PMID- 31688552
OWN - NLM
STAT- MEDLINE
DCOM- 20200430
LR  - 20210211
IS  - 1537-1948 (Electronic)
IS  - 0025-7079 (Linking)
VI  - 58
IP  - 1
DP  - 2020 Jan
TI  - Adverse Events Among Hospitalized Critically Ill Patients: A Retrospective Cohort 
      Study.
PG  - 38-44
LID - 10.1097/MLR.0000000000001238 [doi]
AB  - OBJECTIVE: The objective of this study was to estimate the frequency and type of 
      adverse events (AEs) among critically ill patients and identify patient and 
      hospital factors associated with AEs and clinical and health care utilization 
      consequences of AEs. MATERIALS AND METHODS: This retrospective cohort study 
      includes patients admitted to 30 intensive care units (ICUs) in Alberta, Canada 
      from May 2014 to April 2017. The main outcome was AEs derived from validated 
      ICD-10, Canadian code algorithms for 18 AEs. Estimates of the proportion and rate 
      of AEs are presented. The association between documented AEs and patient (eg, 
      age, sex, comorbidities) and hospital (eg, ICU site and type, length of stay, 
      readmission) variables are described using regression methods. RESULTS: Of 49,447 
      hospital admissions with admission to ICU, >/=1 AEs were documented in 12,549 (25%) 
      admissions. The most common AEs were respiratory complications (10%) and 
      hospital-acquired infections (9%). AEs were associated with having >/=2 
      comorbidities [odds ratio (OR)=1.4, 95% confidence interval (CI)=1.3-1.4], being 
      admitted to the ICU from the operating room or another hospital ward (OR=1.8, 95% 
      CI=1.7-2.0 and OR=2.7, 95% CI=2.5-3.0, respectively) and being readmitted to ICU 
      during their hospital stay (OR=4.8, 95% CI=4.7-5.6). Patients with an AE stayed 
      5.4 days longer in ICU (95% CI=5.2-5.6 d, P<0.001), 18.2 days longer in hospital 
      (95% CI=17.7-18.8 d, P<0.001) and had increased odds of hospital mortality 
      (OR=1.5, 95% CI=1.4-1.6) than those without an AE. CONCLUSIONS: AEs are common 
      among critically ill patients and certain factors are associated with AEs. 
      Documented AEs are associated with longer stays and increased mortality.
FAU - Sauro, Khara M
AU  - Sauro KM
AD  - Departments of Critical Care Medicine.
AD  - Community Health Sciences.
AD  - O'Brien Institute of Public Health, Cumming School of Medicine, University of 
      Calgary.
AD  - Alberta Health Services, Calgary, AB, Canada.
FAU - Soo, Andrea
AU  - Soo A
AD  - Departments of Critical Care Medicine.
FAU - Quan, Hude
AU  - Quan H
AD  - Community Health Sciences.
AD  - O'Brien Institute of Public Health, Cumming School of Medicine, University of 
      Calgary.
AD  - Alberta Health Services, Calgary, AB, Canada.
FAU - Stelfox, Henry T
AU  - Stelfox HT
AD  - Departments of Critical Care Medicine.
AD  - Community Health Sciences.
AD  - O'Brien Institute of Public Health, Cumming School of Medicine, University of 
      Calgary.
AD  - Alberta Health Services, Calgary, AB, Canada.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Med Care
JT  - Medical care
JID - 0230027
SB  - IM
MH  - Aged
MH  - Alberta/epidemiology
MH  - Critical Care/*statistics & numerical data
MH  - Critical Care Outcomes
MH  - Critical Illness/*mortality
MH  - Cross Infection/mortality
MH  - Databases, Factual
MH  - Female
MH  - Hospital Mortality
MH  - Hospitalization/*statistics & numerical data
MH  - Hospitals/statistics & numerical data
MH  - Humans
MH  - Intensive Care Units/*statistics & numerical data
MH  - Male
MH  - Middle Aged
MH  - Odds Ratio
MH  - Patient Acceptance of Health Care/*statistics & numerical data
MH  - Regression Analysis
MH  - Retrospective Studies
EDAT- 2019/11/07 06:00
MHDA- 2020/05/01 06:00
CRDT- 2019/11/06 06:00
PHST- 2019/11/07 06:00 [pubmed]
PHST- 2020/05/01 06:00 [medline]
PHST- 2019/11/06 06:00 [entrez]
AID - 00005650-202001000-00007 [pii]
AID - 10.1097/MLR.0000000000001238 [doi]
PST - ppublish
SO  - Med Care. 2020 Jan;58(1):38-44. doi: 10.1097/MLR.0000000000001238.