PMID- 31668052
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 2005-6443 (Print)
IS  - 2092-6715 (Electronic)
IS  - 2005-6443 (Linking)
VI  - 40
IP  - 6
DP  - 2019 Nov
TI  - Association between Abdominal Obesity and Oxidative Stress in Korean Adults.
PG  - 395-398
LID - 10.4082/kjfm.18.0086 [doi]
AB  - BACKGROUND: Obesity causes several changes in the body and is associated with 
      both inflammation and oxidative stress. However, the relationship between 
      abdominal obesity, diacron-reactive oxygen metabolites (d-ROMs), and biological 
      antioxidant potential (BAP) levels in Korean adults has not yet been proved. The 
      aim of this study was to evaluate the association between d-ROMs, BAP levels, and 
      abdominal obesity in the Korean adult population using clinical data. METHODS: A 
      total of 2,367 individuals, aged 18-86 years, were identified from health 
      check-up examination records at a university hospital, between January 2015 and 
      August 2016. Clinical and biochemical parameters, including waist circumference, 
      lipid profile, alcohol drinking status, and smoking status, were investigated. 
      Oxidative stress levels, viz., d-ROM concentration and antioxidant capacity, 
      viz., BAP, were measured. RESULTS: Subjects with abdominal obesity presented 
      significantly higher levels of d-ROMs compared to those with a normal waist 
      circumference (P<0.001). After adjusting for age, sex, alcohol drinking status; 
      smoking status; and triglyceride, low-density lipoprotein levels were found to 
      have a significant positive correlation with abdominal obesity (P<0.001). BAP did 
      not significantly correlate with abdominal obesity. CONCLUSION: We observed a 
      positive association between abdominal obesity and d-ROM concentration. This 
      result indicates that abdominal obesity can increase oxidative stress and may 
      affect the pathways involved in obesity, such as the inflammatory pathway. Such 
      correlation analyses were helpful in revealing the causes, as well as methods to 
      reduce, oxidative stress.
FAU - Na, Im Jeong
AU  - Na IJ
AD  - Department of Family Practice and Community Health, Ajou University School of 
      Medicine, Suwon, Korea.
FAU - Park, Jae Sun
AU  - Park JS
AD  - Department of Family Practice and Community Health, Ajou University School of 
      Medicine, Suwon, Korea.
FAU - Park, Sat Byul
AU  - Park SB
AD  - Department of Family Practice and Community Health, Ajou University School of 
      Medicine, Suwon, Korea.
LA  - eng
PT  - Journal Article
DEP - 20191031
PL  - Korea (South)
TA  - Korean J Fam Med
JT  - Korean journal of family medicine
JID - 101502902
PMC - PMC6887768
OTO - NOTNLM
OT  - Abdominal Obesity
OT  - Biological Antioxidant Potential
OT  - Diacron-Reactive Oxygen Metabolites
OT  - Oxidative Stress
COIS- No potential conflict of interest relevant to this article was reported.
EDAT- 2019/11/02 06:00
MHDA- 2019/11/02 06:01
PMCR- 2019/11/01
CRDT- 2019/11/01 06:00
PHST- 2018/01/07 00:00 [received]
PHST- 2019/04/02 00:00 [accepted]
PHST- 2019/11/02 06:00 [pubmed]
PHST- 2019/11/02 06:01 [medline]
PHST- 2019/11/01 06:00 [entrez]
PHST- 2019/11/01 00:00 [pmc-release]
AID - kjfm.18.0086 [pii]
AID - kjfm-18-0086 [pii]
AID - 10.4082/kjfm.18.0086 [doi]
PST - ppublish
SO  - Korean J Fam Med. 2019 Nov;40(6):395-398. doi: 10.4082/kjfm.18.0086. Epub 2019 
      Oct 31.