PMID- 31630372 OWN - NLM STAT- MEDLINE DCOM- 20200529 LR - 20200529 IS - 2520-8721 (Electronic) IS - 1109-3099 (Linking) VI - 18 IP - 4 DP - 2019 Dec TI - A year in type 2 diabetes mellitus: 2018 review based on the Endorama lecture. PG - 401-408 LID - 10.1007/s42000-019-00139-z [doi] AB - The aim of this article is to review and present the most important studies published in the field of type 2 diabetes mellitus (T2DM) during 2018. These studies were presented in a lecture given on this topic at the Endorama Meeting in Patras, Greece, in January 2019. In order to identify the most important and relevant articles, a search in the English language was conducted in PubMed for publications up to the end of December 2018, with special attention paid to publications in high impact factor journals. The highlights of the main Diabetes Meetings [ADA (American Diabetes Association) and EASD (European Association of Diabetes)], as well as Medscape, were also reviewed. Last but not least, press releases regarding advances in the diagnosis and treatment of T2DM were considered. We finally selected and discussed important studies concerning diagnosis, pathophysiology, and management of this very common clinical entity (19 studies). The majority of studies were clinical trials dealing with new therapeutic tools for treatment of the disease, with the greatest focus being on GLP-1RA. We also presented in brief the main points of new guidelines published for T2DM by various scientific societies (3 sets of guidelines). During 2018, not only leading diabetes associations published guidelines on the disease, but also societies belonging to other primary scientific fields. This is indicative of the awareness of physicians and scientists that T2DM constitutes today a major health problem and of the need for public health strategies for its treatment and prevention. FAU - Paschou, Stavroula A AU - Paschou SA AUID- ORCID: 0000-0002-0651-1376 AD - Division of Endocrinology and Diabetes, "Aghia Sophia" Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece. s.a.paschou@gmail.com. FAU - Alexandrides, Theodoros AU - Alexandrides T AD - Department of Endocrinology, University Hospital, Medical School, University of Patras, Rio, Patras, Greece. LA - eng PT - Journal Article PT - Review DEP - 20191019 PL - Switzerland TA - Hormones (Athens) JT - Hormones (Athens, Greece) JID - 101142469 RN - 0 (Hypoglycemic Agents) SB - IM MH - Diabetes Mellitus, Type 2/*therapy MH - Humans MH - Hypoglycemic Agents/administration & dosage/*therapeutic use OTO - NOTNLM OT - 2018 OT - DPP-4i OT - GLP-1RA OT - Guidelines OT - Insulin OT - Metformin OT - SGLT-2i OT - Type 2 diabetes mellitus EDAT- 2019/10/21 06:00 MHDA- 2020/05/30 06:00 CRDT- 2019/10/21 06:00 PHST- 2019/07/12 00:00 [received] PHST- 2019/09/22 00:00 [accepted] PHST- 2019/10/21 06:00 [pubmed] PHST- 2020/05/30 06:00 [medline] PHST- 2019/10/21 06:00 [entrez] AID - 10.1007/s42000-019-00139-z [pii] AID - 10.1007/s42000-019-00139-z [doi] PST - ppublish SO - Hormones (Athens). 2019 Dec;18(4):401-408. doi: 10.1007/s42000-019-00139-z. Epub 2019 Oct 19.