PMID- 31597487
OWN - NLM
STAT- MEDLINE
DCOM- 20210304
LR  - 20220420
IS  - 1365-2931 (Electronic)
IS  - 1364-5706 (Linking)
VI  - 30
IP  - 1
DP  - 2021 Feb
TI  - Computer modeling and in vitro experimental study of water-cooled microwave 
      ablation array.
PG  - 12-20
LID - 10.1080/13645706.2019.1674878 [doi]
AB  - INTRODUCTION: Microwaves (MWs) quickly deliver relatively high temperatures into 
      tumors and cover a large ablation zone. We present a research protocol for using 
      water-cooled double-needle MW ablation arrays for tumor ablation here. MATERIAL 
      AND METHODS: Our research program includes computer modeling, tissue-mimicking 
      phantom experiments, and in vitro swine liver experiments. The computer modeling 
      is based on the finite element method (FEM) to evaluate ablation temperature 
      distributions. In tissue-mimicking phantom and in vitro swine liver ablation 
      experiments, the performances of the new device and the single-needle MW device 
      currently used in clinical practice are compared. RESULTS: FEM shows that the 
      maximum transverse ablation diameter (MTAD) is 4.2 cm at 100 W output and 300 s 
      (assessed at the 50  degrees C isotherm). In the tissue-mimicking phantom, the MTDA is 
      2.6 cm at 50 W and 300 s in single-needle MW ablation, and 4 cm in double needle 
      MW ablation array. In in vitro swine liver experiments, the MTAD is 
      2.820 +/- 0.127 cm at 100 W and 300 s in single-needle MW ablation, and 
      3.847 +/- 0.103 cm in MW ablation array. CONCLUSION: A new type of water-cooled MW 
      ablation array is designed and tested, and has potential advantages over 
      currently used devices.
FAU - Chen, Dui-Dui
AU  - Chen DD
AUID- ORCID: 0000-0003-3722-713X
AD  - Department of General Surgery, Renmin Hospital of Wuhan University, Wuhan 
      University, Wuhan, China.
FAU - Du, Yu-Xin
AU  - Du YX
AD  - School of Electronic Information and Communications, Huazhong University of 
      Science and Technology, Wuhan, China.
FAU - Chen, Zu-Bing
AU  - Chen ZB
AD  - Department of General Surgery, Renmin Hospital of Wuhan University, Wuhan 
      University, Wuhan, China.
FAU - Lang, Liang
AU  - Lang L
AD  - School of Electronic Information and Communications, Huazhong University of 
      Science and Technology, Wuhan, China.
AD  - National Key Laboratory of Science and Technology on Multi-Spectral Information 
      Processing, Huazhong University of Science and Technology, Wuhan, China.
FAU - Ye, Zi
AU  - Ye Z
AD  - Department of General Surgery, Renmin Hospital of Wuhan University, Wuhan 
      University, Wuhan, China.
FAU - Yang, Qiang
AU  - Yang Q
AD  - Department of General Surgery, Renmin Hospital of Wuhan University, Wuhan 
      University, Wuhan, China.
FAU - Shen, Shi-Qiang
AU  - Shen SQ
AD  - Department of General Surgery, Renmin Hospital of Wuhan University, Wuhan 
      University, Wuhan, China.
FAU - Lei, Zhen-Yu
AU  - Lei ZY
AD  - Department of General Surgery, Renmin Hospital of Wuhan University, Wuhan 
      University, Wuhan, China.
FAU - Zhang, Si-Qi
AU  - Zhang SQ
AD  - Department of General Surgery, Renmin Hospital of Wuhan University, Wuhan 
      University, Wuhan, China.
LA  - eng
PT  - Journal Article
DEP - 20191010
PL  - England
TA  - Minim Invasive Ther Allied Technol
JT  - Minimally invasive therapy & allied technologies : MITAT : official journal of 
      the Society for Minimally Invasive Therapy
JID - 9612996
RN  - 059QF0KO0R (Water)
SB  - IM
MH  - Animals
MH  - *Catheter Ablation
MH  - Computers
MH  - Liver/surgery
MH  - *Microwaves
MH  - Swine
MH  - Water
OTO - NOTNLM
OT  - Finite-element method (FEM)
OT  - microwave ablation
OT  - microwave ablation device
OT  - tissue-mimicking phantom
EDAT- 2019/10/11 06:00
MHDA- 2021/03/05 06:00
CRDT- 2019/10/11 06:00
PHST- 2019/10/11 06:00 [pubmed]
PHST- 2021/03/05 06:00 [medline]
PHST- 2019/10/11 06:00 [entrez]
AID - 10.1080/13645706.2019.1674878 [doi]
PST - ppublish
SO  - Minim Invasive Ther Allied Technol. 2021 Feb;30(1):12-20. doi: 
      10.1080/13645706.2019.1674878. Epub 2019 Oct 10.