PMID- 31645501 OWN - NLM STAT- MEDLINE DCOM- 20191112 LR - 20200108 IS - 1672-7347 (Print) IS - 1672-7347 (Linking) VI - 44 IP - 9 DP - 2019 Sep 28 TI - [Successful simultaneous surgery for patient with insulinoma and parathyroid adenoma relevant to multiple endocrine neoplasia type 1: A case report]. PG - 1083-1088 LID - 10.11817/j.issn.1672-7347.2019.190601 [doi] AB - Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder. A 44-year-old man visited second Xiangya Hospital, Central South University due to hypoglycemia. He was eventually diagnosed as MEN1. A novel homozygous frameshift for c.640-643delCAGA (p.V215Mfs*13) of MEN1 gene was identified in the patient. After MDT (Multiple Disciplinary Team), open bilateral exploration with total parathyroidectomy and autotransplantation as well as partial pancreatectomy excision of all the macroscopic pancreatic tumors were performed at the same time. The patient recovered well. Individualized diagnosis and treatment are important for MEN1 patients. FAU - Hou, Baojian AU - Hou B AD - Department of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha 410011; Department of Metabolism and Endocrinology, Zhongshan Hospital in Hubei Province, Wuhan 430033, China. FAU - Tang, Weili AU - Tang W AD - Department of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha 410011; National Clinical Research Center for Metabolic Diseases, Changsha 410011, China. FAU - Su, Xin AU - Su X AD - Department of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha 410011; National Clinical Research Center for Metabolic Diseases, Changsha 410011, China. FAU - Liu, Wei AU - Liu W AD - Department of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha 410011; National Clinical Research Center for Metabolic Diseases, Changsha 410011, China. LA - chi PT - Case Reports PT - Journal Article PL - China TA - Zhong Nan Da Xue Xue Bao Yi Xue Ban JT - Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences JID - 101230586 SB - IM MH - Adult MH - Humans MH - *Insulinoma MH - Male MH - *Multiple Endocrine Neoplasia Type 1 MH - Pancreatic Neoplasms MH - *Parathyroid Neoplasms MH - Parathyroidectomy EDAT- 2019/10/28 06:00 MHDA- 2019/11/13 06:00 CRDT- 2019/10/25 06:00 PHST- 2019/10/25 06:00 [entrez] PHST- 2019/10/28 06:00 [pubmed] PHST- 2019/11/13 06:00 [medline] AID - 10.11817/j.issn.1672-7347.2019.190601 [doi] PST - ppublish SO - Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2019 Sep 28;44(9):1083-1088. doi: 10.11817/j.issn.1672-7347.2019.190601.