PMID- 31668274 OWN - NLM STAT- MEDLINE DCOM- 20200724 LR - 20200724 IS - 1557-9832 (Electronic) IS - 0272-2712 (Linking) VI - 39 IP - 4 DP - 2019 Dec TI - Food Allergy Testing. PG - 625-642 LID - S0272-2712(19)30062-9 [pii] LID - 10.1016/j.cll.2019.07.009 [doi] AB - Although the gold standard for diagnosis of immunoglobulin E (IgE)-mediated food allergy is an oral food challenge, clinically relevant biomarkers of IgE sensitization, including serum-specific IgE and skin prick testing, can aid in diagnosis. Clinically useful values have been defined for individual foods. More recently, specific IgE to particular protein components has provided additional diagnostic value. In summary, food allergy diagnostics to evaluate IgE sensitization are clinically useful and continue to evolve to improve evaluation of IgE-mediated food allergies. CI - Copyright (c) 2019 Elsevier Inc. All rights reserved. FAU - LaHood, Nicole A AU - LaHood NA AD - Allergy and Immunology, Department of Medicine, Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, 55 Fruit Street, Cox 201, Boston, MA, USA. FAU - Patil, Sarita U AU - Patil SU AD - Department of Medicine, Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, 55 Fruit Street, Cox 201, Boston, MA, USA; Food Allergy Center, Massachusetts General Hospital for Children, Boston, MA, USA; Harvard Medical School, Boston, MA, USA. Electronic address: sarita.patil@mgh.harvard.edu. LA - eng GR - K23 AI121491/AI/NIAID NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural PT - Review DEP - 20191003 PL - United States TA - Clin Lab Med JT - Clinics in laboratory medicine JID - 8100174 RN - 37341-29-0 (Immunoglobulin E) SB - IM MH - Adolescent MH - Child MH - Child, Preschool MH - Food Hypersensitivity/blood/*diagnosis/physiopathology MH - Humans MH - Immunoglobulin E/blood MH - *Immunologic Tests MH - Infant MH - Sensitivity and Specificity MH - Skin Tests OTO - NOTNLM OT - Component testing OT - Food allergy OT - Immunoglobulin E OT - Oral food challenge OT - Skin testing EDAT- 2019/11/02 06:00 MHDA- 2020/07/25 06:00 CRDT- 2019/11/01 06:00 PHST- 2019/11/01 06:00 [entrez] PHST- 2019/11/02 06:00 [pubmed] PHST- 2020/07/25 06:00 [medline] AID - S0272-2712(19)30062-9 [pii] AID - 10.1016/j.cll.2019.07.009 [doi] PST - ppublish SO - Clin Lab Med. 2019 Dec;39(4):625-642. doi: 10.1016/j.cll.2019.07.009. Epub 2019 Oct 3.