PMID- 31698864
OWN - NLM
STAT- MEDLINE
DCOM- 20200327
LR  - 20200327
IS  - 1420-3049 (Electronic)
IS  - 1420-3049 (Linking)
VI  - 24
IP  - 22
DP  - 2019 Nov 6
TI  - Mercury Determination in Natural Zeolites by Thermal Decomposition Atomic 
      Absorption Spectrometry: Method Validation in Compliance with Requirements for 
      Use as Dietary Supplements.
LID - 10.3390/molecules24224023 [doi]
LID - 4023
AB  - Natural zeolites are hydrated aluminosilicate minerals that, due to their 
      remarkable physical-chemical properties of being molecular sieves and cation 
      exchangers, have applications in different areas such as environmental 
      protection, catalysis, animal feed, and dietary supplements. Since natural 
      zeolites may contain traces of undesirable compounds such as toxic metals, the 
      accurate quantification of these elements is necessary. In this study, a direct 
      method for Hg determination in zeolite samples based on the thermal desorption 
      atomic absorption spectrometry (TD-AAS) technique is fully validated, taking into 
      account the legislative requirements in the field. The chosen quantification 
      limit was 0.9 microg kg(-1), which is satisfactory for intended use. Trueness was 
      evaluated by recovery rate using certified reference materials containing 
      mercury, with satisfactory results. Other figures of merit, such as repeatability 
      and measurement uncertainty, also fulfill the legislative requirements related to 
      the analysis of dietary supplements. This paper presents, for the first time, a 
      fully validated method for mercury determination in zeolite samples, and the 
      obtained results reveal that the method can be applied successfully for the 
      intended purpose.
FAU - Senila, Marin
AU  - Senila M
AD  - National Institute for Research and Development of Optoelectronics Bucharest INOE 
      2000, Research Institute for Analytical Instrumentation, 67 Donath Street, 400293 
      Cluj-Napoca, Romania.
FAU - Cadar, Oana
AU  - Cadar O
AD  - National Institute for Research and Development of Optoelectronics Bucharest INOE 
      2000, Research Institute for Analytical Instrumentation, 67 Donath Street, 400293 
      Cluj-Napoca, Romania.
FAU - Senila, Lacrimioara
AU  - Senila L
AD  - National Institute for Research and Development of Optoelectronics Bucharest INOE 
      2000, Research Institute for Analytical Instrumentation, 67 Donath Street, 400293 
      Cluj-Napoca, Romania.
FAU - Hoaghia, Alexandra
AU  - Hoaghia A
AD  - National Institute for Research and Development of Optoelectronics Bucharest INOE 
      2000, Research Institute for Analytical Instrumentation, 67 Donath Street, 400293 
      Cluj-Napoca, Romania.
FAU - Miu, Ion
AU  - Miu I
AD  - SC UTCHIM SRL, 12 Buda Street, 240127 Ramnicu Valcea, Romania.
LA  - eng
GR  - MY SMIS 105654/Competitiveness Operational Programme of the Ministry of European 
      Funds Romania/
PT  - Journal Article
DEP - 20191106
PL  - Switzerland
TA  - Molecules
JT  - Molecules (Basel, Switzerland)
JID - 100964009
RN  - 1318-02-1 (Zeolites)
RN  - FXS1BY2PGL (Mercury)
SB  - IM
MH  - Dietary Supplements/*analysis
MH  - Food Contamination/analysis
MH  - Mercury/*analysis
MH  - Reproducibility of Results
MH  - Sensitivity and Specificity
MH  - *Spectrophotometry, Atomic/methods
MH  - X-Ray Diffraction
MH  - Zeolites/*analysis
PMC - PMC6891468
OTO - NOTNLM
OT  - TD-AAS
OT  - dietary supplements
OT  - green methods
OT  - mercury
OT  - method validation
OT  - zeolites
COIS- The authors declare no conflict of interest. The funders had no role in the 
      design of the study; in the collection, analyses, or interpretation of data; in 
      the writing of the manuscript, or in the decision to publish the results.
EDAT- 2019/11/09 06:00
MHDA- 2020/03/28 06:00
PMCR- 2019/11/06
CRDT- 2019/11/09 06:00
PHST- 2019/10/11 00:00 [received]
PHST- 2019/11/05 00:00 [revised]
PHST- 2019/11/06 00:00 [accepted]
PHST- 2019/11/09 06:00 [entrez]
PHST- 2019/11/09 06:00 [pubmed]
PHST- 2020/03/28 06:00 [medline]
PHST- 2019/11/06 00:00 [pmc-release]
AID - molecules24224023 [pii]
AID - molecules-24-04023 [pii]
AID - 10.3390/molecules24224023 [doi]
PST - epublish
SO  - Molecules. 2019 Nov 6;24(22):4023. doi: 10.3390/molecules24224023.