PMID- 31642279
OWN - NLM
STAT- MEDLINE
DCOM- 20191028
LR  - 20200108
IS  - 1872-2059 (Electronic)
IS  - 1000-8713 (Linking)
VI  - 37
IP  - 11
DP  - 2019 Nov 8
TI  - [Rapid screening and confirmation of 20 mycotoxins in grain products by ultrahigh 
      performance liquid chromatography- quadrupole/electrostatic field orbitrap high- 
      resolution mass spectrometry].
PG  - 1241-1248
LID - 10.3724/SP.J.1123.2019.03041 [doi]
AB  - A rapid method based on ultrahigh-performance liquid 
      chromatography-quadrupole/electrostatic field orbitrap high-resolution mass 
      spectrometry (UPLC-HRMS) was developed for the screening and confirmation of 20 
      mycotoxins in grain products. The samples were extracted with acetonitrile 
      containing 2% (v/v) formic acid, and the extracts were cleaned up on Captive 
      EMR-Lipid columns. The analytes were separated on a Thermo Hypersil Gold C(18) 
      column (100 mmx2.1 mm, 1.9 mum), and analyzed by UPLC-HRMS. The retention time and 
      accurate mass of the parent ion were used for fast screening in full scan mode, 
      while the accurate masses of the fragment ions were used for confirmation in the 
      two-stage threshold-triggered full mass scan mode. The results revealed that the 
      20 mycotoxins showed good linear relationships in their respective mass 
      concentration ranges. The correlation coefficients were not less than 0.99, and 
      the limits of quantitation (LOQs) ranged from 0.25 to 20 mug/kg. The recoveries of 
      the 20 mycotoxins in the sample ranged from 72.9% to 117.8% with the relative 
      standard deviations (RSDs) from 2.9% to 15.2% at three spiked levels (n=6). This 
      method has the advantages of high sensitivity and reliability, and is thus 
      suitable for the rapid screening and confirmation of 20 mycotoxins in grain 
      products.
FAU - Hu, Qiaoru
AU  - Hu Q
AD  - Yantai Customs Technology Center, Yantai 264000, China.
FAU - Cao, Peng
AU  - Cao P
AD  - Yantai Customs Technology Center, Yantai 264000, China.
FAU - Cong, Zhongxiao
AU  - Cong Z
AD  - Yantai Customs Technology Center, Yantai 264000, China.
FAU - Liang, Junni
AU  - Liang J
AD  - Yantai Customs Technology Center, Yantai 264000, China.
FAU - Sha, Meilan
AU  - Sha M
AD  - Yantai Customs Technology Center, Yantai 264000, China.
FAU - Li, Xiaoyu
AU  - Li X
AD  - Yantai Customs Technology Center, Yantai 264000, China.
FAU - Yin, Dalu
AU  - Yin D
AD  - Yantai Customs Technology Center, Yantai 264000, China.
FAU - Lu, Min
AU  - Lu M
AD  - Yantai Customs Technology Center, Yantai 264000, China.
LA  - chi
PT  - Journal Article
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Mycotoxins)
SB  - IM
MH  - Chromatography, High Pressure Liquid
MH  - Edible Grain/*chemistry/microbiology
MH  - Mass Spectrometry
MH  - Mycotoxins/*analysis
MH  - Reproducibility of Results
OTO - NOTNLM
OT  - confirmation
OT  - grain
OT  - high-resolution mass spectrometry (HRMS)
OT  - mycotoxins
OT  - rapid screening
OT  - ultrahigh performance liquid chromatography (UPLC)
EDAT- 2019/10/24 06:00
MHDA- 2019/10/29 06:00
CRDT- 2019/10/24 06:00
PHST- 2019/10/24 06:00 [entrez]
PHST- 2019/10/24 06:00 [pubmed]
PHST- 2019/10/29 06:00 [medline]
AID - 10.3724/SP.J.1123.2019.03041 [doi]
PST - ppublish
SO  - Se Pu. 2019 Nov 8;37(11):1241-1248. doi: 10.3724/SP.J.1123.2019.03041.