared with patients who had a normal TBE. CONCLUSIONS: In our study, we found significant differences in IBP between these patient groups. These findings suggest that patients with EGJOO and elevated IBP may prompt further clinical evaluation with TBE in order to clarify clinical diagnosis and guide therapeutic intervention. FAU - Hoscheit, Matthew AU - Hoscheit M AD - Departments of Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH, USA. FAU - Gabbard, Scott AU - Gabbard S AD - Departments of Gastroenterology, Cleveland Clinic Foundation, Cleveland, OH, USA. LA - eng PT - Journal Article PL - Korea (South) TA - J Neurogastroenterol Motil JT - Journal of neurogastroenterology and motility JID - 101530189 PMC - PMC6786449 OTO - NOTNLM OT - Chicago OT - Esophageal motility disorders OT - Gastrointestinal transit OT - Humans OT - Manometry COIS- Conflicts of interest: None. EDAT- 2019/10/08 06:00 MHDA- 2019/10/08 06:01 PMCR- 2019/10/01 CRDT- 2019/10/08 06:00 PHST- 2019/02/12 00:00 [received] PHST- 2019/07/20 00:00 [accepted] PHST- 2019/10/08 06:00 [entrez] PHST- 2019/10/08 06:00 [pubmed] PHST- 2019/10/08 06:01 [medline] PHST- 2019/10/01 00:00 [pmc-release] AID - jnm19025 [pii] AID - jnm-25-521 [pii] AID - 10.5056/jnm19025 [doi] PST - ppublish SO - J Neurogastroenterol Motil. 2019 Oct 30;25(4):521-524. doi: 10.5056/jnm19025.