PMID- 31587580
OWN - NLM
STAT- MEDLINE
DCOM- 20191105
LR  - 20191105
IS  - 1788-6120 (Electronic)
IS  - 0030-6002 (Linking)
VI  - 160
IP  - 41
DP  - 2019 Oct
TI  - [Community-acquired bacterial infections among type 2 diabetic and non-diabetic 
      patients hospitalized on a general medical ward: a clinical comparison].
PG  - 1623-1632
LID - 10.1556/650.2019.31508 [doi]
AB  - Introduction: Previous data showed bacterial infections among diabetic patients 
      to be more serious and frequent, with higher mortality rates in comparison with 
      non-diabetics. Recent investigations, however, are contradictory. Aim: The goal 
      of our prospective, observational study was to compare patients hospitalized on a 
      general medical ward due to community-acquired bacterial infections with type 2 
      diabetes mellitus (T2DM) to those of non-diabetics (K) by 1) infection 
      localization, 2) spectrum of pathogens, 3) three-month mortality rates. Method: 
      Patients were consecutively involved (T2DM: n = 205, K: n = 202). We 
      characterized the infections, clinical parameters, mortalities of the two groups, 
      and matched them to international data. Results: No difference regarding clinical 
      details of the groups were found except for glycemic parameters and BMI. In the 
      T2DM group the skin- and soft tissue- (37.1%), in the K patients respiratory 
      infections (37.1%) were the most common, followed by urinary ones (31.2% and 
      31.7%, respectively). Skin- and soft tissue infection incidence among T2DM 
      subjects were higher compared to international results (37.1% vs. 16%). 
      Co-presence of Gram positive and Gram negative bacteria in the skin- and soft 
      tissue infections (23/76 vs. 5/46, p = 0.0149), and polymicrobial origin in the 
      urinary tract infections (34.0% vs. 15.1%, p = 0.0335) were found to be more 
      frequent in T2DM than in K. No difference regarding mortality rates were 
      detected. In T2DM the skin- and soft tissue while in the K group the respiratory 
      infections had the most death counts. Conclusions: We found higher rates of skin- 
      and soft tissue infections among T2DM patients hospitalized on a general medical 
      ward compared to international data. In total we did not find difference 
      regarding three-month mortality between the groups. Our results highlight the 
      importance of primary prevention and shows its inadequacy concerning skin and 
      soft tissue infections among type 2 diabetics in Hungary. Orv Hetil. 2019; 
      160(41): 1623-1632.
FAU - Barkai, Laszlo Jozsef
AU  - Barkai LJ
AD  - III. Belgyogyaszati Klinika, Semmelweis Egyetem, Altalanos Orvostudomanyi Kar 
      Budapest, Ulloi ut 26., 1085.
FAU - Sipter, Emese
AU  - Sipter E
AD  - III. Belgyogyaszati Klinika, Semmelweis Egyetem, Altalanos Orvostudomanyi Kar 
      Budapest, Ulloi ut 26., 1085.
AD  - Surgossegi Centrum, Magyar Honvedseg Egeszsegugyi Kozpont Budapest.
FAU - Csuka, Dorottya
AU  - Csuka D
AD  - III. Belgyogyaszati Klinika, Semmelweis Egyetem, Altalanos Orvostudomanyi Kar 
      Budapest, Ulloi ut 26., 1085.
FAU - Balo, Timea
AU  - Balo T
AD  - III. Belgyogyaszati Klinika, Semmelweis Egyetem, Altalanos Orvostudomanyi Kar 
      Budapest, Ulloi ut 26., 1085.
FAU - Nebenfuhrer, Zsuzsa
AU  - Nebenfuhrer Z
AD  - III. Belgyogyaszati Klinika, Semmelweis Egyetem, Altalanos Orvostudomanyi Kar 
      Budapest, Ulloi ut 26., 1085.
FAU - Mathe, Andras
AU  - Mathe A
AD  - Pest Megyei Flor Ferenc Korhaz Kistarcsa.
FAU - Karadi, Istvan
AU  - Karadi I
AD  - III. Belgyogyaszati Klinika, Semmelweis Egyetem, Altalanos Orvostudomanyi Kar 
      Budapest, Ulloi ut 26., 1085.
FAU - Panczel, Pal
AU  - Panczel P
AD  - III. Belgyogyaszati Klinika, Semmelweis Egyetem, Altalanos Orvostudomanyi Kar 
      Budapest, Ulloi ut 26., 1085.
FAU - Prohaszka, Zoltan
AU  - Prohaszka Z
AD  - III. Belgyogyaszati Klinika, Semmelweis Egyetem, Altalanos Orvostudomanyi Kar 
      Budapest, Ulloi ut 26., 1085.
FAU - Hosszufalusi, Nora
AU  - Hosszufalusi N
AD  - III. Belgyogyaszati Klinika, Semmelweis Egyetem, Altalanos Orvostudomanyi Kar 
      Budapest, Ulloi ut 26., 1085.
LA  - hun
PT  - Comparative Study
PT  - Journal Article
PT  - Observational Study
TT  - 2-es tipusu diabetesesek es nem cukorbetegek teruleten szerzett, belgyogyaszati 
      osztalyos felvetelt igenylo bakterialis infekcioinak klinikai osszehasonlitasa.
PL  - Hungary
TA  - Orv Hetil
JT  - Orvosi hetilap
JID - 0376412
SB  - IM
MH  - Adult
MH  - Aged
MH  - Bacterial Infections/*diagnosis/epidemiology
MH  - Community-Acquired Infections/epidemiology/*microbiology
MH  - Diabetes Mellitus, Type 2/*complications/microbiology
MH  - Female
MH  - Gram-Negative Bacteria/*isolation & purification
MH  - Gram-Positive Bacteria/*isolation & purification
MH  - Humans
MH  - Hungary/epidemiology
MH  - Male
MH  - Middle Aged
MH  - Prospective Studies
MH  - Soft Tissue Infections/epidemiology/*microbiology
MH  - Urinary Tract Infections/epidemiology/*microbiology
OTO - NOTNLM
OT  - 2-es tipusu cukorbetegseg
OT  - bacterial infections
OT  - bakterialis fertozesek
OT  - bor-es lagyresz-fertozesek
OT  - community-acquired infection
OT  - halalozas
OT  - mortality
OT  - skin and soft tissue infections
OT  - teruleten szerzett fertozesek
OT  - type 2 diabetes mellitus
EDAT- 2019/10/08 06:00
MHDA- 2019/11/07 06:00
CRDT- 2019/10/08 06:00
PHST- 2019/10/08 06:00 [entrez]
PHST- 2019/10/08 06:00 [pubmed]
PHST- 2019/11/07 06:00 [medline]
AID - 10.1556/650.2019.31508 [doi]
PST - ppublish
SO  - Orv Hetil. 2019 Oct;160(41):1623-1632. doi: 10.1556/650.2019.31508.