PMID- 31600985 OWN - NLM STAT- MEDLINE DCOM- 20200413 LR - 20200413 IS - 1648-9144 (Electronic) IS - 1010-660X (Print) IS - 1010-660X (Linking) VI - 55 IP - 10 DP - 2019 Oct 9 TI - Reinforced Olive Pate as a Source of Antioxidants with Positive Effects on Young Smokers. LID - 10.3390/medicina55100680 [doi] LID - 680 AB - Background and objectives: Olive pate (OP) is an olive-derived product with potentially beneficial effects on human health due to the presence of natural antioxidants. The present dietary supplementation study aimed to evaluate the effects on blood antioxidant levels of an olive pate reinforced with natural antioxidants (ROP) recovered from olive mill waste. Materials and methods: Ninety-eight healthy volunteers (M = 54, 55%, age 18-25) were divided into two groups: A (n = 49), practicing three or more days of physical activity a week, and B (n = 49), practicing less than two. Each group was split into two subgroups, receiving dietary supplementation with OP or ROP. The status of smoker was also recorded, and a biological antioxidant potential (BAP) test was performed on each subject. Results: The BAP values increased with both OP (n = 30) and ROP (n = 68) but ROP supplementation showed higher increments (736.9 mumol/L) than OP (339.6). The increment was significantly higher for smokers (n = 15), 1122.9 vs. non-smokers (n = 53), 635.7, with values in percent of baseline, respectively, 34.6% and 16.2% (P < 0.01). Conclusions: The ROP nutritional supplementation appears useful to increase antioxidant activity, with better effect in smokers; further studies should confirm the finding and investigate its biological bases. FAU - Cavallo, Pierpaolo AU - Cavallo P AD - Universita di Salerno, Via Giovanni Paolo II, 132, 84084 Fisciano (SA), Italy. pcavallo@unisa.it. AD - ISC-CNR, Piazzale Aldo Moro 5, 00185 Rome, Italy. pcavallo@unisa.it. FAU - Vinale, Francesco AU - Vinale F AD - Universita di Napoli "Federico II", Via Universita, 96, 80055 Portici (NA), Italy. frvinale@unina.it. FAU - Sepe, Immacolata AU - Sepe I AD - Diagnostica Cavallo-Centro Ricerca, Via C. Calo', 2, 84123 Salerno, Italy. immasepe@gmail.com. FAU - Galasso, Gennaro AU - Galasso G AD - Universita di Salerno, Via Giovanni Paolo II, 132, 84084 Fisciano (SA), Italy. ggalasso@unisa.it. FAU - Fedele, Francesca Luisa AU - Fedele FL AD - Linfa Scarl, Via Ferrante Imparato 27/29, 80100 Napoli, Italy. francalisa@yahoo.com. FAU - Sicari, Andrea AU - Sicari A AD - Linfa Scarl, Via Ferrante Imparato 27/29, 80100 Napoli, Italy. andrea@laboratoriolinfa.it. FAU - Zito, Loredana AU - Zito L AD - Santa Rita Srl, Via Zona Industriale, 89900 Vibo Valentia, Italy. lo.zito987@gmail.com. FAU - Lorito, Matteo AU - Lorito M AD - Universita di Napoli "Federico II", Via Universita, 96, 80055 Portici (NA), Italy. lorito@unina.it. LA - eng GR - Linfa 03PE_00026_1/Ministero dell'Istruzione, dell'Universita e della Ricerca/ GR - Marea 03PE_00106/Ministero dell'Istruzione, dell'Universita e della Ricerca/ PT - Journal Article DEP - 20191009 PL - Switzerland TA - Medicina (Kaunas) JT - Medicina (Kaunas, Lithuania) JID - 9425208 RN - 0 (Antioxidants) SB - IM MH - Adolescent MH - Adult MH - Antioxidants/metabolism/*therapeutic use MH - Cigarette Smoking/adverse effects/*metabolism/physiopathology MH - Female MH - Humans MH - Male MH - Olea/*metabolism PMC - PMC6843643 OTO - NOTNLM OT - antioxidants OT - functional foods OT - nutrition OT - olive derived foods OT - olive oil OT - smokers COIS- The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results. EDAT- 2019/10/12 06:00 MHDA- 2020/04/14 06:00 PMCR- 2019/10/09 CRDT- 2019/10/12 06:00 PHST- 2019/08/30 00:00 [received] PHST- 2019/09/26 00:00 [revised] PHST- 2019/10/07 00:00 [accepted] PHST- 2019/10/12 06:00 [entrez] PHST- 2019/10/12 06:00 [pubmed] PHST- 2020/04/14 06:00 [medline] PHST- 2019/10/09 00:00 [pmc-release] AID - medicina55100680 [pii] AID - medicina-55-00680 [pii] AID - 10.3390/medicina55100680 [doi] PST - epublish SO - Medicina (Kaunas). 2019 Oct 9;55(10):680. doi: 10.3390/medicina55100680.