PMID- 31677201 OWN - NLM STAT- MEDLINE DCOM- 20201027 LR - 20201027 IS - 1440-1746 (Electronic) IS - 0815-9319 (Linking) VI - 35 IP - 6 DP - 2020 Jun TI - Long-term outcome of endoscopic ultrasound-guided pancreatic duct drainage using a fully covered self-expandable metal stent for pancreaticojejunal anastomosis stricture. PG - 994-1001 LID - 10.1111/jgh.14897 [doi] AB - BACKGROUND AND AIM: Endoscopic ultrasound-guided pancreatic duct drainage (EUS-PD) has been proposed for pancreatic duct obstruction after failure of endoscopic retrograde pancreatography. We evaluate the long-term outcomes of EUS-PD using a fully covered self-expandable metal stent (FCSEMS) for pancreaticojejunal anastomosis (PJA) strictures following Whipple procedures. METHODS: Twenty-three patients with PJA strictures underwent EUS-PD according to the findings of EUS-guided pancreatogram and the passage of the guidewire through PJA stricture (complete vs partial stricture) after failure of endoscopic retrograde pancreatography. Technical and clinical success, adverse events (AEs), and long-term outcomes were assessed. RESULTS: Technical and clinical success was achieved in all patients. The complete and partial strictures were 11 and 12, respectively. The direct transanastomotic and transmural plastic stenting in partial PJA stricture was successful in only three patients (13%). Therefore, 20 patients underwent EUS-guided transmural FCSEMS placement during the initial attempt. Early AEs, including abdominal pain (n = 3) and peripancreatic fluid collection (n = 1), occurred in four patients (17.4%). During the follow-up periods (median, 27.2 months; interquartile range [IQR], 18.7-40.6), five patients (21.7%) developed late AEs, including asymptomatic stent fracture at the gastric end (n = 3), asymptomatic stent migration (n = 1), and stent occlusion (n = 1). The total duration of stent placement was 27.2 months (IQR, 18.7-40.6), and the median number of stent revision was 2 (IQR, 1-2). CONCLUSIONS: In terms of safety and efficacy, EUS-PD with an FCSEMS showed favorable success and acceptable AEs rate and durable long-term outcomes. CI - (c) 2019 Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd. FAU - Oh, Dongwook AU - Oh D AUID- ORCID: 0000-0002-6084-0138 AD - Division of Gastroenterology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. FAU - Park, Do Hyun AU - Park DH AD - Division of Gastroenterology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. FAU - Song, Tae Jun AU - Song TJ AD - Division of Gastroenterology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. FAU - Lee, Sang Soo AU - Lee SS AD - Division of Gastroenterology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. FAU - Seo, Dong-Wan AU - Seo DW AD - Division of Gastroenterology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. FAU - Lee, Sung Koo AU - Lee SK AD - Division of Gastroenterology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. FAU - Kim, Myung-Hwan AU - Kim MH AD - Division of Gastroenterology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. LA - eng PT - Journal Article DEP - 20191210 PL - Australia TA - J Gastroenterol Hepatol JT - Journal of gastroenterology and hepatology JID - 8607909 SB - IM MH - Aged MH - Cholangiopancreatography, Endoscopic Retrograde/adverse effects MH - Constriction, Pathologic/etiology/surgery MH - Drainage/*methods MH - Endoscopy, Digestive System/*methods MH - Endosonography/*methods MH - Female MH - Humans MH - Male MH - Middle Aged MH - Pancreatic Ducts/*pathology/*surgery MH - Pancreaticojejunostomy/*adverse effects/methods MH - Retrospective Studies MH - *Self Expandable Metallic Stents MH - Time Factors MH - Treatment Outcome OTO - NOTNLM OT - Whipple procedures OT - endoscopic ultrasound-guided pancreatic duct drainage OT - fully covered self-expandable metal stents OT - long-term outcomes OT - pancreatic ductal obstruction EDAT- 2019/11/05 06:00 MHDA- 2020/10/28 06:00 CRDT- 2019/11/03 06:00 PHST- 2019/04/05 00:00 [received] PHST- 2019/09/17 00:00 [revised] PHST- 2019/10/08 00:00 [accepted] PHST- 2019/11/05 06:00 [pubmed] PHST- 2020/10/28 06:00 [medline] PHST- 2019/11/03 06:00 [entrez] AID - 10.1111/jgh.14897 [doi] PST - ppublish SO - J Gastroenterol Hepatol. 2020 Jun;35(6):994-1001. doi: 10.1111/jgh.14897. Epub 2019 Dec 10.