PMID- 31695862
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220411
IS  - 2040-6223 (Print)
IS  - 2040-6231 (Electronic)
IS  - 2040-6223 (Linking)
VI  - 10
DP  - 2019
TI  - The responsiveness of the Manchester Chronic Obstructive Pulmonary Disease 
      Fatigue Scale to pulmonary rehabilitation.
PG  - 2040622319882206
LID - 10.1177/2040622319882206 [doi]
LID - 2040622319882206
AB  - BACKGROUND: We examined the responsiveness of the Manchester Chronic Obstructive 
      Pulmonary Disease (COPD) Fatigue Scale (MCFS) in patients with COPD following 
      8 weeks of pulmonary rehabilitation (PR). METHODS: Patients (n = 273) with 
      clinically stable COPD completed 8 weeks of outpatient multidisciplinary PR, 
      comprising 2 h (1 h exercise and 1 h education) weekly. Anxiety, exercise 
      capacity, quality of life, dyspnea, fatigue were measured pre- and post-PR, 
      utilizing the Anxiety Inventory for Respiratory Disease (AIR), Incremental 
      Shuttle Walk Test (ISWT), St. George's Respiratory Questionnaire (SGRQ), and 
      modified Medical Research Council (mMRC) scale and MCFS, respectively. RESULTS: 
      The mean (SD) age of participants was 72 (8) years, and 50% were women. Total 
      MCFS score fell after PR mean (95% confidence interval) -4.89 (-7.90 to -3.79) as 
      did domain scores: physical -1.89 (-2.33 to -1.46), cognition -1.37 (-1.65 to 
      -1.09), and psychosocial -1.62 (-2.00 to -1.62). Total MCFS effect size (ES) was 
      0.55; and for domains, physical was 0.52, cognition was 0.59, and psychosocial 
      was 0.51. The ES for AIR was 0.30, mMRC was 0.38, SGRQ was 0.66, and ISWT was 
      1.19. MCFS changes correlated with changes in both SGRQ (p < 0.002) and AIR 
      (p < 0.004), but not ISWT (p = 0.30) or mMRC (p = 0.18). The AIR, SGRQ, mMRC, and 
      ISWT all improved after PR (all, p < 0.001). CONCLUSION: The MCFS scale is a 
      valid and responsive scale to measure fatigue in patients with COPD after 
      pulmonary rehabilitation.
CI  - (c) The Author(s), 2019.
FAU - Yohannes, Abebaw Mengistu
AU  - Yohannes AM
AUID- ORCID: 0000-0002-8341-270X
AD  - Department of Physiotherapy, School of Behavioral and Applied Sciences, Azusa 
      Pacific University, 701 East Foothill Boulevard, Azusa, CA 91702-7000, USA.
FAU - Dryden, Sheila
AU  - Dryden S
AD  - Lytham St. Annes Primary Care Center, Lancashire, UK.
FAU - Hanania, Nicola Alexander
AU  - Hanania NA
AUID- ORCID: 0000-0003-3087-9530
AD  - Section of Pulmonary and Critical Care Medicine, Baylor College of Medicine, 
      Houston, TX, USA.
LA  - eng
PT  - Journal Article
DEP - 20191029
PL  - United States
TA  - Ther Adv Chronic Dis
JT  - Therapeutic advances in chronic disease
JID - 101532140
PMC - PMC6820178
OTO - NOTNLM
OT  - COPD
OT  - anxiety
OT  - dyspnea
OT  - fatigue
OT  - pulmonary rehabilitation
OT  - quality of life
COIS- Conflict of interest statement: The author(s) declared the following potential 
      conflicts of interest with respect to the research, authorship, and/or 
      publication of this article: AMY and SD have no conflicts of interest. NAH has 
      received consultation fees and expenses paid for serving on advisory boards or as 
      a consultant from Astra Zeneca, GSK, Boehringer Ingelheim, Mylan, Sunovion, 
      Sanofi Genzyme, and Novartis. His institution received research grant support on 
      his behalf from Astra Zeneca, GSK, and Boehringer Ingelheim.
EDAT- 2019/11/07 06:00
MHDA- 2019/11/07 06:01
PMCR- 2019/10/29
CRDT- 2019/11/08 06:00
PHST- 2019/02/15 00:00 [received]
PHST- 2019/09/04 00:00 [accepted]
PHST- 2019/11/08 06:00 [entrez]
PHST- 2019/11/07 06:00 [pubmed]
PHST- 2019/11/07 06:01 [medline]
PHST- 2019/10/29 00:00 [pmc-release]
AID - 10.1177_2040622319882206 [pii]
AID - 10.1177/2040622319882206 [doi]
PST - epublish
SO  - Ther Adv Chronic Dis. 2019 Oct 29;10:2040622319882206. doi: 
      10.1177/2040622319882206. eCollection 2019.