PMID- 31697954
OWN - NLM
STAT- MEDLINE
DCOM- 20200227
LR  - 20240328
IS  - 1527-9995 (Electronic)
IS  - 0090-4295 (Print)
IS  - 0090-4295 (Linking)
VI  - 136
DP  - 2020 Feb
TI  - Kidney Stone History and Adverse Outcomes After Percutaneous Coronary 
      Intervention.
PG  - 75-81
LID - S0090-4295(19)30929-X [pii]
LID - 10.1016/j.urology.2019.10.009 [doi]
AB  - OBJECTIVE: To determine whether kidney stone history is associated with adverse 
      outcomes after percutaneous coronary intervention (PCI). Kidney stone formers 
      have an increased risk of developing coronary artery disease; however, whether 
      these patients have worse cardiac outcomes is unknown. MATERIALS AND METHODS: We 
      identified adult patients who underwent first-time PCI in Vanderbilt University 
      Medical Center (VUMC) Synthetic Derivative from 2008 to 2016 (n = 11,289) and in 
      a nationwide database of Taiwan (NHIRD) from 2005 to 2012 (n = 155,762). Odds 
      ratios (ORs) of 30-day in-hospital mortality and hazard ratios (HRs) of 1-year 
      and 3-year adverse outcomes associated with kidney stone history were estimated 
      using a propensity score approach. RESULTS: Overall, 294 and 12,286 stone formers 
      undergoing PCI were identified in the VUMC and NHIRD, respectively. After 
      matching, stone formers at VUMC were at higher risks of 30-day in-hospital 
      mortality (OR 2.79, 95% CI 1.15-6.69) and 1-year (HR 1.59, 95% CI 1.13-2.24) and 
      3-year (HR 1.36, 95% CI 1.02-1.81) myocardial infarction. In the NHIRD, kidney 
      stone history was associated with 1-year (HR 1.12, 95% CI 1.03-1.21) and 3-year 
      (HR 1.14, 95% CI 1.06-1.22) myocardial infarction. In a sensitivity analysis, 
      stone formers undergoing kidney stone surgery were marginally associated with 
      30-day in-hospital mortality (OR 1.21, 95% CI 0.99-1.48) and were associated with 
      3-year myocardial infarction (HR 1.13, 95% CI 1.02-1.25). CONCLUSION: Kidney 
      stone history is associated with poorer cardiac outcomes after PCI. Improving 
      secondary cardiac prevention strategies after PCI may be necessary for patients 
      with a history of kidney stone disease.
CI  - Copyright (c) 2019 Elsevier Inc. All rights reserved.
FAU - Lai, Chao-Han
AU  - Lai CH
AD  - Department of Surgery, National Cheng Kung University Hospital, College of 
      Medicine, National Cheng Kung University, Tainan, Taiwan; Department of 
      Biostatistics, Vanderbilt University Medical Center, Nashville, TN; Center for 
      Quantitative Sciences, Vanderbilt University Medical Center, Nashville, TN.
FAU - Huang, Li-Ching
AU  - Huang LC
AD  - Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN; 
      Center for Quantitative Sciences, Vanderbilt University Medical Center, 
      Nashville, TN.
FAU - Holby, S Neil
AU  - Holby SN
AD  - Department of Medicine, Vanderbilt University Medical Center, Nashville, TN.
FAU - Lai, Ying-Ju
AU  - Lai YJ
AD  - Department of Statistics, National Cheng Kung University, Tainan, Taiwan.
FAU - Su, Pei-Fang
AU  - Su PF
AD  - Department of Statistics, National Cheng Kung University, Tainan, Taiwan.
FAU - Cheng, Yu-Sheng
AU  - Cheng YS
AD  - Department of Urology, National Cheng Kung University Hospital, College of 
      Medicine, National Cheng Kung University, Tainan, Taiwan.
FAU - Shyr, Yu
AU  - Shyr Y
AD  - Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN; 
      Center for Quantitative Sciences, Vanderbilt University Medical Center, 
      Nashville, TN.
FAU - Hsi, Ryan S
AU  - Hsi RS
AD  - Department of Urology, Vanderbilt University Medical Center, Nashville, TN. 
      Electronic address: ryan.hsi@vanderbilt.edu.
LA  - eng
GR  - UL1 TR000445/TR/NCATS NIH HHS/United States
PT  - Journal Article
DEP - 20191104
PL  - United States
TA  - Urology
JT  - Urology
JID - 0366151
SB  - IM
MH  - Aged
MH  - Female
MH  - Humans
MH  - Kidney Calculi/*complications
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/*etiology
MH  - Percutaneous Coronary Intervention/*adverse effects
MH  - Postoperative Complications/*etiology
MH  - Retrospective Studies
PMC - PMC7008077
MID - NIHMS1542253
COIS- Conflict of Interest: None.
EDAT- 2019/11/08 06:00
MHDA- 2020/02/28 06:00
PMCR- 2021/02/01
CRDT- 2019/11/08 06:00
PHST- 2019/06/10 00:00 [received]
PHST- 2019/10/02 00:00 [revised]
PHST- 2019/10/15 00:00 [accepted]
PHST- 2019/11/08 06:00 [pubmed]
PHST- 2020/02/28 06:00 [medline]
PHST- 2019/11/08 06:00 [entrez]
PHST- 2021/02/01 00:00 [pmc-release]
AID - S0090-4295(19)30929-X [pii]
AID - 10.1016/j.urology.2019.10.009 [doi]
PST - ppublish
SO  - Urology. 2020 Feb;136:75-81. doi: 10.1016/j.urology.2019.10.009. Epub 2019 Nov 4.