PMID- 31691539
OWN - NLM
STAT- MEDLINE
DCOM- 20200827
LR  - 20231019
IS  - 2051-817X (Electronic)
IS  - 2051-817X (Linking)
VI  - 7
IP  - 21
DP  - 2019 Nov
TI  - Changes in the blood redox balance during a simulated duathlon race and its 
      relationship with athletic performance.
PG  - e14277
LID - 10.14814/phy2.14277 [doi]
LID - e14277
AB  - The duathlon is an endurance multisport event that consists of sequential 
      running, cycling, and further running. Imbalance in the redox homeostasis is 
      associated with fatigued status and underperformance in various sports; however, 
      there are no corresponding reports regarding the duathlon. The purpose of this 
      study was to examine the changes in the blood redox balance during a simulated 
      duathlon race and to determine the relationship between performance and the redox 
      balance. Eight male triathletes participated in a simulated race, consisting of a 
      5-km run, 30 km cycling, and a further 5-km run, with 5 min rest between two 
      parts to collect the blood samples. The serum levels of reactive oxygen 
      metabolites (d-ROMs) and biological antioxidant potential (BAP) were measured and 
      BAP/d-ROMs ratio and oxidative stress index (OSI) were calculated. The d-ROMs 
      levels after the first Run were significantly increased compared with the levels 
      observed before the race. Moreover, BAP levels increased significantly over the 
      race. The BAP/d-ROMs ratio also gradually increased through the race, while the 
      OSI was gradually decreased. In addition, a significant relationship was observed 
      only between d-ROMs levels after the first Run and the first Run performance. 
      These results suggest that the redox balance shifts toward reduction 
      (antioxidation) during the duathlon race and increased oxidant potential levels 
      are negatively correlated with performance in the early stages of the race.
CI  - (c) 2019 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on 
      behalf of The Physiological Society and the American Physiological Society.
FAU - Tsuzuki, Takamasa
AU  - Tsuzuki T
AUID- ORCID: 0000-0002-0241-1183
AD  - Faculty of Pharmacy, Meijo University, Nagoya, Japan.
AD  - Graduate School of Health and Sports Science, Juntendo University, Inzai, Japan.
FAU - Tsukioka, Kei
AU  - Tsukioka K
AD  - Graduate School of Health and Sports Science, Juntendo University, Inzai, Japan.
FAU - Naito, Hisashi
AU  - Naito H
AD  - Graduate School of Health and Sports Science, Juntendo University, Inzai, Japan.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Physiol Rep
JT  - Physiological reports
JID - 101607800
RN  - 0 (Antioxidants)
RN  - 0 (Biomarkers)
RN  - 0 (Reactive Oxygen Species)
RN  - S88TT14065 (Oxygen)
SB  - IM
MH  - Adult
MH  - Antioxidants
MH  - Athletic Performance/*physiology
MH  - Biomarkers/blood
MH  - Blood/*metabolism
MH  - Exercise/*physiology
MH  - Humans
MH  - Male
MH  - Oxidation-Reduction
MH  - Oxidative Stress
MH  - Oxygen/blood
MH  - Reactive Oxygen Species/blood
MH  - Young Adult
PMC - PMC6832001
OTO - NOTNLM
OT  - Duathlon
OT  - oxidative stress
OT  - performance
OT  - simulated race
COIS- No conflict of interests, financial or otherwise, is declared by the authors.
EDAT- 2019/11/07 06:00
MHDA- 2020/08/28 06:00
PMCR- 2019/11/06
CRDT- 2019/11/07 06:00
PHST- 2019/05/22 00:00 [received]
PHST- 2019/09/05 00:00 [revised]
PHST- 2019/10/06 00:00 [accepted]
PHST- 2019/11/07 06:00 [entrez]
PHST- 2019/11/07 06:00 [pubmed]
PHST- 2020/08/28 06:00 [medline]
PHST- 2019/11/06 00:00 [pmc-release]
AID - PHY214277 [pii]
AID - 10.14814/phy2.14277 [doi]
PST - ppublish
SO  - Physiol Rep. 2019 Nov;7(21):e14277. doi: 10.14814/phy2.14277.