PMID- 31638489
OWN - NLM
STAT- MEDLINE
DCOM- 20200306
LR  - 20240216
IS  - 1527-1315 (Electronic)
IS  - 0033-8419 (Print)
IS  - 0033-8419 (Linking)
VI  - 293
IP  - 3
DP  - 2019 Dec
TI  - Multicenter Safety and Practice for Off-Label Diagnostic Use of Ferumoxytol in 
      MRI.
PG  - 554-564
LID - 10.1148/radiol.2019190477 [doi]
AB  - Background Ferumoxytol is approved for use in the treatment of iron deficiency 
      anemia, but it can serve as an alternative to gadolinium-based contrast agents. 
      On the basis of postmarketing surveillance data, the Food and Drug Administration 
      issued a black box warning regarding the risks of rare but serious acute 
      hypersensitivity reactions during fast high-dose injection (510 mg iron in 17 
      seconds) for therapeutic use. Whereas single-center safety data for diagnostic 
      use have been positive, multicenter data are lacking. Purpose To report 
      multicenter safety data for off-label diagnostic ferumoxytol use. Materials and 
      Methods The multicenter ferumoxytol MRI registry was established as an open-label 
      nonrandomized surveillance databank without industry involvement. Each center 
      monitored all ferumoxytol administrations, classified adverse events (AEs) using 
      the National Cancer Institute Common Terminology Criteria for Adverse Events 
      (grade 1-5), and assessed the relationship of AEs to ferumoxytol administration. 
      AEs related to or possibly related to ferumoxytol injection were considered 
      adverse reactions. The core laboratory adjudicated the AEs and classified them 
      with the American College of Radiology (ACR) classification. Analysis of variance 
      was used to compare vital signs. Results Between January 2003 and October 2018, 
      3215 patients (median age, 58 years; range, 1 day to 96 years; 1897 male 
      patients) received 4240 ferumoxytol injections for MRI. Ferumoxytol dose ranged 
      from 1 to 11 mg per kilogram of body weight (</=510 mg iron; rate </=45 mg iron/sec). 
      There were no systematic changes in vital signs after ferumoxytol administration 
      (P > .05). No severe, life-threatening, or fatal AEs occurred. Eighty-three 
      (1.9%) of 4240 AEs were related or possibly related to ferumoxytol infusions (75 
      mild [1.8%], eight moderate [0.2%]). Thirty-one AEs were classified as 
      allergiclike reactions using ACR criteria but were consistent with minor infusion 
      reactions observed with parenteral iron. Conclusion Diagnostic ferumoxytol use 
      was well tolerated, associated with no serious adverse events, and implicated in 
      few adverse reactions. Registry results indicate a positive safety profile for 
      ferumoxytol use in MRI. (c) RSNA, 2019 Online supplemental material is available 
      for this article.
FAU - Nguyen, Kim-Lien
AU  - Nguyen KL
AUID- ORCID: 0000-0002-8854-2976
AD  - From the Diagnostic Cardiovascular Imaging Research Laboratory, Department of 
      Radiological Sciences, David Geffen School of Medicine at UCLA, 300 Medical 
      Plaza, Suite B119, Los Angeles, CA 90095 (K.L.N., T.Y., P.H., J.P.F.); Division 
      of Cardiology, David Geffen School of Medicine at UCLA and VA Greater Los Angeles 
      Healthcare System, Los Angeles, Calif (K.L.N., N.K.); Department of Radiology 
      (I.H.Z., M.R.B.), Center for Advanced Magnetic Resonance Development (I.H.Z., 
      M.R.B.), and Division of Gastroenterology, Department of Medicine (M.R.B.), Duke 
      University Medical Center, Durham, NC; Department of Diagnostic Radiology and 
      Neurology, Oregon Health Sciences University, Portland, Ore (C.G.V.); British 
      Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, 
      Edinburgh, Scotland (S.I.S., D.E.N.); Department of Imaging, Cedars-Sinai Medical 
      Center, Los Angeles, Calif (R.S.); Department of Medical Imaging, Ann & Robert H. 
      Lurie Children's Hospital of Chicago, Chicago, Ill (C.K.R., L.M.G.); Department 
      of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill 
      (C.K.R., L.M.G.); Institute of Cardiovascular and Medical Sciences, University of 
      Glasgow, Scotland (S.S., A.R.); Division of Cardiology, Department of Pediatrics 
      and Radiology, Children's Hospital of Philadelphia, Philadelphia, Pa (K.K.W., 
      M.A.F.); Department of Radiology, University of Wisconsin, Madison, Wis (L.M.G., 
      M.L.S.); Department of Radiology, University of California, San Francisco and VA 
      San Francisco Healthcare System, San Francisco, Calif (D.S., M.D.H.); Department 
      of Radiology, Weill Medical College of Cornell University, New York, NY (M.R.P.); 
      Department of Radiology, NHS Greater Glasgow and Clyde, and Institute of 
      Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, Scotland 
      (G.H.R.); and Department of Neurology and Neurosurgery, Oregon Health Sciences 
      University and VA Portland Healthcare System, Portland, Ore (E.A.N.).
FAU - Yoshida, Takegawa
AU  - Yoshida T
AD  - From the Diagnostic Cardiovascular Imaging Research Laboratory, Department of 
      Radiological Sciences, David Geffen School of Medicine at UCLA, 300 Medical 
      Plaza, Suite B119, Los Angeles, CA 90095 (K.L.N., T.Y., P.H., J.P.F.); Division 
      of Cardiology, David Geffen School of Medicine at UCLA and VA Greater Los Angeles 
      Healthcare System, Los Angeles, Calif (K.L.N., N.K.); Department of Radiology 
      (I.H.Z., M.R.B.), Center for Advanced Magnetic Resonance Development (I.H.Z., 
      M.R.B.), and Division of Gastroenterology, Department of Medicine (M.R.B.), Duke 
      University Medical Center, Durham, NC; Department of Diagnostic Radiology and 
      Neurology, Oregon Health Sciences University, Portland, Ore (C.G.V.); British 
      Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, 
      Edinburgh, Scotland (S.I.S., D.E.N.); Department of Imaging, Cedars-Sinai Medical 
      Center, Los Angeles, Calif (R.S.); Department of Medical Imaging, Ann & Robert H. 
      Lurie Children's Hospital of Chicago, Chicago, Ill (C.K.R., L.M.G.); Department 
      of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill 
      (C.K.R., L.M.G.); Institute of Cardiovascular and Medical Sciences, University of 
      Glasgow, Scotland (S.S., A.R.); Division of Cardiology, Department of Pediatrics 
      and Radiology, Children's Hospital of Philadelphia, Philadelphia, Pa (K.K.W., 
      M.A.F.); Department of Radiology, University of Wisconsin, Madison, Wis (L.M.G., 
      M.L.S.); Department of Radiology, University of California, San Francisco and VA 
      San Francisco Healthcare System, San Francisco, Calif (D.S., M.D.H.); Department 
      of Radiology, Weill Medical College of Cornell University, New York, NY (M.R.P.); 
      Department of Radiology, NHS Greater Glasgow and Clyde, and Institute of 
      Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, Scotland 
      (G.H.R.); and Department of Neurology and Neurosurgery, Oregon Health Sciences 
      University and VA Portland Healthcare System, Portland, Ore (E.A.N.).
FAU - Kathuria-Prakash, Nikhita
AU  - Kathuria-Prakash N
AD  - From the Diagnostic Cardiovascular Imaging Research Laboratory, Department of 
      Radiological Sciences, David Geffen School of Medicine at UCLA, 300 Medical 
      Plaza, Suite B119, Los Angeles, CA 90095 (K.L.N., T.Y., P.H., J.P.F.); Division 
      of Cardiology, David Geffen School of Medicine at UCLA and VA Greater Los Angeles 
      Healthcare System, Los Angeles, Calif (K.L.N., N.K.); Department of Radiology 
      (I.H.Z., M.R.B.), Center for Advanced Magnetic Resonance Development (I.H.Z., 
      M.R.B.), and Division of Gastroenterology, Department of Medicine (M.R.B.), Duke 
      University Medical Center, Durham, NC; Department of Diagnostic Radiology and 
      Neurology, Oregon Health Sciences University, Portland, Ore (C.G.V.); British 
      Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, 
      Edinburgh, Scotland (S.I.S., D.E.N.); Department of Imaging, Cedars-Sinai Medical 
      Center, Los Angeles, Calif (R.S.); Department of Medical Imaging, Ann & Robert H. 
      Lurie Children's Hospital of Chicago, Chicago, Ill (C.K.R., L.M.G.); Department 
      of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill 
      (C.K.R., L.M.G.); Institute of Cardiovascular and Medical Sciences, University of 
      Glasgow, Scotland (S.S., A.R.); Division of Cardiology, Department of Pediatrics 
      and Radiology, Children's Hospital of Philadelphia, Philadelphia, Pa (K.K.W., 
      M.A.F.); Department of Radiology, University of Wisconsin, Madison, Wis (L.M.G., 
      M.L.S.); Department of Radiology, University of California, San Francisco and VA 
      San Francisco Healthcare System, San Francisco, Calif (D.S., M.D.H.); Department 
      of Radiology, Weill Medical College of Cornell University, New York, NY (M.R.P.); 
      Department of Radiology, NHS Greater Glasgow and Clyde, and Institute of 
      Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, Scotland 
      (G.H.R.); and Department of Neurology and Neurosurgery, Oregon Health Sciences 
      University and VA Portland Healthcare System, Portland, Ore (E.A.N.).
FAU - Zaki, Islam H
AU  - Zaki IH
AUID- ORCID: 0000-0001-7026-5686
AD  - From the Diagnostic Cardiovascular Imaging Research Laboratory, Department of 
      Radiological Sciences, David Geffen School of Medicine at UCLA, 300 Medical 
      Plaza, Suite B119, Los Angeles, CA 90095 (K.L.N., T.Y., P.H., J.P.F.); Division 
      of Cardiology, David Geffen School of Medicine at UCLA and VA Greater Los Angeles 
      Healthcare System, Los Angeles, Calif (K.L.N., N.K.); Department of Radiology 
      (I.H.Z., M.R.B.), Center for Advanced Magnetic Resonance Development (I.H.Z., 
      M.R.B.), and Division of Gastroenterology, Department of Medicine (M.R.B.), Duke 
      University Medical Center, Durham, NC; Department of Diagnostic Radiology and 
      Neurology, Oregon Health Sciences University, Portland, Ore (C.G.V.); British 
      Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, 
      Edinburgh, Scotland (S.I.S., D.E.N.); Department of Imaging, Cedars-Sinai Medical 
      Center, Los Angeles, Calif (R.S.); Department of Medical Imaging, Ann & Robert H. 
      Lurie Children's Hospital of Chicago, Chicago, Ill (C.K.R., L.M.G.); Department 
      of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill 
      (C.K.R., L.M.G.); Institute of Cardiovascular and Medical Sciences, University of 
      Glasgow, Scotland (S.S., A.R.); Division of Cardiology, Department of Pediatrics 
      and Radiology, Children's Hospital of Philadelphia, Philadelphia, Pa (K.K.W., 
      M.A.F.); Department of Radiology, University of Wisconsin, Madison, Wis (L.M.G., 
      M.L.S.); Department of Radiology, University of California, San Francisco and VA 
      San Francisco Healthcare System, San Francisco, Calif (D.S., M.D.H.); Department 
      of Radiology, Weill Medical College of Cornell University, New York, NY (M.R.P.); 
      Department of Radiology, NHS Greater Glasgow and Clyde, and Institute of 
      Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, Scotland 
      (G.H.R.); and Department of Neurology and Neurosurgery, Oregon Health Sciences 
      University and VA Portland Healthcare System, Portland, Ore (E.A.N.).
FAU - Varallyay, Csanad G
AU  - Varallyay CG
AD  - From the Diagnostic Cardiovascular Imaging Research Laboratory, Department of 
      Radiological Sciences, David Geffen School of Medicine at UCLA, 300 Medical 
      Plaza, Suite B119, Los Angeles, CA 90095 (K.L.N., T.Y., P.H., J.P.F.); Division 
      of Cardiology, David Geffen School of Medicine at UCLA and VA Greater Los Angeles 
      Healthcare System, Los Angeles, Calif (K.L.N., N.K.); Department of Radiology 
      (I.H.Z., M.R.B.), Center for Advanced Magnetic Resonance Development (I.H.Z., 
      M.R.B.), and Division of Gastroenterology, Department of Medicine (M.R.B.), Duke 
      University Medical Center, Durham, NC; Department of Diagnostic Radiology and 
      Neurology, Oregon Health Sciences University, Portland, Ore (C.G.V.); British 
      Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, 
      Edinburgh, Scotland (S.I.S., D.E.N.); Department of Imaging, Cedars-Sinai Medical 
      Center, Los Angeles, Calif (R.S.); Department of Medical Imaging, Ann & Robert H. 
      Lurie Children's Hospital of Chicago, Chicago, Ill (C.K.R., L.M.G.); Department 
      of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill 
      (C.K.R., L.M.G.); Institute of Cardiovascular and Medical Sciences, University of 
      Glasgow, Scotland (S.S., A.R.); Division of Cardiology, Department of Pediatrics 
      and Radiology, Children's Hospital of Philadelphia, Philadelphia, Pa (K.K.W., 
      M.A.F.); Department of Radiology, University of Wisconsin, Madison, Wis (L.M.G., 
      M.L.S.); Department of Radiology, University of California, San Francisco and VA 
      San Francisco Healthcare System, San Francisco, Calif (D.S., M.D.H.); Department 
      of Radiology, Weill Medical College of Cornell University, New York, NY (M.R.P.); 
      Department of Radiology, NHS Greater Glasgow and Clyde, and Institute of 
      Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, Scotland 
      (G.H.R.); and Department of Neurology and Neurosurgery, Oregon Health Sciences 
      University and VA Portland Healthcare System, Portland, Ore (E.A.N.).
FAU - Semple, Scott I
AU  - Semple SI
AUID- ORCID: 0000-0002-4008-7564
AD  - From the Diagnostic Cardiovascular Imaging Research Laboratory, Department of 
      Radiological Sciences, David Geffen School of Medicine at UCLA, 300 Medical 
      Plaza, Suite B119, Los Angeles, CA 90095 (K.L.N., T.Y., P.H., J.P.F.); Division 
      of Cardiology, David Geffen School of Medicine at UCLA and VA Greater Los Angeles 
      Healthcare System, Los Angeles, Calif (K.L.N., N.K.); Department of Radiology 
      (I.H.Z., M.R.B.), Center for Advanced Magnetic Resonance Development (I.H.Z., 
      M.R.B.), and Division of Gastroenterology, Department of Medicine (M.R.B.), Duke 
      University Medical Center, Durham, NC; Department of Diagnostic Radiology and 
      Neurology, Oregon Health Sciences University, Portland, Ore (C.G.V.); British 
      Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, 
      Edinburgh, Scotland (S.I.S., D.E.N.); Department of Imaging, Cedars-Sinai Medical 
      Center, Los Angeles, Calif (R.S.); Department of Medical Imaging, Ann & Robert H. 
      Lurie Children's Hospital of Chicago, Chicago, Ill (C.K.R., L.M.G.); Department 
      of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill 
      (C.K.R., L.M.G.); Institute of Cardiovascular and Medical Sciences, University of 
      Glasgow, Scotland (S.S., A.R.); Division of Cardiology, Department of Pediatrics 
      and Radiology, Children's Hospital of Philadelphia, Philadelphia, Pa (K.K.W., 
      M.A.F.); Department of Radiology, University of Wisconsin, Madison, Wis (L.M.G., 
      M.L.S.); Department of Radiology, University of California, San Francisco and VA 
      San Francisco Healthcare System, San Francisco, Calif (D.S., M.D.H.); Department 
      of Radiology, Weill Medical College of Cornell University, New York, NY (M.R.P.); 
      Department of Radiology, NHS Greater Glasgow and Clyde, and Institute of 
      Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, Scotland 
      (G.H.R.); and Department of Neurology and Neurosurgery, Oregon Health Sciences 
      University and VA Portland Healthcare System, Portland, Ore (E.A.N.).
FAU - Saouaf, Rola
AU  - Saouaf R
AUID- ORCID: 0000-0003-0464-3786
AD  - From the Diagnostic Cardiovascular Imaging Research Laboratory, Department of 
      Radiological Sciences, David Geffen School of Medicine at UCLA, 300 Medical 
      Plaza, Suite B119, Los Angeles, CA 90095 (K.L.N., T.Y., P.H., J.P.F.); Division 
      of Cardiology, David Geffen School of Medicine at UCLA and VA Greater Los Angeles 
      Healthcare System, Los Angeles, Calif (K.L.N., N.K.); Department of Radiology 
      (I.H.Z., M.R.B.), Center for Advanced Magnetic Resonance Development (I.H.Z., 
      M.R.B.), and Division of Gastroenterology, Department of Medicine (M.R.B.), Duke 
      University Medical Center, Durham, NC; Department of Diagnostic Radiology and 
      Neurology, Oregon Health Sciences University, Portland, Ore (C.G.V.); British 
      Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, 
      Edinburgh, Scotland (S.I.S., D.E.N.); Department of Imaging, Cedars-Sinai Medical 
      Center, Los Angeles, Calif (R.S.); Department of Medical Imaging, Ann & Robert H. 
      Lurie Children's Hospital of Chicago, Chicago, Ill (C.K.R., L.M.G.); Department 
      of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill 
      (C.K.R., L.M.G.); Institute of Cardiovascular and Medical Sciences, University of 
      Glasgow, Scotland (S.S., A.R.); Division of Cardiology, Department of Pediatrics 
      and Radiology, Children's Hospital of Philadelphia, Philadelphia, Pa (K.K.W., 
      M.A.F.); Department of Radiology, University of Wisconsin, Madison, Wis (L.M.G., 
      M.L.S.); Department of Radiology, University of California, San Francisco and VA 
      San Francisco Healthcare System, San Francisco, Calif (D.S., M.D.H.); Department 
      of Radiology, Weill Medical College of Cornell University, New York, NY (M.R.P.); 
      Department of Radiology, NHS Greater Glasgow and Clyde, and Institute of 
      Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, Scotland 
      (G.H.R.); and Department of Neurology and Neurosurgery, Oregon Health Sciences 
      University and VA Portland Healthcare System, Portland, Ore (E.A.N.).
FAU - Rigsby, Cynthia K
AU  - Rigsby CK
AD  - From the Diagnostic Cardiovascular Imaging Research Laboratory, Department of 
      Radiological Sciences, David Geffen School of Medicine at UCLA, 300 Medical 
      Plaza, Suite B119, Los Angeles, CA 90095 (K.L.N., T.Y., P.H., J.P.F.); Division 
      of Cardiology, David Geffen School of Medicine at UCLA and VA Greater Los Angeles 
      Healthcare System, Los Angeles, Calif (K.L.N., N.K.); Department of Radiology 
      (I.H.Z., M.R.B.), Center for Advanced Magnetic Resonance Development (I.H.Z., 
      M.R.B.), and Division of Gastroenterology, Department of Medicine (M.R.B.), Duke 
      University Medical Center, Durham, NC; Department of Diagnostic Radiology and 
      Neurology, Oregon Health Sciences University, Portland, Ore (C.G.V.); British 
      Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, 
      Edinburgh, Scotland (S.I.S., D.E.N.); Department of Imaging, Cedars-Sinai Medical 
      Center, Los Angeles, Calif (R.S.); Department of Medical Imaging, Ann & Robert H. 
      Lurie Children's Hospital of Chicago, Chicago, Ill (C.K.R., L.M.G.); Department 
      of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill 
      (C.K.R., L.M.G.); Institute of Cardiovascular and Medical Sciences, University of 
      Glasgow, Scotland (S.S., A.R.); Division of Cardiology, Department of Pediatrics 
      and Radiology, Children's Hospital of Philadelphia, Philadelphia, Pa (K.K.W., 
      M.A.F.); Department of Radiology, University of Wisconsin, Madison, Wis (L.M.G., 
      M.L.S.); Department of Radiology, University of California, San Francisco and VA 
      San Francisco Healthcare System, San Francisco, Calif (D.S., M.D.H.); Department 
      of Radiology, Weill Medical College of Cornell University, New York, NY (M.R.P.); 
      Department of Radiology, NHS Greater Glasgow and Clyde, and Institute of 
      Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, Scotland 
      (G.H.R.); and Department of Neurology and Neurosurgery, Oregon Health Sciences 
      University and VA Portland Healthcare System, Portland, Ore (E.A.N.).
FAU - Stoumpos, Sokratis
AU  - Stoumpos S
AD  - From the Diagnostic Cardiovascular Imaging Research Laboratory, Department of 
      Radiological Sciences, David Geffen School of Medicine at UCLA, 300 Medical 
      Plaza, Suite B119, Los Angeles, CA 90095 (K.L.N., T.Y., P.H., J.P.F.); Division 
      of Cardiology, David Geffen School of Medicine at UCLA and VA Greater Los Angeles 
      Healthcare System, Los Angeles, Calif (K.L.N., N.K.); Department of Radiology 
      (I.H.Z., M.R.B.), Center for Advanced Magnetic Resonance Development (I.H.Z., 
      M.R.B.), and Division of Gastroenterology, Department of Medicine (M.R.B.), Duke 
      University Medical Center, Durham, NC; Department of Diagnostic Radiology and 
      Neurology, Oregon Health Sciences University, Portland, Ore (C.G.V.); British 
      Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, 
      Edinburgh, Scotland (S.I.S., D.E.N.); Department of Imaging, Cedars-Sinai Medical 
      Center, Los Angeles, Calif (R.S.); Department of Medical Imaging, Ann & Robert H. 
      Lurie Children's Hospital of Chicago, Chicago, Ill (C.K.R., L.M.G.); Department 
      of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill 
      (C.K.R., L.M.G.); Institute of Cardiovascular and Medical Sciences, University of 
      Glasgow, Scotland (S.S., A.R.); Division of Cardiology, Department of Pediatrics 
      and Radiology, Children's Hospital of Philadelphia, Philadelphia, Pa (K.K.W., 
      M.A.F.); Department of Radiology, University of Wisconsin, Madison, Wis (L.M.G., 
      M.L.S.); Department of Radiology, University of California, San Francisco and VA 
      San Francisco Healthcare System, San Francisco, Calif (D.S., M.D.H.); Department 
      of Radiology, Weill Medical College of Cornell University, New York, NY (M.R.P.); 
      Department of Radiology, NHS Greater Glasgow and Clyde, and Institute of 
      Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, Scotland 
      (G.H.R.); and Department of Neurology and Neurosurgery, Oregon Health Sciences 
      University and VA Portland Healthcare System, Portland, Ore (E.A.N.).
FAU - Whitehead, Kevin K
AU  - Whitehead KK
AD  - From the Diagnostic Cardiovascular Imaging Research Laboratory, Department of 
      Radiological Sciences, David Geffen School of Medicine at UCLA, 300 Medical 
      Plaza, Suite B119, Los Angeles, CA 90095 (K.L.N., T.Y., P.H., J.P.F.); Division 
      of Cardiology, David Geffen School of Medicine at UCLA and VA Greater Los Angeles 
      Healthcare System, Los Angeles, Calif (K.L.N., N.K.); Department of Radiology 
      (I.H.Z., M.R.B.), Center for Advanced Magnetic Resonance Development (I.H.Z., 
      M.R.B.), and Division of Gastroenterology, Department of Medicine (M.R.B.), Duke 
      University Medical Center, Durham, NC; Department of Diagnostic Radiology and 
      Neurology, Oregon Health Sciences University, Portland, Ore (C.G.V.); British 
      Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, 
      Edinburgh, Scotland (S.I.S., D.E.N.); Department of Imaging, Cedars-Sinai Medical 
      Center, Los Angeles, Calif (R.S.); Department of Medical Imaging, Ann & Robert H. 
      Lurie Children's Hospital of Chicago, Chicago, Ill (C.K.R., L.M.G.); Department 
      of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill 
      (C.K.R., L.M.G.); Institute of Cardiovascular and Medical Sciences, University of 
      Glasgow, Scotland (S.S., A.R.); Division of Cardiology, Department of Pediatrics 
      and Radiology, Children's Hospital of Philadelphia, Philadelphia, Pa (K.K.W., 
      M.A.F.); Department of Radiology, University of Wisconsin, Madison, Wis (L.M.G., 
      M.L.S.); Department of Radiology, University of California, San Francisco and VA 
      San Francisco Healthcare System, San Francisco, Calif (D.S., M.D.H.); Department 
      of Radiology, Weill Medical College of Cornell University, New York, NY (M.R.P.); 
      Department of Radiology, NHS Greater Glasgow and Clyde, and Institute of 
      Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, Scotland 
      (G.H.R.); and Department of Neurology and Neurosurgery, Oregon Health Sciences 
      University and VA Portland Healthcare System, Portland, Ore (E.A.N.).
FAU - Griffin, Lindsay M
AU  - Griffin LM
AD  - From the Diagnostic Cardiovascular Imaging Research Laboratory, Department of 
      Radiological Sciences, David Geffen School of Medicine at UCLA, 300 Medical 
      Plaza, Suite B119, Los Angeles, CA 90095 (K.L.N., T.Y., P.H., J.P.F.); Division 
      of Cardiology, David Geffen School of Medicine at UCLA and VA Greater Los Angeles 
      Healthcare System, Los Angeles, Calif (K.L.N., N.K.); Department of Radiology 
      (I.H.Z., M.R.B.), Center for Advanced Magnetic Resonance Development (I.H.Z., 
      M.R.B.), and Division of Gastroenterology, Department of Medicine (M.R.B.), Duke 
      University Medical Center, Durham, NC; Department of Diagnostic Radiology and 
      Neurology, Oregon Health Sciences University, Portland, Ore (C.G.V.); British 
      Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, 
      Edinburgh, Scotland (S.I.S., D.E.N.); Department of Imaging, Cedars-Sinai Medical 
      Center, Los Angeles, Calif (R.S.); Department of Medical Imaging, Ann & Robert H. 
      Lurie Children's Hospital of Chicago, Chicago, Ill (C.K.R., L.M.G.); Department 
      of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill 
      (C.K.R., L.M.G.); Institute of Cardiovascular and Medical Sciences, University of 
      Glasgow, Scotland (S.S., A.R.); Division of Cardiology, Department of Pediatrics 
      and Radiology, Children's Hospital of Philadelphia, Philadelphia, Pa (K.K.W., 
      M.A.F.); Department of Radiology, University of Wisconsin, Madison, Wis (L.M.G., 
      M.L.S.); Department of Radiology, University of California, San Francisco and VA 
      San Francisco Healthcare System, San Francisco, Calif (D.S., M.D.H.); Department 
      of Radiology, Weill Medical College of Cornell University, New York, NY (M.R.P.); 
      Department of Radiology, NHS Greater Glasgow and Clyde, and Institute of 
      Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, Scotland 
      (G.H.R.); and Department of Neurology and Neurosurgery, Oregon Health Sciences 
      University and VA Portland Healthcare System, Portland, Ore (E.A.N.).
FAU - Saloner, David
AU  - Saloner D
AUID- ORCID: 0000-0002-6989-8547
AD  - From the Diagnostic Cardiovascular Imaging Research Laboratory, Department of 
      Radiological Sciences, David Geffen School of Medicine at UCLA, 300 Medical 
      Plaza, Suite B119, Los Angeles, CA 90095 (K.L.N., T.Y., P.H., J.P.F.); Division 
      of Cardiology, David Geffen School of Medicine at UCLA and VA Greater Los Angeles 
      Healthcare System, Los Angeles, Calif (K.L.N., N.K.); Department of Radiology 
      (I.H.Z., M.R.B.), Center for Advanced Magnetic Resonance Development (I.H.Z., 
      M.R.B.), and Division of Gastroenterology, Department of Medicine (M.R.B.), Duke 
      University Medical Center, Durham, NC; Department of Diagnostic Radiology and 
      Neurology, Oregon Health Sciences University, Portland, Ore (C.G.V.); British 
      Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, 
      Edinburgh, Scotland (S.I.S., D.E.N.); Department of Imaging, Cedars-Sinai Medical 
      Center, Los Angeles, Calif (R.S.); Department of Medical Imaging, Ann & Robert H. 
      Lurie Children's Hospital of Chicago, Chicago, Ill (C.K.R., L.M.G.); Department 
      of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill 
      (C.K.R., L.M.G.); Institute of Cardiovascular and Medical Sciences, University of 
      Glasgow, Scotland (S.S., A.R.); Division of Cardiology, Department of Pediatrics 
      and Radiology, Children's Hospital of Philadelphia, Philadelphia, Pa (K.K.W., 
      M.A.F.); Department of Radiology, University of Wisconsin, Madison, Wis (L.M.G., 
      M.L.S.); Department of Radiology, University of California, San Francisco and VA 
      San Francisco Healthcare System, San Francisco, Calif (D.S., M.D.H.); Department 
      of Radiology, Weill Medical College of Cornell University, New York, NY (M.R.P.); 
      Department of Radiology, NHS Greater Glasgow and Clyde, and Institute of 
      Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, Scotland 
      (G.H.R.); and Department of Neurology and Neurosurgery, Oregon Health Sciences 
      University and VA Portland Healthcare System, Portland, Ore (E.A.N.).
FAU - Hope, Michael D
AU  - Hope MD
AD  - From the Diagnostic Cardiovascular Imaging Research Laboratory, Department of 
      Radiological Sciences, David Geffen School of Medicine at UCLA, 300 Medical 
      Plaza, Suite B119, Los Angeles, CA 90095 (K.L.N., T.Y., P.H., J.P.F.); Division 
      of Cardiology, David Geffen School of Medicine at UCLA and VA Greater Los Angeles 
      Healthcare System, Los Angeles, Calif (K.L.N., N.K.); Department of Radiology 
      (I.H.Z., M.R.B.), Center for Advanced Magnetic Resonance Development (I.H.Z., 
      M.R.B.), and Division of Gastroenterology, Department of Medicine (M.R.B.), Duke 
      University Medical Center, Durham, NC; Department of Diagnostic Radiology and 
      Neurology, Oregon Health Sciences University, Portland, Ore (C.G.V.); British 
      Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, 
      Edinburgh, Scotland (S.I.S., D.E.N.); Department of Imaging, Cedars-Sinai Medical 
      Center, Los Angeles, Calif (R.S.); Department of Medical Imaging, Ann & Robert H. 
      Lurie Children's Hospital of Chicago, Chicago, Ill (C.K.R., L.M.G.); Department 
      of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill 
      (C.K.R., L.M.G.); Institute of Cardiovascular and Medical Sciences, University of 
      Glasgow, Scotland (S.S., A.R.); Division of Cardiology, Department of Pediatrics 
      and Radiology, Children's Hospital of Philadelphia, Philadelphia, Pa (K.K.W., 
      M.A.F.); Department of Radiology, University of Wisconsin, Madison, Wis (L.M.G., 
      M.L.S.); Department of Radiology, University of California, San Francisco and VA 
      San Francisco Healthcare System, San Francisco, Calif (D.S., M.D.H.); Department 
      of Radiology, Weill Medical College of Cornell University, New York, NY (M.R.P.); 
      Department of Radiology, NHS Greater Glasgow and Clyde, and Institute of 
      Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, Scotland 
      (G.H.R.); and Department of Neurology and Neurosurgery, Oregon Health Sciences 
      University and VA Portland Healthcare System, Portland, Ore (E.A.N.).
FAU - Prince, Martin R
AU  - Prince MR
AUID- ORCID: 0000-0002-9883-0584
AD  - From the Diagnostic Cardiovascular Imaging Research Laboratory, Department of 
      Radiological Sciences, David Geffen School of Medicine at UCLA, 300 Medical 
      Plaza, Suite B119, Los Angeles, CA 90095 (K.L.N., T.Y., P.H., J.P.F.); Division 
      of Cardiology, David Geffen School of Medicine at UCLA and VA Greater Los Angeles 
      Healthcare System, Los Angeles, Calif (K.L.N., N.K.); Department of Radiology 
      (I.H.Z., M.R.B.), Center for Advanced Magnetic Resonance Development (I.H.Z., 
      M.R.B.), and Division of Gastroenterology, Department of Medicine (M.R.B.), Duke 
      University Medical Center, Durham, NC; Department of Diagnostic Radiology and 
      Neurology, Oregon Health Sciences University, Portland, Ore (C.G.V.); British 
      Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, 
      Edinburgh, Scotland (S.I.S., D.E.N.); Department of Imaging, Cedars-Sinai Medical 
      Center, Los Angeles, Calif (R.S.); Department of Medical Imaging, Ann & Robert H. 
      Lurie Children's Hospital of Chicago, Chicago, Ill (C.K.R., L.M.G.); Department 
      of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill 
      (C.K.R., L.M.G.); Institute of Cardiovascular and Medical Sciences, University of 
      Glasgow, Scotland (S.S., A.R.); Division of Cardiology, Department of Pediatrics 
      and Radiology, Children's Hospital of Philadelphia, Philadelphia, Pa (K.K.W., 
      M.A.F.); Department of Radiology, University of Wisconsin, Madison, Wis (L.M.G., 
      M.L.S.); Department of Radiology, University of California, San Francisco and VA 
      San Francisco Healthcare System, San Francisco, Calif (D.S., M.D.H.); Department 
      of Radiology, Weill Medical College of Cornell University, New York, NY (M.R.P.); 
      Department of Radiology, NHS Greater Glasgow and Clyde, and Institute of 
      Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, Scotland 
      (G.H.R.); and Department of Neurology and Neurosurgery, Oregon Health Sciences 
      University and VA Portland Healthcare System, Portland, Ore (E.A.N.).
FAU - Fogel, Mark A
AU  - Fogel MA
AD  - From the Diagnostic Cardiovascular Imaging Research Laboratory, Department of 
      Radiological Sciences, David Geffen School of Medicine at UCLA, 300 Medical 
      Plaza, Suite B119, Los Angeles, CA 90095 (K.L.N., T.Y., P.H., J.P.F.); Division 
      of Cardiology, David Geffen School of Medicine at UCLA and VA Greater Los Angeles 
      Healthcare System, Los Angeles, Calif (K.L.N., N.K.); Department of Radiology 
      (I.H.Z., M.R.B.), Center for Advanced Magnetic Resonance Development (I.H.Z., 
      M.R.B.), and Division of Gastroenterology, Department of Medicine (M.R.B.), Duke 
      University Medical Center, Durham, NC; Department of Diagnostic Radiology and 
      Neurology, Oregon Health Sciences University, Portland, Ore (C.G.V.); British 
      Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, 
      Edinburgh, Scotland (S.I.S., D.E.N.); Department of Imaging, Cedars-Sinai Medical 
      Center, Los Angeles, Calif (R.S.); Department of Medical Imaging, Ann & Robert H. 
      Lurie Children's Hospital of Chicago, Chicago, Ill (C.K.R., L.M.G.); Department 
      of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill 
      (C.K.R., L.M.G.); Institute of Cardiovascular and Medical Sciences, University of 
      Glasgow, Scotland (S.S., A.R.); Division of Cardiology, Department of Pediatrics 
      and Radiology, Children's Hospital of Philadelphia, Philadelphia, Pa (K.K.W., 
      M.A.F.); Department of Radiology, University of Wisconsin, Madison, Wis (L.M.G., 
      M.L.S.); Department of Radiology, University of California, San Francisco and VA 
      San Francisco Healthcare System, San Francisco, Calif (D.S., M.D.H.); Department 
      of Radiology, Weill Medical College of Cornell University, New York, NY (M.R.P.); 
      Department of Radiology, NHS Greater Glasgow and Clyde, and Institute of 
      Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, Scotland 
      (G.H.R.); and Department of Neurology and Neurosurgery, Oregon Health Sciences 
      University and VA Portland Healthcare System, Portland, Ore (E.A.N.).
FAU - Schiebler, Mark L
AU  - Schiebler ML
AUID- ORCID: 0000-0002-9120-5428
AD  - From the Diagnostic Cardiovascular Imaging Research Laboratory, Department of 
      Radiological Sciences, David Geffen School of Medicine at UCLA, 300 Medical 
      Plaza, Suite B119, Los Angeles, CA 90095 (K.L.N., T.Y., P.H., J.P.F.); Division 
      of Cardiology, David Geffen School of Medicine at UCLA and VA Greater Los Angeles 
      Healthcare System, Los Angeles, Calif (K.L.N., N.K.); Department of Radiology 
      (I.H.Z., M.R.B.), Center for Advanced Magnetic Resonance Development (I.H.Z., 
      M.R.B.), and Division of Gastroenterology, Department of Medicine (M.R.B.), Duke 
      University Medical Center, Durham, NC; Department of Diagnostic Radiology and 
      Neurology, Oregon Health Sciences University, Portland, Ore (C.G.V.); British 
      Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, 
      Edinburgh, Scotland (S.I.S., D.E.N.); Department of Imaging, Cedars-Sinai Medical 
      Center, Los Angeles, Calif (R.S.); Department of Medical Imaging, Ann & Robert H. 
      Lurie Children's Hospital of Chicago, Chicago, Ill (C.K.R., L.M.G.); Department 
      of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill 
      (C.K.R., L.M.G.); Institute of Cardiovascular and Medical Sciences, University of 
      Glasgow, Scotland (S.S., A.R.); Division of Cardiology, Department of Pediatrics 
      and Radiology, Children's Hospital of Philadelphia, Philadelphia, Pa (K.K.W., 
      M.A.F.); Department of Radiology, University of Wisconsin, Madison, Wis (L.M.G., 
      M.L.S.); Department of Radiology, University of California, San Francisco and VA 
      San Francisco Healthcare System, San Francisco, Calif (D.S., M.D.H.); Department 
      of Radiology, Weill Medical College of Cornell University, New York, NY (M.R.P.); 
      Department of Radiology, NHS Greater Glasgow and Clyde, and Institute of 
      Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, Scotland 
      (G.H.R.); and Department of Neurology and Neurosurgery, Oregon Health Sciences 
      University and VA Portland Healthcare System, Portland, Ore (E.A.N.).
FAU - Roditi, Giles H
AU  - Roditi GH
AD  - From the Diagnostic Cardiovascular Imaging Research Laboratory, Department of 
      Radiological Sciences, David Geffen School of Medicine at UCLA, 300 Medical 
      Plaza, Suite B119, Los Angeles, CA 90095 (K.L.N., T.Y., P.H., J.P.F.); Division 
      of Cardiology, David Geffen School of Medicine at UCLA and VA Greater Los Angeles 
      Healthcare System, Los Angeles, Calif (K.L.N., N.K.); Department of Radiology 
      (I.H.Z., M.R.B.), Center for Advanced Magnetic Resonance Development (I.H.Z., 
      M.R.B.), and Division of Gastroenterology, Department of Medicine (M.R.B.), Duke 
      University Medical Center, Durham, NC; Department of Diagnostic Radiology and 
      Neurology, Oregon Health Sciences University, Portland, Ore (C.G.V.); British 
      Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, 
      Edinburgh, Scotland (S.I.S., D.E.N.); Department of Imaging, Cedars-Sinai Medical 
      Center, Los Angeles, Calif (R.S.); Department of Medical Imaging, Ann & Robert H. 
      Lurie Children's Hospital of Chicago, Chicago, Ill (C.K.R., L.M.G.); Department 
      of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill 
      (C.K.R., L.M.G.); Institute of Cardiovascular and Medical Sciences, University of 
      Glasgow, Scotland (S.S., A.R.); Division of Cardiology, Department of Pediatrics 
      and Radiology, Children's Hospital of Philadelphia, Philadelphia, Pa (K.K.W., 
      M.A.F.); Department of Radiology, University of Wisconsin, Madison, Wis (L.M.G., 
      M.L.S.); Department of Radiology, University of California, San Francisco and VA 
      San Francisco Healthcare System, San Francisco, Calif (D.S., M.D.H.); Department 
      of Radiology, Weill Medical College of Cornell University, New York, NY (M.R.P.); 
      Department of Radiology, NHS Greater Glasgow and Clyde, and Institute of 
      Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, Scotland 
      (G.H.R.); and Department of Neurology and Neurosurgery, Oregon Health Sciences 
      University and VA Portland Healthcare System, Portland, Ore (E.A.N.).
FAU - Radjenovic, Aleksandra
AU  - Radjenovic A
AUID- ORCID: 0000-0002-1742-6863
AD  - From the Diagnostic Cardiovascular Imaging Research Laboratory, Department of 
      Radiological Sciences, David Geffen School of Medicine at UCLA, 300 Medical 
      Plaza, Suite B119, Los Angeles, CA 90095 (K.L.N., T.Y., P.H., J.P.F.); Division 
      of Cardiology, David Geffen School of Medicine at UCLA and VA Greater Los Angeles 
      Healthcare System, Los Angeles, Calif (K.L.N., N.K.); Department of Radiology 
      (I.H.Z., M.R.B.), Center for Advanced Magnetic Resonance Development (I.H.Z., 
      M.R.B.), and Division of Gastroenterology, Department of Medicine (M.R.B.), Duke 
      University Medical Center, Durham, NC; Department of Diagnostic Radiology and 
      Neurology, Oregon Health Sciences University, Portland, Ore (C.G.V.); British 
      Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, 
      Edinburgh, Scotland (S.I.S., D.E.N.); Department of Imaging, Cedars-Sinai Medical 
      Center, Los Angeles, Calif (R.S.); Department of Medical Imaging, Ann & Robert H. 
      Lurie Children's Hospital of Chicago, Chicago, Ill (C.K.R., L.M.G.); Department 
      of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill 
      (C.K.R., L.M.G.); Institute of Cardiovascular and Medical Sciences, University of 
      Glasgow, Scotland (S.S., A.R.); Division of Cardiology, Department of Pediatrics 
      and Radiology, Children's Hospital of Philadelphia, Philadelphia, Pa (K.K.W., 
      M.A.F.); Department of Radiology, University of Wisconsin, Madison, Wis (L.M.G., 
      M.L.S.); Department of Radiology, University of California, San Francisco and VA 
      San Francisco Healthcare System, San Francisco, Calif (D.S., M.D.H.); Department 
      of Radiology, Weill Medical College of Cornell University, New York, NY (M.R.P.); 
      Department of Radiology, NHS Greater Glasgow and Clyde, and Institute of 
      Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, Scotland 
      (G.H.R.); and Department of Neurology and Neurosurgery, Oregon Health Sciences 
      University and VA Portland Healthcare System, Portland, Ore (E.A.N.).
FAU - Newby, David E
AU  - Newby DE
AD  - From the Diagnostic Cardiovascular Imaging Research Laboratory, Department of 
      Radiological Sciences, David Geffen School of Medicine at UCLA, 300 Medical 
      Plaza, Suite B119, Los Angeles, CA 90095 (K.L.N., T.Y., P.H., J.P.F.); Division 
      of Cardiology, David Geffen School of Medicine at UCLA and VA Greater Los Angeles 
      Healthcare System, Los Angeles, Calif (K.L.N., N.K.); Department of Radiology 
      (I.H.Z., M.R.B.), Center for Advanced Magnetic Resonance Development (I.H.Z., 
      M.R.B.), and Division of Gastroenterology, Department of Medicine (M.R.B.), Duke 
      University Medical Center, Durham, NC; Department of Diagnostic Radiology and 
      Neurology, Oregon Health Sciences University, Portland, Ore (C.G.V.); British 
      Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, 
      Edinburgh, Scotland (S.I.S., D.E.N.); Department of Imaging, Cedars-Sinai Medical 
      Center, Los Angeles, Calif (R.S.); Department of Medical Imaging, Ann & Robert H. 
      Lurie Children's Hospital of Chicago, Chicago, Ill (C.K.R., L.M.G.); Department 
      of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill 
      (C.K.R., L.M.G.); Institute of Cardiovascular and Medical Sciences, University of 
      Glasgow, Scotland (S.S., A.R.); Division of Cardiology, Department of Pediatrics 
      and Radiology, Children's Hospital of Philadelphia, Philadelphia, Pa (K.K.W., 
      M.A.F.); Department of Radiology, University of Wisconsin, Madison, Wis (L.M.G., 
      M.L.S.); Department of Radiology, University of California, San Francisco and VA 
      San Francisco Healthcare System, San Francisco, Calif (D.S., M.D.H.); Department 
      of Radiology, Weill Medical College of Cornell University, New York, NY (M.R.P.); 
      Department of Radiology, NHS Greater Glasgow and Clyde, and Institute of 
      Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, Scotland 
      (G.H.R.); and Department of Neurology and Neurosurgery, Oregon Health Sciences 
      University and VA Portland Healthcare System, Portland, Ore (E.A.N.).
FAU - Neuwelt, Edward A
AU  - Neuwelt EA
AD  - From the Diagnostic Cardiovascular Imaging Research Laboratory, Department of 
      Radiological Sciences, David Geffen School of Medicine at UCLA, 300 Medical 
      Plaza, Suite B119, Los Angeles, CA 90095 (K.L.N., T.Y., P.H., J.P.F.); Division 
      of Cardiology, David Geffen School of Medicine at UCLA and VA Greater Los Angeles 
      Healthcare System, Los Angeles, Calif (K.L.N., N.K.); Department of Radiology 
      (I.H.Z., M.R.B.), Center for Advanced Magnetic Resonance Development (I.H.Z., 
      M.R.B.), and Division of Gastroenterology, Department of Medicine (M.R.B.), Duke 
      University Medical Center, Durham, NC; Department of Diagnostic Radiology and 
      Neurology, Oregon Health Sciences University, Portland, Ore (C.G.V.); British 
      Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, 
      Edinburgh, Scotland (S.I.S., D.E.N.); Department of Imaging, Cedars-Sinai Medical 
      Center, Los Angeles, Calif (R.S.); Department of Medical Imaging, Ann & Robert H. 
      Lurie Children's Hospital of Chicago, Chicago, Ill (C.K.R., L.M.G.); Department 
      of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill 
      (C.K.R., L.M.G.); Institute of Cardiovascular and Medical Sciences, University of 
      Glasgow, Scotland (S.S., A.R.); Division of Cardiology, Department of Pediatrics 
      and Radiology, Children's Hospital of Philadelphia, Philadelphia, Pa (K.K.W., 
      M.A.F.); Department of Radiology, University of Wisconsin, Madison, Wis (L.M.G., 
      M.L.S.); Department of Radiology, University of California, San Francisco and VA 
      San Francisco Healthcare System, San Francisco, Calif (D.S., M.D.H.); Department 
      of Radiology, Weill Medical College of Cornell University, New York, NY (M.R.P.); 
      Department of Radiology, NHS Greater Glasgow and Clyde, and Institute of 
      Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, Scotland 
      (G.H.R.); and Department of Neurology and Neurosurgery, Oregon Health Sciences 
      University and VA Portland Healthcare System, Portland, Ore (E.A.N.).
FAU - Bashir, Mustafa R
AU  - Bashir MR
AUID- ORCID: 0000-0001-8800-5057
AD  - From the Diagnostic Cardiovascular Imaging Research Laboratory, Department of 
      Radiological Sciences, David Geffen School of Medicine at UCLA, 300 Medical 
      Plaza, Suite B119, Los Angeles, CA 90095 (K.L.N., T.Y., P.H., J.P.F.); Division 
      of Cardiology, David Geffen School of Medicine at UCLA and VA Greater Los Angeles 
      Healthcare System, Los Angeles, Calif (K.L.N., N.K.); Department of Radiology 
      (I.H.Z., M.R.B.), Center for Advanced Magnetic Resonance Development (I.H.Z., 
      M.R.B.), and Division of Gastroenterology, Department of Medicine (M.R.B.), Duke 
      University Medical Center, Durham, NC; Department of Diagnostic Radiology and 
      Neurology, Oregon Health Sciences University, Portland, Ore (C.G.V.); British 
      Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, 
      Edinburgh, Scotland (S.I.S., D.E.N.); Department of Imaging, Cedars-Sinai Medical 
      Center, Los Angeles, Calif (R.S.); Department of Medical Imaging, Ann & Robert H. 
      Lurie Children's Hospital of Chicago, Chicago, Ill (C.K.R., L.M.G.); Department 
      of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill 
      (C.K.R., L.M.G.); Institute of Cardiovascular and Medical Sciences, University of 
      Glasgow, Scotland (S.S., A.R.); Division of Cardiology, Department of Pediatrics 
      and Radiology, Children's Hospital of Philadelphia, Philadelphia, Pa (K.K.W., 
      M.A.F.); Department of Radiology, University of Wisconsin, Madison, Wis (L.M.G., 
      M.L.S.); Department of Radiology, University of California, San Francisco and VA 
      San Francisco Healthcare System, San Francisco, Calif (D.S., M.D.H.); Department 
      of Radiology, Weill Medical College of Cornell University, New York, NY (M.R.P.); 
      Department of Radiology, NHS Greater Glasgow and Clyde, and Institute of 
      Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, Scotland 
      (G.H.R.); and Department of Neurology and Neurosurgery, Oregon Health Sciences 
      University and VA Portland Healthcare System, Portland, Ore (E.A.N.).
FAU - Hu, Peng
AU  - Hu P
AD  - From the Diagnostic Cardiovascular Imaging Research Laboratory, Department of 
      Radiological Sciences, David Geffen School of Medicine at UCLA, 300 Medical 
      Plaza, Suite B119, Los Angeles, CA 90095 (K.L.N., T.Y., P.H., J.P.F.); Division 
      of Cardiology, David Geffen School of Medicine at UCLA and VA Greater Los Angeles 
      Healthcare System, Los Angeles, Calif (K.L.N., N.K.); Department of Radiology 
      (I.H.Z., M.R.B.), Center for Advanced Magnetic Resonance Development (I.H.Z., 
      M.R.B.), and Division of Gastroenterology, Department of Medicine (M.R.B.), Duke 
      University Medical Center, Durham, NC; Department of Diagnostic Radiology and 
      Neurology, Oregon Health Sciences University, Portland, Ore (C.G.V.); British 
      Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, 
      Edinburgh, Scotland (S.I.S., D.E.N.); Department of Imaging, Cedars-Sinai Medical 
      Center, Los Angeles, Calif (R.S.); Department of Medical Imaging, Ann & Robert H. 
      Lurie Children's Hospital of Chicago, Chicago, Ill (C.K.R., L.M.G.); Department 
      of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill 
      (C.K.R., L.M.G.); Institute of Cardiovascular and Medical Sciences, University of 
      Glasgow, Scotland (S.S., A.R.); Division of Cardiology, Department of Pediatrics 
      and Radiology, Children's Hospital of Philadelphia, Philadelphia, Pa (K.K.W., 
      M.A.F.); Department of Radiology, University of Wisconsin, Madison, Wis (L.M.G., 
      M.L.S.); Department of Radiology, University of California, San Francisco and VA 
      San Francisco Healthcare System, San Francisco, Calif (D.S., M.D.H.); Department 
      of Radiology, Weill Medical College of Cornell University, New York, NY (M.R.P.); 
      Department of Radiology, NHS Greater Glasgow and Clyde, and Institute of 
      Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, Scotland 
      (G.H.R.); and Department of Neurology and Neurosurgery, Oregon Health Sciences 
      University and VA Portland Healthcare System, Portland, Ore (E.A.N.).
FAU - Finn, J Paul
AU  - Finn JP
AD  - From the Diagnostic Cardiovascular Imaging Research Laboratory, Department of 
      Radiological Sciences, David Geffen School of Medicine at UCLA, 300 Medical 
      Plaza, Suite B119, Los Angeles, CA 90095 (K.L.N., T.Y., P.H., J.P.F.); Division 
      of Cardiology, David Geffen School of Medicine at UCLA and VA Greater Los Angeles 
      Healthcare System, Los Angeles, Calif (K.L.N., N.K.); Department of Radiology 
      (I.H.Z., M.R.B.), Center for Advanced Magnetic Resonance Development (I.H.Z., 
      M.R.B.), and Division of Gastroenterology, Department of Medicine (M.R.B.), Duke 
      University Medical Center, Durham, NC; Department of Diagnostic Radiology and 
      Neurology, Oregon Health Sciences University, Portland, Ore (C.G.V.); British 
      Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, 
      Edinburgh, Scotland (S.I.S., D.E.N.); Department of Imaging, Cedars-Sinai Medical 
      Center, Los Angeles, Calif (R.S.); Department of Medical Imaging, Ann & Robert H. 
      Lurie Children's Hospital of Chicago, Chicago, Ill (C.K.R., L.M.G.); Department 
      of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill 
      (C.K.R., L.M.G.); Institute of Cardiovascular and Medical Sciences, University of 
      Glasgow, Scotland (S.S., A.R.); Division of Cardiology, Department of Pediatrics 
      and Radiology, Children's Hospital of Philadelphia, Philadelphia, Pa (K.K.W., 
      M.A.F.); Department of Radiology, University of Wisconsin, Madison, Wis (L.M.G., 
      M.L.S.); Department of Radiology, University of California, San Francisco and VA 
      San Francisco Healthcare System, San Francisco, Calif (D.S., M.D.H.); Department 
      of Radiology, Weill Medical College of Cornell University, New York, NY (M.R.P.); 
      Department of Radiology, NHS Greater Glasgow and Clyde, and Institute of 
      Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, Scotland 
      (G.H.R.); and Department of Neurology and Neurosurgery, Oregon Health Sciences 
      University and VA Portland Healthcare System, Portland, Ore (E.A.N.).
LA  - eng
GR  - R01 CA199111/CA/NCI NIH HHS/United States
GR  - MC_PC_12040/MRC_/Medical Research Council/United Kingdom
GR  - ETM/266/CSO_/Chief Scientist Office/United Kingdom
GR  - WT103782AIA/WT_/Wellcome Trust/United Kingdom
GR  - I01 CX001901/CX/CSRD VA/United States
GR  - G0701127/MRC_/Medical Research Council/United Kingdom
GR  - UL1 TR001881/TR/NCATS NIH HHS/United States
GR  - R01 HL127153/HL/NHLBI NIH HHS/United States
GR  - RE/13/5/30177/BHF_/British Heart Foundation/United Kingdom
GR  - I01 BX003897/BX/BLRD VA/United States
GR  - R25 EB016671/EB/NIBIB NIH HHS/United States
GR  - RE/13/3/30183/BHF_/British Heart Foundation/United Kingdom
GR  - CH/09/002/26360/BHF_/British Heart Foundation/United Kingdom
GR  - WT_/Wellcome Trust/United Kingdom
GR  - R01 HL114118/HL/NHLBI NIH HHS/United States
GR  - HHSN261200800001C/RC/CCR NIH HHS/United States
GR  - R01 CA137488/CA/NCI NIH HHS/United States
GR  - CH/09/002/BHF_/British Heart Foundation/United Kingdom
GR  - HHSN261200800001E/CA/NCI NIH HHS/United States
PT  - Journal Article
PT  - Multicenter Study
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20191022
PL  - United States
TA  - Radiology
JT  - Radiology
JID - 0401260
RN  - 0 (Contrast Media)
RN  - XM0M87F357 (Ferrosoferric Oxide)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Child
MH  - Child, Preschool
MH  - Contrast Media/*adverse effects
MH  - Drug-Related Side Effects and Adverse Reactions
MH  - Female
MH  - Ferrosoferric Oxide/*adverse effects
MH  - Humans
MH  - Infant
MH  - Infant, Newborn
MH  - *Magnetic Resonance Imaging
MH  - Male
MH  - Middle Aged
MH  - *Off-Label Use
MH  - Registries
PMC - PMC6884068
EDAT- 2019/10/23 06:00
MHDA- 2020/03/07 06:00
PMCR- 2020/12/01
CRDT- 2019/10/23 06:00
PHST- 2019/10/23 06:00 [pubmed]
PHST- 2020/03/07 06:00 [medline]
PHST- 2019/10/23 06:00 [entrez]
PHST- 2020/12/01 00:00 [pmc-release]
AID - 10.1148/radiol.2019190477 [doi]
PST - ppublish
SO  - Radiology. 2019 Dec;293(3):554-564. doi: 10.1148/radiol.2019190477. Epub 2019 Oct 
      22.