PMID- 31631237 OWN - NLM STAT- MEDLINE DCOM- 20201118 LR - 20201118 IS - 1435-702X (Electronic) IS - 0721-832X (Linking) VI - 258 IP - 1 DP - 2020 Jan TI - Comparison of anterior segment and lens biometric measurements in patients with cataract. PG - 137-146 LID - 10.1007/s00417-019-04482-0 [doi] AB - PURPOSE: This study was performed to compare anterior ocular biometric measurements of deep-range swept-source anterior segment optical coherence tomography (AS-OCT) (CASIA2) versus short-range swept-source AS-OCT (CASIA SS-1000), ultrasonography (AL-4000), and Scheimpflug camera analysis (Pentacam and EAS-1000) in patients with cataract. METHODS: One hundred eighty-five eyes of 128 participants with mild refractive error or cataract were examined. The central corneal thickness (CCT), aqueous depth (AQD), and lens thickness were obtained. The repeatability of CASIA2 measurements was assessed. RESULTS: In patients with cataract, the CCT, AQD, lens thickness, and lens anterior curvature by CASIA2 showed high intraclass correlation coefficients (ICCs) of > 0.99. Conversely, measurements of the posterior part of the lens such as lens posterior curvature showed lower ICCs. The ICCs were higher in healthy young participants than in patients with cataract. The ICCs tended to be lower in patients with mild than dense cataract. There was no statistically significant difference in the CCT and AQD between the CASIA2 and CASIA SS-1000 or in the lens thickness measurements between the CASIA2 and AL-4000 and between the CASIA2 and EAS-1000. There was a significant linear correlation in the biometric measurements between the CASIA2 and the other instruments. CONCLUSION: We evaluated the biometric measurements of the anterior eye segment by the CASIA2. The CASIA2 yielded results comparable with those of the CASIA SS-1000, ultrasonography, and Scheimpflug camera. However, mild cataract decreased the repeatability of measurements of the posterior part of the lens. FAU - Fukuda, Shinichi AU - Fukuda S AUID- ORCID: 0000-0002-4160-8229 AD - Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8575, Japan. caesar.shihtzu@gmail.com. FAU - Ueno, Yuta AU - Ueno Y AD - Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8575, Japan. FAU - Fujita, Akari AU - Fujita A AD - Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8575, Japan. FAU - Mori, Haruhiro AU - Mori H AD - Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8575, Japan. FAU - Tasaki, Kuniharu AU - Tasaki K AD - Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8575, Japan. FAU - Murakami, Tomoya AU - Murakami T AD - Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8575, Japan. FAU - Beheregaray, Simone AU - Beheregaray S AD - Department of Ophthalmology, The Queen Elizabeth Hospital, Adelaide, South Australia, Australia. FAU - Oshika, Tetsuro AU - Oshika T AD - Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8575, Japan. LA - eng PT - Journal Article DEP - 20191020 PL - Germany TA - Graefes Arch Clin Exp Ophthalmol JT - Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie JID - 8205248 SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Anterior Eye Segment/*diagnostic imaging MH - Biometry/*methods MH - Cataract/*diagnosis/physiopathology MH - Female MH - Humans MH - Lens, Crystalline/*diagnostic imaging MH - Male MH - Middle Aged MH - Tomography, Optical Coherence/*methods OTO - NOTNLM OT - Anterior segment biometry OT - CASIA2 OT - Cataract OT - Deep-range swept-source anterior segment optical coherence tomography OT - Lens biometry EDAT- 2019/10/22 06:00 MHDA- 2020/11/20 06:00 CRDT- 2019/10/22 06:00 PHST- 2019/05/31 00:00 [received] PHST- 2019/09/13 00:00 [accepted] PHST- 2019/09/02 00:00 [revised] PHST- 2019/10/22 06:00 [pubmed] PHST- 2020/11/20 06:00 [medline] PHST- 2019/10/22 06:00 [entrez] AID - 10.1007/s00417-019-04482-0 [pii] AID - 10.1007/s00417-019-04482-0 [doi] PST - ppublish SO - Graefes Arch Clin Exp Ophthalmol. 2020 Jan;258(1):137-146. doi: 10.1007/s00417-019-04482-0. Epub 2019 Oct 20.