PMID- 31659511
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200928
IS  - 2090-911X (Electronic)
IS  - 1110-2608 (Print)
IS  - 1110-2608 (Linking)
VI  - 71
IP  - 1
DP  - 2019 Aug 5
TI  - Assessment of left ventricular systolic function after VSD transcatheter device 
      closure using speckle tracking echocardiography.
PG  - 1
LID - 10.1186/s43044-019-0001-7 [doi]
LID - 1
AB  - BACKGROUND: This is a case-control study conducted on 30 children, 15 with VSD 
      who performed VSD transcatheter device closure (group A) and 15 controls of 
      matching age and gender (group B), in the period between September 2015 and 
      February 2018. We aimed to assess the global left ventricular (LV) systolic 
      function by 2D speckle tracking before and after ventricular septal defect (VSD) 
      transcatheter closure, in comparison to normal controls. All patients were 
      subjected to full history taking; general and cardiac examination; ECG; CXR; full 
      transthoracic echocardiographic examination, including VSD number, size, and 
      site; LV dimensions and volumes; estimated pulmonary artery pressure; right 
      ventricular size and function; left ventricular circumferential; and radial 
      strain imaging by 2D speckle tracking. Patients who had ventricular septal defect 
      closed were reassessed by transthoracic echocardiography after 3 months. RESULTS: 
      The study included 15 children with VSD: 3 males and 12 females; their age ranged 
      from 2 to 13 years; all had subaortic VSD except for 1 who had apical muscular 
      VSD: VSD size ranged from 3 to 8 mm; PFM coil was used to close defect in all 
      patients except for 2 patients who had an Amplatzer duct occlude I (ADOI) device, 
      and 1 patient needed an additional vascular plug after significant hemolysis. 
      Pre-procedurally, group A had a significantly higher LVEDD, LVESD, and LVEDV than 
      group B. Mean circumferential strain was significantly higher (more negative) in 
      group A than that in group B either pre- or post-procedure. Post-procedurally, 
      there was a significant decrease in circumferential strain (less negative) and a 
      significant increase in radial strain (more positive). CONCLUSION: Following 
      transcatheter VSD closure, there is a significant decrease in LV circumferential 
      strain and a significant increase in LV radial strain, which conclude a decrease 
      in LV volume overload with the improvement of its contractility.
FAU - Ali, Yasmin Abdelrazek
AU  - Ali YA
AD  - Ain Shams University, Cairo, 11528, Egypt. yasminabdelrazek@med.asu.edu.eg.
FAU - Hassan, Maryam Araby
AU  - Hassan MA
AD  - Ain Shams University, Cairo, 11528, Egypt.
FAU - El Fiky, Azza Abdallah
AU  - El Fiky AA
AD  - Ain Shams University, Cairo, 11528, Egypt.
LA  - eng
PT  - Journal Article
DEP - 20190805
PL  - Germany
TA  - Egypt Heart J
JT  - The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of 
      Cardiology
JID - 9106952
PMC - PMC6821406
OTO - NOTNLM
OT  - 2D strain
OT  - Speckle tracking
OT  - Transcatheter VSD closure
OT  - Ventricular septal defect
COIS- The authors declare that they have no competing interests.
EDAT- 2019/10/30 06:00
MHDA- 2019/10/30 06:01
PMCR- 2019/08/05
CRDT- 2019/10/30 06:00
PHST- 2019/05/27 00:00 [received]
PHST- 2019/06/21 00:00 [accepted]
PHST- 2019/10/30 06:00 [entrez]
PHST- 2019/10/30 06:00 [pubmed]
PHST- 2019/10/30 06:01 [medline]
PHST- 2019/08/05 00:00 [pmc-release]
AID - 10.1186/s43044-019-0001-7 [pii]
AID - 1 [pii]
AID - 10.1186/s43044-019-0001-7 [doi]
PST - epublish
SO  - Egypt Heart J. 2019 Aug 5;71(1):1. doi: 10.1186/s43044-019-0001-7.