PMID- 31646328
OWN - NLM
STAT- MEDLINE
DCOM- 20191105
LR  - 20200108
IS  - 0371-0874 (Print)
IS  - 0371-0874 (Linking)
VI  - 71
IP  - 5
DP  - 2019 Oct 25
TI  - [Involvement of intrathecal activation of MrgC receptor in pathological pain and 
      morphine tolerance].
PG  - 741-748
AB  - Rodent MrgC receptor (Mas-related G-protein-coupled receptor subtype C) shares 
      65% sequence homology and similarities in terms of expression pattern and binding 
      profile with human Mas-related gene X receptor 1 (hMrgX1). Therefore, researchers 
      generally explore the role of hMrgX1 by studying the function of MrgC receptor. 
      Murine MrgC receptor is uniquely expressed in small-diameter neurons of dorsal 
      root ganglia (DRG) and trigeminal ganglia (TG), which is closely related to the 
      transmission process of pain. This review summarizes the analgesic effects of 
      intrathecal activation of MrgC receptors in pathological pain and morphine 
      tolerance.
FAU - Li, You-Ping
AU  - Li YP
AD  - College of Life Sciences, Fujian Normal University, Fujian Key Laboratory of 
      Developmental and Neuro Biology, Fuzhou 350117, China.
FAU - Jiang, Jian-Ping
AU  - Jiang JP
AD  - College of Life Sciences, Fujian Normal University, Fujian Key Laboratory of 
      Developmental and Neuro Biology, Fuzhou 350117, China. jjp@fjnu.edu.cn.
LA  - chi
PT  - Journal Article
PT  - Review
PL  - China
TA  - Sheng Li Xue Bao
JT  - Sheng li xue bao : [Acta physiologica Sinica]
JID - 20730130R
RN  - 0 (MrgC protein, mouse)
RN  - 0 (Peptide Fragments)
RN  - 0 (Receptors, G-Protein-Coupled)
RN  - 0 (mas-related gene-X1 receptor, human)
RN  - 76I7G6D29C (Morphine)
SB  - IM
MH  - Animals
MH  - *Drug Tolerance
MH  - Ganglia, Spinal
MH  - Humans
MH  - Mice
MH  - Morphine/*pharmacology
MH  - *Pain
MH  - Peptide Fragments
MH  - Rats
MH  - Rats, Sprague-Dawley
MH  - Receptors, G-Protein-Coupled/*physiology
MH  - Trigeminal Ganglion
EDAT- 2019/10/28 06:00
MHDA- 2019/11/07 06:00
CRDT- 2019/10/25 06:00
PHST- 2019/10/25 06:00 [entrez]
PHST- 2019/10/28 06:00 [pubmed]
PHST- 2019/11/07 06:00 [medline]
PST - ppublish
SO  - Sheng Li Xue Bao. 2019 Oct 25;71(5):741-748.