PMID- 31607323
OWN - NLM
STAT- MEDLINE
DCOM- 20191114
LR  - 20200108
IS  - 1009-2137 (Print)
IS  - 1009-2137 (Linking)
VI  - 27
IP  - 5
DP  - 2019 Oct
TI  - [Correlation Analysis of Platelet Aggregation Rate Detected by Platelet Analyzer, 
      Platelet Aggregometer and Thromboelastography].
PG  - 1622-1626
LID - 10.19746/j.cnki.issn.1009-2137.2019.05.041 [doi]
AB  - OBJECTIVE: To analyze and compare the correlation of platelet aggregation rate 
      measured by platelet analyzer, platelet aggregometer and thromboelastography. 
      METHODS: The performance of platelet analyzer in platelet count and platelet 
      aggregation function was evaluated. The platelet aggregation rate of 55 patients 
      with type 2 diabetes mellitus (T2DM) before and after taking aspirin alone (32 
      cases) and clopidogrel alone (23 cases) was measured by thromboelastography, 
      platelet aggregometer and platelet analyzer respectively, and the analytical 
      results were compared. The correlation between the results measured by different 
      instruments and equipment were further analyzed and the data were included in the 
      statistical analysis. RESULTS: The precision of platelet analyzer in day and in 
      batch was 1/3 lower than the total error (7%). The contamination rate was 0.30%. 
      The slope of regression equation was 1.02 and R(2) was 0.99 in the linear range 
      of 4.15x10(9)/L to 1379.95x10(9)/L. The coincidence rate of platelet count and 
      platelet reference method was 85%, which met the requirements of industry 
      standards. The platelet aggregation rates of patients with T2DM after clopidogrel 
      or aspirin by using thromboelastography, platelet aggregometer and platelet 
      analyzer respectively was significantly lower than those whom before clopidogrel 
      administration (P<0.01). CONCLUSION: Platelet analyzer can provide reliable, 
      objective and accurate information for clinical detection of platelet count and 
      aggregation function, which is meet the requirements of industry standards, and 
      its results are similar to those of platelet aggregometer and 
      thromboelastography.
FAU - Jiang, Hui
AU  - Jiang H
AD  - Department of Blood Transfusion,The First Affiliated Hospital of Xiamen 
      University, Xiamen 361000 Fujian Province, China.
FAU - Su, Rui
AU  - Su R
AD  - Department of Hematology,The First Affiliated Hospital of Xiamen University, 
      Xiamen 361000 Fujian Province, China.
FAU - Hong, Qiang
AU  - Hong Q
AD  - Department of Blood Transfusion,The First Affiliated Hospital of Xiamen 
      University, Xiamen 361000 Fujian Province, China,E-mail: 51579866@qq.com.
LA  - chi
PT  - Journal Article
PL  - China
TA  - Zhongguo Shi Yan Xue Ye Xue Za Zhi
JT  - Zhongguo shi yan xue ye xue za zhi
JID - 101084424
RN  - 0 (Platelet Aggregation Inhibitors)
SB  - IM
MH  - *Diabetes Mellitus, Type 2
MH  - Humans
MH  - *Platelet Aggregation
MH  - Platelet Aggregation Inhibitors
MH  - Platelet Function Tests
MH  - Thrombelastography
EDAT- 2019/10/15 06:00
MHDA- 2019/11/15 06:00
CRDT- 2019/10/15 06:00
PHST- 2019/10/15 06:00 [entrez]
PHST- 2019/10/15 06:00 [pubmed]
PHST- 2019/11/15 06:00 [medline]
AID - 1009-2137(2019)05-1622-05 [pii]
AID - 10.19746/j.cnki.issn.1009-2137.2019.05.041 [doi]
PST - ppublish
SO  - Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2019 Oct;27(5):1622-1626. doi: 
      10.19746/j.cnki.issn.1009-2137.2019.05.041.