PMID- 31711636
OWN - NLM
STAT- MEDLINE
DCOM- 20200416
LR  - 20200416
IS  - 1879-1913 (Electronic)
IS  - 0002-9149 (Linking)
VI  - 125
IP  - 1
DP  - 2020 Jan 1
TI  - Usefulness of Cardiac Magnetic Resonance for Recurrent Pericarditis.
PG  - 146-151
LID - S0002-9149(19)31094-X [pii]
LID - 10.1016/j.amjcard.2019.09.026 [doi]
AB  - Cardiac magnetic resonance (CMR) offers the capability to objectively detect 
      pericarditis by identifying pericardial thickening, edema/inflammation by 
      Short-TI Inversion Recovery-T2 weighted (STIR-T2w) imaging, edema/inflammation or 
      fibrosis by late gadolinium enhancement (LGE), and presence of pericardial 
      effusion. This is especially helpful for the diagnosis of recurrent pericarditis. 
      Aim of the present paper is to assess the diagnostic accuracy of CMR findings as 
      well as their potential prognostic value for the diagnosis of recurrent 
      pericarditis. Multicenter cohort study of consecutive patients with recurrent 
      pericarditis evaluated by CMR. We included 128 consecutive cases (60 males, 47%; 
      mean age 48 +/- 14 years). CMR was performed at a mean time of 12 days (95% 
      confidence interval 15 to 21) after the clinical diagnosis. We evaluated the 
      diagnostic accuracy and areas under the receiver operating characteristic (ROC) 
      curve for CMR diagnostic criteria and complications (additional recurrences, 
      cardiac tamponade, and constrictive pericarditis). Areas under the ROC curve were 
      respectively 64% for pericardial thickening, 84% for pericardial edema, 82% for 
      pericardial LGE, and 71% for pericardial effusion. After a mean follow-up of 34 
      months, recurrences occurred in 52% of patients, tamponade in 6%, and 
      constrictive pericarditis in 11%. Using a multivariable Cox model, elevation of 
      CRP and presence of CMR pericardial thickening were predictors of adverse events, 
      whereas the presence of CMR LGE was associated with a lower risk. The prognostic 
      model for adverse events using gender, age, CRP level, and all CMR variables 
      showed a C-index of 0.84. In conclusion, CMR findings show high diagnostic 
      accuracy and may help identifying patients at higher risk of complications.
CI  - Copyright (c) 2019 Elsevier Inc. All rights reserved.
FAU - Imazio, Massimo
AU  - Imazio M
AD  - University Cardiology, Cardiovascular and Thoracic Department, AOU Citta della 
      Salute e della Scienza di Torino, Torino, Italy,. Electronic address: 
      massimo_imazio@yahoo.it.
FAU - Pivetta, Emanuele
AU  - Pivetta E
AD  - Cancer Epidemiology Unit, Emergency Medicine Division and High Dependency Unit, 
      Department of Medical Sciences, AOU Citta della Salute e della Scienza di Torino, 
      Torino, Italy.
FAU - Palacio Restrepo, Sara
AU  - Palacio Restrepo S
AD  - University Cardiology, Cardiovascular and Thoracic Department, AOU Citta della 
      Salute e della Scienza di Torino, Torino, Italy.
FAU - Sormani, Paola
AU  - Sormani P
AD  - Department of Cardiology and Cardiac Surgery, ASST Grande Ospedale Metropolitano 
      Niguarda, Milano, Italy.
FAU - Pedrotti, Patrizia
AU  - Pedrotti P
AD  - Department of Cardiology and Cardiac Surgery, ASST Grande Ospedale Metropolitano 
      Niguarda, Milano, Italy.
FAU - Quarta, Giovanni
AU  - Quarta G
AD  - Cardiology, Ospedale Papa Giovanni XXIII, Bergamo, Italy.
FAU - Brucato, Antonio
AU  - Brucato A
AD  - Department of Biomedical and Clinical Sciences "Sacco", Fatebenefratelli 
      Hospital, University of Milano, Italy.
FAU - Bubbico, Elisa
AU  - Bubbico E
AD  - University Cardiology, Cardiovascular and Thoracic Department, AOU Citta della 
      Salute e della Scienza di Torino, Torino, Italy.
FAU - Dal Corso, Maria
AU  - Dal Corso M
AD  - USC Radiologia Diagnostica, ASST Papa Giovanni Bergamo, Bergamo, Italy.
FAU - Milazzo, Angela
AU  - Milazzo A
AD  - Department of Cardiology and Cardiac Surgery, ASST Grande Ospedale Metropolitano 
      Niguarda, Milano, Italy.
FAU - Quattrocchi, Giuseppina
AU  - Quattrocchi G
AD  - Department of Cardiology and Cardiac Surgery, ASST Grande Ospedale Metropolitano 
      Niguarda, Milano, Italy.
FAU - Andriani, Monica
AU  - Andriani M
AD  - University Cardiology, Cardiovascular and Thoracic Department, AOU Citta della 
      Salute e della Scienza di Torino, Torino, Italy.
FAU - Lobetti Bodoni, Luisa
AU  - Lobetti Bodoni L
AD  - Radiology Department, AOU Citta della Salute e della Scienza di Torino, Torino, 
      Italy.
FAU - Davini, Ottavio
AU  - Davini O
AD  - Radiology Department, AOU Citta della Salute e della Scienza di Torino, Torino, 
      Italy.
FAU - Sironi, Sandro
AU  - Sironi S
AD  - Department of Biomedical and Clinical Sciences "Sacco", University of Milano, 
      Italy.
FAU - Giannattasio, Cristina
AU  - Giannattasio C
AD  - Department of Cardiology and Cardiac Surgery, ASST Grande Ospedale Metropolitano 
      Niguarda, Milano, Italy; School of Medicine and Surgery, Bicocca University, 
      Milano, Italy.
FAU - Giustetto, Carla
AU  - Giustetto C
AD  - University Cardiology, Cardiovascular and Thoracic Department, AOU Citta della 
      Salute e della Scienza di Torino, Torino, Italy,; Department of Medical Science, 
      University of Torino, Torino, Italy.
FAU - Bogaert, Jan
AU  - Bogaert J
AD  - Department of Imaging and Pathology, KU Leuven-University of Leuven, Leuven, 
      Belgium.
FAU - Adler, Yehuda
AU  - Adler Y
AD  - Sackler University, Tel Aviv, Israel.
FAU - Bucciarelli Ducci, Chiara
AU  - Bucciarelli Ducci C
AD  - Bristol NIHR Cardiovascular Biomedical Research Centre Bristol Heart Institute, 
      University of Bristol, Bristol, United Kingdom.
FAU - De Ferrari, Gaetano Maria
AU  - De Ferrari GM
AD  - University Cardiology, Cardiovascular and Thoracic Department, AOU Citta della 
      Salute e della Scienza di Torino, Torino, Italy,; Department of Medical Science, 
      University of Torino, Torino, Italy.
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PT  - Observational Study
PT  - Research Support, Non-U.S. Gov't
DEP - 20191011
PL  - United States
TA  - Am J Cardiol
JT  - The American journal of cardiology
JID - 0207277
SB  - IM
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Magnetic Resonance Imaging, Cine/*methods
MH  - Male
MH  - Middle Aged
MH  - Pericarditis/*diagnosis
MH  - Pericardium/*pathology
MH  - Predictive Value of Tests
MH  - ROC Curve
MH  - Recurrence
MH  - Retrospective Studies
MH  - Severity of Illness Index
EDAT- 2019/11/13 06:00
MHDA- 2020/04/17 06:00
CRDT- 2019/11/13 06:00
PHST- 2019/08/22 00:00 [received]
PHST- 2019/09/19 00:00 [revised]
PHST- 2019/09/20 00:00 [accepted]
PHST- 2019/11/13 06:00 [pubmed]
PHST- 2020/04/17 06:00 [medline]
PHST- 2019/11/13 06:00 [entrez]
AID - S0002-9149(19)31094-X [pii]
AID - 10.1016/j.amjcard.2019.09.026 [doi]
PST - ppublish
SO  - Am J Cardiol. 2020 Jan 1;125(1):146-151. doi: 10.1016/j.amjcard.2019.09.026. Epub 
      2019 Oct 11.