PMID- 31689232
OWN - NLM
STAT- MEDLINE
DCOM- 20200511
LR  - 20200511
IS  - 2191-0251 (Electronic)
IS  - 0334-018X (Linking)
VI  - 32
IP  - 12
DP  - 2019 Dec 18
TI  - Once-weekly supervised combined training improves neurocognitive and 
      psychobehavioral outcomes in young patients with type 1 diabetes mellitus.
PG  - 1341-1350
LID - 10.1515/jpem-2019-0120 [doi]
AB  - Background Previous studies investigating the beneficial effects of exercise in 
      type 1 diabetes mellitus (T1DM) are relatively insufficient compared to studies 
      on type 2 diabetes mellitus (T2DM), due to the fear of hypoglycemia. Recently, 
      several researchers have reported that combined aerobic and resistance exercise 
      prevents hypoglycemia during and after exercise. Furthermore, exercise has been 
      shown to have beneficial effects on the psychological status of patients with 
      various diseases. The aim of this study was to evaluate the effect of combined 
      aerobic and resistance exercise in adolescents with T1DM. Methods Thirty-five 
      type 1 diabetic patients were enrolled, and subjects were divided into either an 
      exercise group or a control group. Thirty patients (20 patients in the exercise 
      group, 10 patients in the control group) completed the study. The exercise 
      program was performed for 1 h at a time, once a week, for 12 weeks. Study 
      parameters were evaluated at baseline and 3 months after baseline evaluation. 
      Results Combined aerobic and resistance exercise better controlled the body mass 
      index (BMI), and also improved maximum muscular strength and maximum exercise 
      intensity. On psychological tests, subjects' attention and quality of life showed 
      improving tendency, while their stress and behavioral problems diminished. The 
      number of exercise events increased in the training group, while the daily total 
      insulin dose and glycated hemoglobin (HbA1c) level showed no significant changes. 
      Conclusions A 12-week structured exercise program consisting of aerobic and 
      resistance exercises improves cardiovascular, neurocognitive and psychobehavioral 
      functions, and positively helps lifestyle modification in patients with T1DM.
FAU - Suh, Junghwan
AU  - Suh J
AUID- ORCID: 0000-0002-2092-2585
AD  - Department of Pediatrics, Severance Children's Hospital, Endocrine Research 
      Institute, Yonsei University College of Medicine, Seoul, Korea.
FAU - Choi, Han Saem
AU  - Choi HS
AD  - Department of Pediatrics, Severance Children's Hospital, Endocrine Research 
      Institute, Yonsei University College of Medicine, Seoul, Korea.
FAU - Kwon, Ahreum
AU  - Kwon A
AD  - Department of Pediatrics, Severance Children's Hospital, Endocrine Research 
      Institute, Yonsei University College of Medicine, Seoul, Korea.
FAU - Chae, Hyun Wook
AU  - Chae HW
AD  - Department of Pediatrics, Severance Children's Hospital, Endocrine Research 
      Institute, Yonsei University College of Medicine, Seoul, Korea.
FAU - Eom, Soyong
AU  - Eom S
AD  - Epilepsy Research Institute, Yonsei University College of Medicine, Seoul, Korea.
FAU - Kim, Ho-Seong
AU  - Kim HS
AD  - Department of Pediatrics, Severance Children's Hospital, Endocrine Research 
      Institute, Yonsei University College of Medicine, Seoul, Korea.
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - J Pediatr Endocrinol Metab
JT  - Journal of pediatric endocrinology & metabolism : JPEM
JID - 9508900
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Body Mass Index
MH  - Case-Control Studies
MH  - Child
MH  - Diabetes Mellitus, Type 1/*therapy
MH  - Exercise Therapy/*methods
MH  - Female
MH  - Follow-Up Studies
MH  - *Health Behavior
MH  - Humans
MH  - Male
MH  - Neurocognitive Disorders/*prevention & control
MH  - Prognosis
MH  - Resistance Training
MH  - Stress, Psychological/*prevention & control
MH  - Young Adult
OTO - NOTNLM
OT  - adolescent
OT  - aerobic exercise
OT  - resistance training
OT  - type 1 diabetes mellitus
EDAT- 2019/11/07 06:00
MHDA- 2020/05/12 06:00
CRDT- 2019/11/06 06:00
PHST- 2019/03/11 00:00 [received]
PHST- 2019/08/28 00:00 [accepted]
PHST- 2019/11/07 06:00 [pubmed]
PHST- 2020/05/12 06:00 [medline]
PHST- 2019/11/06 06:00 [entrez]
AID - /j/jpem.ahead-of-print/jpem-2019-0120/jpem-2019-0120.xml [pii]
AID - 10.1515/jpem-2019-0120 [doi]
PST - ppublish
SO  - J Pediatr Endocrinol Metab. 2019 Dec 18;32(12):1341-1350. doi: 
      10.1515/jpem-2019-0120.