PMID- 31695526
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220411
IS  - 1179-156X (Print)
IS  - 1179-156X (Electronic)
IS  - 1179-156X (Linking)
VI  - 11
DP  - 2019
TI  - A qualitative study of patient perspectives related to glucocorticoid therapy in 
      polymyalgia rheumatica and giant cell arteritis.
PG  - 189-198
LID - 10.2147/OARRR.S213964 [doi]
AB  - OBJECTIVE: To determine patient experiences of glucocorticoid (GC) therapy in 
      polymyalgia rheumatica (PMR) and giant cell arteritis (GCA). METHODS: Patients 
      with a diagnosis of PMR or GCA were invited to participate in this qualitative 
      study that used focus groups to explore: symptoms onset, process of diagnosis, 
      treatment, adverse effects (AEs), and ongoing condition/s management. Data were 
      transcribed verbatim and a "framework" approach was used for analysis and 
      interpretation. RESULTS: Fourteen patients participated. Weight gain, changes in 
      face and neck shape, and bruising were commonly reported and impacts of these AEs 
      on quality of life were highlighted. Dealing with uncertainties associated with 
      long-term experiences of the condition/s and cycles of GC treatment were raised 
      as were workload demands for patients in managing both the condition and other 
      people's expectations and recommendations related to GC therapy. CONCLUSION: 
      These findings demonstrate that the patient experience of GC use is poorly 
      captured by usual physician monitoring for GC AEs. These findings suggest that 
      development of a patient-reported outcome instrument for inflammatory conditions 
      treated with GCs is required.
CI  - (c) 2019 Hoon et al.
FAU - Hoon, Elizabeth
AU  - Hoon E
AD  - School of Public Health, University of Adelaide, Adelaide, SA 5000, Australia.
FAU - Ruediger, Carlee
AU  - Ruediger C
AD  - Adelaide Medical School, University of Adelaide, Adelaide, SA 5000, Australia.
AD  - Rheumatology Unit, The Queen Elizabeth Hospital, Woodville, SA 5011, Australia.
FAU - Gill, Tiffany K
AU  - Gill TK
AD  - Adelaide Medical School, University of Adelaide, Adelaide, SA 5000, Australia.
FAU - Black, Rachel J
AU  - Black RJ
AD  - Adelaide Medical School, University of Adelaide, Adelaide, SA 5000, Australia.
AD  - Rheumatology Unit, The Royal Adelaide Hospital, Adelaide, SA 5000, Australia.
FAU - Hill, Catherine L
AU  - Hill CL
AD  - Adelaide Medical School, University of Adelaide, Adelaide, SA 5000, Australia.
AD  - Rheumatology Unit, The Queen Elizabeth Hospital, Woodville, SA 5011, Australia.
AD  - Rheumatology Unit, The Royal Adelaide Hospital, Adelaide, SA 5000, Australia.
LA  - eng
PT  - Journal Article
DEP - 20190829
PL  - New Zealand
TA  - Open Access Rheumatol
JT  - Open access rheumatology : research and reviews
JID - 101688698
PMC - PMC6718238
OTO - NOTNLM
OT  - adverse effects
OT  - giant cell arteritis
OT  - glucocorticoid therapy
OT  - patient experience
OT  - polymyalgia rheumatica
COIS- Through the data collection and analysis period of this study, Elizabeth Hoon was 
      supported by an Arthritis South Australian Florey Research Fellowship.  Tiffany K 
      Gill reports grants from Arthritis Australia, during the conduct of the study. 
      The authors report no other conflicts of interest in this work.
EDAT- 2019/11/07 06:00
MHDA- 2019/11/07 06:01
PMCR- 2019/08/29
CRDT- 2019/11/08 06:00
PHST- 2019/04/30 00:00 [received]
PHST- 2019/07/25 00:00 [accepted]
PHST- 2019/11/08 06:00 [entrez]
PHST- 2019/11/07 06:00 [pubmed]
PHST- 2019/11/07 06:01 [medline]
PHST- 2019/08/29 00:00 [pmc-release]
AID - 213964 [pii]
AID - 10.2147/OARRR.S213964 [doi]
PST - epublish
SO  - Open Access Rheumatol. 2019 Aug 29;11:189-198. doi: 10.2147/OARRR.S213964. 
      eCollection 2019.