PMID- 31649597
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 1664-1078 (Print)
IS  - 1664-1078 (Electronic)
IS  - 1664-1078 (Linking)
VI  - 10
DP  - 2019
TI  - Auditory Deficits in Audiovisual Speech Perception in Adult Asperger's Syndrome: 
      fMRI Study.
PG  - 2286
LID - 10.3389/fpsyg.2019.02286 [doi]
LID - 2286
AB  - Audiovisual (AV) integration deficits have been proposed to underlie difficulties 
      in speech perception in Asperger's syndrome (AS). It is not known, if the AV 
      deficits are related to alterations in sensory processing at the level of 
      unisensory processing or at levels of conjoint multisensory processing. 
      Functional Magnetic-resonance images (MRI) was performed in 16 adult subjects 
      with AS and 16 healthy controls (HC) matched for age, gender, and verbal IQ as 
      they were exposed to disyllabic AV congruent and AV incongruent nouns. A simple 
      semantic categorization task was used to ensure subjects' attention to the 
      stimuli. The left auditory cortex (BA41) showed stronger activation in HC than in 
      subjects with AS with no interaction regarding AV congruency. This suggests that 
      alterations in auditory processing in unimodal low-level areas underlie AV speech 
      perception deficits in AS. Whether this is signaling a difficulty in the 
      deployment of attention remains to be demonstrated.
CI  - Copyright (c) 2019 Tietze, Hundertmark, Roy, Zerr, Sinke, Wiswede, Walter, Munte 
      and Szycik.
FAU - Tietze, Fabian-Alexander
AU  - Tietze FA
AD  - Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical 
      School, Hanover, Germany.
FAU - Hundertmark, Laura
AU  - Hundertmark L
AD  - Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical 
      School, Hanover, Germany.
FAU - Roy, Mandy
AU  - Roy M
AD  - Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical 
      School, Hanover, Germany.
AD  - Asklepios Clinic North - Ochsenzoll, Hamburg, Germany.
FAU - Zerr, Michael
AU  - Zerr M
AD  - Department of Psychosomatic Medicine and Psychotherapy, Hannover Medical School, 
      Hanover, Germany.
FAU - Sinke, Christopher
AU  - Sinke C
AD  - Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical 
      School, Hanover, Germany.
FAU - Wiswede, Daniel
AU  - Wiswede D
AD  - Institute of Psychology II, University of Lubeck, Lubeck, Germany.
AD  - Department of Neurology, University of Lubeck, Lubeck, Germany.
FAU - Walter, Martin
AU  - Walter M
AD  - Department of Psychiatry and Psychotherapy, University of Tubingen, Tubingen, 
      Germany.
FAU - Munte, Thomas F
AU  - Munte TF
AD  - Institute of Psychology II, University of Lubeck, Lubeck, Germany.
AD  - Department of Neurology, University of Lubeck, Lubeck, Germany.
FAU - Szycik, Gregor R
AU  - Szycik GR
AD  - Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical 
      School, Hanover, Germany.
LA  - eng
PT  - Journal Article
DEP - 20191010
PL  - Switzerland
TA  - Front Psychol
JT  - Frontiers in psychology
JID - 101550902
PMC - PMC6795762
OTO - NOTNLM
OT  - Asperger's syndrome
OT  - audiovisual
OT  - autism
OT  - fMRI
OT  - multisensory
OT  - speech
EDAT- 2019/10/28 06:00
MHDA- 2019/10/28 06:01
PMCR- 2019/10/10
CRDT- 2019/10/26 06:00
PHST- 2019/04/11 00:00 [received]
PHST- 2019/09/24 00:00 [accepted]
PHST- 2019/10/26 06:00 [entrez]
PHST- 2019/10/28 06:00 [pubmed]
PHST- 2019/10/28 06:01 [medline]
PHST- 2019/10/10 00:00 [pmc-release]
AID - 10.3389/fpsyg.2019.02286 [doi]
PST - epublish
SO  - Front Psychol. 2019 Oct 10;10:2286. doi: 10.3389/fpsyg.2019.02286. eCollection 
      2019.