PMID- 31685902
OWN - NLM
STAT- MEDLINE
DCOM- 20201029
LR  - 20210110
IS  - 2045-2322 (Electronic)
IS  - 2045-2322 (Linking)
VI  - 9
IP  - 1
DP  - 2019 Nov 4
TI  - Radiation dose and image quality of high-pitch emergency abdominal CT in obese 
      patients using third-generation dual-source CT (DSCT).
PG  - 15877
LID - 10.1038/s41598-019-52454-5 [doi]
LID - 15877
AB  - In this third-generation dual-source CT (DSCT) study, we retrospectively 
      investigated radiation dose and image quality of portal-venous high-pitch 
      emergency CT in 60 patients (28 female, mean age 56 years) with a body mass index 
      (BMI) >/= 30 kg/m(2). Patients were dichotomized in groups A (median BMI 
      31.5 kg/m(2); n = 33) and B (36.8 kg/m(2); n = 27). Volumetric CT dose index 
      (CTDI(vol)), size-specific dose estimate (SSDE), dose length product (DLP) and 
      effective dose (ED) were assessed. Contrast-to-noise ratio (CNR) and 
      dose-independent figure-of-merit (FOM) CNR were calculated. Subjective image 
      quality was assessed using a five-point scale. Mean values of CTDI(vol), SSDE as 
      well as normalized DLP and ED were 7.6 +/- 1.8 mGy, 8.0 +/- 1.8 mGy, 304 +/- 74 
      mGy * cm and 5.2 +/- 1.3 mSv for group A, and 12.6 +/- 3.7 mGy, 11.0 +/- 2.6 mGy, 
      521 +/- 157 mGy * cm and 8.9 +/- 2.7 mSv for group B (p < 0.001). CNR of the liver 
      and spleen as well as each calculated FOM CNR were significantly higher in group 
      A (p < 0.001). Subjective image quality was good in both groups. In conclusion, 
      third-generation abdominal high-pitch emergency DSCT yields good image quality in 
      obese patients. Radiation dose increases in patients with a BMI > 36.8 kg/m(2).
FAU - Forbrig, Robert
AU  - Forbrig R
AUID- ORCID: 0000-0002-1054-1463
AD  - Institute of Neuroradiology, University Hospital, LMU Munich, Munich, Germany. 
      robert.forbrig@med.uni-muenchen.de.
FAU - Ingrisch, Michael
AU  - Ingrisch M
AD  - Department of Radiology, University Hospital, LMU Munich, Munich, Germany.
FAU - Stahl, Robert
AU  - Stahl R
AD  - Institute of Neuroradiology, University Hospital, LMU Munich, Munich, Germany.
AD  - Department of Radiology, University Hospital, LMU Munich, Munich, Germany.
FAU - Winter, Katharina Stella
AU  - Winter KS
AD  - Department of Radiology, University Hospital, LMU Munich, Munich, Germany.
FAU - Reiser, Maximilian
AU  - Reiser M
AD  - Department of Radiology, University Hospital, LMU Munich, Munich, Germany.
FAU - Trumm, Christoph G
AU  - Trumm CG
AD  - Institute of Neuroradiology, University Hospital, LMU Munich, Munich, Germany.
AD  - Institute for Diagnostic and Interventional Radiology, Neuroradiology and Nuclear 
      Medicine, Munchen Klinik Harlaching, Munich, Germany.
LA  - eng
PT  - Journal Article
DEP - 20191104
PL  - England
TA  - Sci Rep
JT  - Scientific reports
JID - 101563288
RN  - 0 (Contrast Media)
SB  - IM
MH  - Abdomen/*diagnostic imaging
MH  - Adult
MH  - Body Mass Index
MH  - Contrast Media/chemistry
MH  - Female
MH  - Humans
MH  - Image Enhancement
MH  - Male
MH  - Middle Aged
MH  - Obesity/*pathology
MH  - Radiation Dosage
MH  - Retrospective Studies
MH  - Signal-To-Noise Ratio
MH  - Tomography, X-Ray Computed/*methods
PMC - PMC6828752
COIS- The authors declare no competing interests.
EDAT- 2019/11/07 06:00
MHDA- 2020/10/30 06:00
PMCR- 2019/11/04
CRDT- 2019/11/06 06:00
PHST- 2019/01/09 00:00 [received]
PHST- 2019/10/17 00:00 [accepted]
PHST- 2019/11/06 06:00 [entrez]
PHST- 2019/11/07 06:00 [pubmed]
PHST- 2020/10/30 06:00 [medline]
PHST- 2019/11/04 00:00 [pmc-release]
AID - 10.1038/s41598-019-52454-5 [pii]
AID - 52454 [pii]
AID - 10.1038/s41598-019-52454-5 [doi]
PST - epublish
SO  - Sci Rep. 2019 Nov 4;9(1):15877. doi: 10.1038/s41598-019-52454-5.