PMID- 31666451
OWN - NLM
STAT- MEDLINE
DCOM- 20191206
LR  - 20191217
IS  - 1349-3299 (Electronic)
IS  - 1349-2365 (Linking)
VI  - 60
IP  - 6
DP  - 2019 Nov 30
TI  - Risk Factors for Moderate or More Residual Regurgitation in Patients with 
      Moderate Chronic Ischemic Mitral Regurgitation Undergoing Surgical 
      Revascularization Alone.
PG  - 1268-1275
LID - 10.1536/ihj.19-054 [doi]
AB  - Few reports have focused on which patients with moderate ischemic mitral 
      regurgitation (IMR) were not good candidates for coronary artery bypass grafting 
      (CABG) alone. This single-center study aimed to assess risk factors for moderate 
      or more residual regurgitation within two years after CABG alone for the 
      treatment of moderate chronic IMR to optimize the operation strategy and 
      prognosis.A total of 189 eligible patients were entered into a failure group (n = 
      108) or an improved group (n = 81) according to whether moderate or more residual 
      regurgitation occurred within two years after surgery. Baseline and surgical 
      characteristics were analyzed, and clinical outcomes were compared between 
      groups.Prior myocardial infarction (MI)/chronic myocardial ischemia and region 
      wall motion abnormality (anterior/inferior-posterior wall) were two independent 
      risk factors for moderate or more residual regurgitation, following CABG alone, 
      for the treatment of moderate chronic IMR (OR = 3.15, 95% CI 1.66-5.75, and OR = 
      2.45, 95% CI 1.36-4.84, respectively). During a median follow-up of 40 months, 
      compared with the improved group, the failure group was more likely to present 
      with New York Heart Association (NYHA) class III-IV and cardiac 
      re-hospitalization (57.4% versus 11.1%, P < 0.001, and 13.9% versus 4.9%, P = 
      0.043, respectively) and had worse cumulative survival (chi(2) = 4.259, log-rank P 
      = 0.039).Patients suffering from moderate chronic IMR secondary to prior MI 
      (rather than chronic ischemia) with anterior wall motion abnormalities (rather 
      than inferior-posterior wall motion abnormalities) may not be good candidates for 
      CABG alone, and may have a poor prognosis after CABG alone.
FAU - Ji, Qiang
AU  - Ji Q
AD  - Department of Cardiovascular Surgery, Zhongshan Hospital Fudan University.
FAU - Zhao, Yun
AU  - Zhao Y
AD  - Shanghai Institute of Cardiovascular Diseases.
FAU - Shen, JinQiang
AU  - Shen J
AD  - Department of Cardiovascular Surgery, Zhongshan Hospital Fudan University.
FAU - Wang, YuLin
AU  - Wang Y
AD  - Department of Cardiovascular Surgery, Zhongshan Hospital Fudan University.
FAU - Yang, Ye
AU  - Yang Y
AD  - Department of Cardiovascular Surgery, Zhongshan Hospital Fudan University.
FAU - Ding, WenJun
AU  - Ding W
AD  - Department of Cardiovascular Surgery, Zhongshan Hospital Fudan University.
FAU - Xia, LiMin
AU  - Xia L
AD  - Department of Cardiovascular Surgery, Zhongshan Hospital Fudan University.
FAU - Wang, ChunSheng
AU  - Wang C
AD  - Shanghai Institute of Cardiovascular Diseases.
LA  - eng
PT  - Journal Article
DEP - 20191031
PL  - Japan
TA  - Int Heart J
JT  - International heart journal
JID - 101244240
SB  - IM
MH  - Aged
MH  - Chronic Disease
MH  - *Coronary Artery Bypass
MH  - Female
MH  - Hospitalization
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Mitral Valve Insufficiency/*etiology/mortality/surgery
MH  - Myocardial Ischemia/*complications/mortality/*surgery
MH  - Patient Selection
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Survival Rate
MH  - Time Factors
MH  - Treatment Failure
OTO - NOTNLM
OT  - Myocardial infarction
OT  - Region wall motion abnormality
OT  - Residual mitral regurgitation
EDAT- 2019/11/02 06:00
MHDA- 2019/12/18 06:00
CRDT- 2019/11/01 06:00
PHST- 2019/11/02 06:00 [pubmed]
PHST- 2019/12/18 06:00 [medline]
PHST- 2019/11/01 06:00 [entrez]
AID - 10.1536/ihj.19-054 [doi]
PST - ppublish
SO  - Int Heart J. 2019 Nov 30;60(6):1268-1275. doi: 10.1536/ihj.19-054. Epub 2019 Oct 
      31.