PMID- 31671059 OWN - NLM STAT- MEDLINE DCOM- 20200319 LR - 20200319 IS - 1557-2501 (Electronic) IS - 1042-3931 (Linking) VI - 31 IP - 11 DP - 2019 Nov TI - Percutaneous Occlusion of Paravalvular Aortic Leaks: A Single-Center Experience Focused on Intracardiac Echocardiography. PG - 346-351 AB - OBJECTIVES: To describe our initial experience with an intracardiac echocardiography (ICE) for guidance of aortic percutaneous paravalvular leak occlusion (PPVLO) and to assess the outcomes after aortic PPVLO. BACKGROUND: PPVLO has emerged as an alternative to cardiac surgery for patients with symptomatic PVLs. ICE is an appealing alternative to transesophageal echocardiography (TEE) for guidance of percutaneous structural interventions, but experience with ICE for PPVLO guidance is limited. METHODS: We performed a retrospective analysis of all aortic PPVLOs performed in our center. The primary endpoints were technical and procedural success. Secondary endpoints included procedure-related complications, mortality, hospital admission due to heart failure, and improvement in New York Heart Association (NYHA) functional class. RESULTS: Ten aortic PPVLOs were included. ICE was used to guide 40% of the aortic PPVLOs. Median follow-up was 22 months (interquartile range, 3-33 months). Mortality was 22% and hospital admission due to heart failure was 33%. Technical and procedural success rates were 90% and 80%, respectively. Median NYHA class improved significantly after the procedure (P<.01). Success was achieved in all ICE cases without any procedure-related complications. CONCLUSION: In our initial experience with an ICE-guided approach for aortic PPVLO, technical and procedural success were achieved and there were no procedure-related complications. FAU - Ribeiro, Joana Maria AU - Ribeiro JM AD - Servico de Cardiologia, Centro Hospitalar e Universitario de Coimbra - Polo Hospital Geral, Quinta dos Vales, 3041-801, Coimbra, Portugal. joanamsbgribeiro@gmail.com. FAU - Paiva, Luis AU - Paiva L FAU - Teixeira, Rogerio AU - Teixeira R FAU - Puga, Luis AU - Puga L FAU - Lopes, Joao AU - Lopes J FAU - Sousa, Jose Pedro AU - Sousa JP FAU - Campos, Diana AU - Campos D FAU - Saleiro, Carolina AU - Saleiro C FAU - Costa, Marco AU - Costa M FAU - Goncalves, Lino AU - Goncalves L LA - eng PT - Journal Article PL - United States TA - J Invasive Cardiol JT - The Journal of invasive cardiology JID - 8917477 SB - IM MH - Aged MH - Aortic Valve/diagnostic imaging/*surgery MH - Cardiac Catheterization/*methods MH - Cardiac Surgical Procedures/*methods MH - Endoleak/diagnosis/*surgery MH - Female MH - Follow-Up Studies MH - Heart Valve Diseases/*surgery MH - Heart Valve Prosthesis Implantation/adverse effects MH - Humans MH - Intraoperative Period MH - Male MH - Middle Aged MH - Prosthesis Failure MH - Reoperation MH - Retrospective Studies MH - *Septal Occluder Device MH - Ultrasonography, Interventional/*methods OTO - NOTNLM OT - intracardiac echocardiography OT - paravalvular leak OT - percutaneous occlusion EDAT- 2019/11/02 06:00 MHDA- 2020/03/20 06:00 CRDT- 2019/11/01 06:00 PHST- 2019/11/01 06:00 [entrez] PHST- 2019/11/02 06:00 [pubmed] PHST- 2020/03/20 06:00 [medline] PST - ppublish SO - J Invasive Cardiol. 2019 Nov;31(11):346-351.