PMID- 31638908
OWN - NLM
STAT- MEDLINE
DCOM- 20200615
LR  - 20200615
IS  - 1471-2261 (Electronic)
IS  - 1471-2261 (Linking)
VI  - 19
IP  - 1
DP  - 2019 Oct 21
TI  - Epidemiology and risk factors of patients with types of acute coronary syndrome 
      presenting to a tertiary care hospital in Sri Lanka.
PG  - 229
LID - 10.1186/s12872-019-1217-x [doi]
LID - 229
AB  - BACKGROUND: Acute Coronary Syndrome (ACS) is one of the leading causes of death 
      worldwide and studies have shown higher mortality rates and premature death in 
      South Asian countries. The occurrence and effect of risk factors differ by type 
      ofACS.Epidemiological studies in the Sri Lankan population are limited. METHODS: 
      This is a cross sectional descriptive study conducted at the Teaching Hospital 
      Peradeniya, Sri Lanka among patients presenting with ACS. Data was collected by 
      an interviewer administered structured questionnaire and epidemiological patterns 
      and risk factors were analyzed. RESULTS: The sample of 300 patients had a mean 
      age of 61.3+/- 12.6 and male sex showed higher association with all three type of 
      ACS compared to female with a P value of 0.001. This study showed higher mean age 
      of 62.2 +/- 11.4 years amongst unstable angina (UA) patients and 61.9 +/- 14.5 years 
      amongst non ST elevation myocardial infarction (NSTEMI) patients compared to 
      59.2 +/- 11.2 years for ST elevation myocardial infarction (STEMI) patients with no 
      significant statistical difference (P = 0.246). Approximately 55.8% STEMI 
      patients, 39.8% UA and 35.5% NSTEMI patients were smokers indicating a 
      significant association between smoking and STEMI (P = 0.017). Nearly 54.5% 
      STEMI, 35.4% UA and 32.7% NSTEMI patients consumed alcohol and there was a very 
      strong association between alcohol consumption and STEMI (P = 0.006). Almost 
      51.8% NSTEMI patients, 47.8% UA patients and 29.9% STEMI patients had 
      hypertension(HT) (P = 0.008) indicating significant association of HT with UA and 
      NSTEMI. About 33.6% UA patients and 30.0% NSTEMI patients had DM whilst only 
      22.1% of STEMI patients had DM of no significance (p = 0.225). Around 15.0% 
      patients with UA, 25.5% with NSTEMI and 11.7% with STEMI had dyslipidemia 
      (P = 0.032). There was a very strong association between a past history of ACS or 
      stable angina with NSTEMI and UA (P = 0.001). CONCLUSION: Smoking and alcohol 
      abuse are significantly associated with STEMI.Patients with NSTEMI or Unstable 
      Angina had higher rates of hypertension and were more likely to have a history of 
      ACS or stable angina than STEMI patients. Patients with NSTEMI were more likely 
      than patients with STEMI or UA to have dyslipidemia.
FAU - Ralapanawa, Udaya
AU  - Ralapanawa U
AUID- ORCID: 0000-0002-7416-7984
AD  - Department of Medicine, University of Peradeniya, Peradeniya, Sri Lanka. 
      udayapralapanawa@yahoo.com.
FAU - Kumarasiri, Pallegoda Vithanage Ranjith
AU  - Kumarasiri PVR
AD  - Department of Community Medicine, University of Peradeniya, Peradeniya, Sri 
      Lanka.
FAU - Jayawickreme, Kushalee Poornima
AU  - Jayawickreme KP
AD  - Department of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.
FAU - Kumarihamy, Prabashini
AU  - Kumarihamy P
AD  - Teaching Hospital Peradeniya, Peradeniya, Sri Lanka.
FAU - Wijeratne, Yapa
AU  - Wijeratne Y
AD  - Teaching Hospital Peradeniya, Peradeniya, Sri Lanka.
FAU - Ekanayake, Madhushanka
AU  - Ekanayake M
AD  - Department of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.
FAU - Dissanayake, Chandira
AU  - Dissanayake C
AD  - Teaching Hospital Peradeniya, Peradeniya, Sri Lanka.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20191021
PL  - England
TA  - BMC Cardiovasc Disord
JT  - BMC cardiovascular disorders
JID - 100968539
SB  - IM
MH  - Acute Coronary Syndrome/diagnosis/*epidemiology
MH  - Adult
MH  - Age Factors
MH  - Aged
MH  - Alcoholism/diagnosis/epidemiology
MH  - Angina, Unstable/diagnosis/*epidemiology
MH  - Comorbidity
MH  - Cross-Sectional Studies
MH  - Dyslipidemias/epidemiology
MH  - Female
MH  - Humans
MH  - Hypertension/epidemiology
MH  - Male
MH  - Middle Aged
MH  - Non-ST Elevated Myocardial Infarction/diagnosis/*epidemiology
MH  - Risk Assessment
MH  - Risk Factors
MH  - ST Elevation Myocardial Infarction/diagnosis/*epidemiology
MH  - Sex Factors
MH  - Smoking/adverse effects/epidemiology
MH  - Sri Lanka/epidemiology
MH  - *Tertiary Care Centers
PMC - PMC6805431
OTO - NOTNLM
OT  - Acute coronary syndrome
OT  - Non-ST elevation myocardial infarction
OT  - ST elevation myocardial infarction
OT  - Sri Lanka
OT  - Unstable angina
COIS- The authors declare that they have no competing interests.
EDAT- 2019/10/23 06:00
MHDA- 2020/06/17 06:00
PMCR- 2019/10/21
CRDT- 2019/10/23 06:00
PHST- 2018/07/08 00:00 [received]
PHST- 2019/10/04 00:00 [accepted]
PHST- 2019/10/23 06:00 [entrez]
PHST- 2019/10/23 06:00 [pubmed]
PHST- 2020/06/17 06:00 [medline]
PHST- 2019/10/21 00:00 [pmc-release]
AID - 10.1186/s12872-019-1217-x [pii]
AID - 1217 [pii]
AID - 10.1186/s12872-019-1217-x [doi]
PST - epublish
SO  - BMC Cardiovasc Disord. 2019 Oct 21;19(1):229. doi: 10.1186/s12872-019-1217-x.