PMID- 31723708 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200929 IS - 2405-5794 (Electronic) IS - 2405-5794 (Linking) VI - 8 DP - 2017 Aug TI - Fifteen-year clinical experience with Mycobacterium haemophilum at the Mayo Clinic: A case series. PG - 26-32 LID - 10.1016/j.jctube.2017.06.002 [doi] AB - Mycobacterium haemophilum is an uncommonly encountered acid-fast staining bacillus (AFB) that can cause a broad range of infections. We describe a tertiary care center's experience with M. haemophilum infections identified from 2000 to 2015. Ten adult patients were identified with M. haemophilum infections, and most had immunocompromising conditions. M. haemophilum presented in one of two syndromes: a peripheral cutaneous infection presenting with skin nodularity and local invasion, and a cervicofacial infection involving regional lymph nodes. Duration of therapy was variable (0-18 months) and was dependent on the underlying syndrome and immunological status of the patient. Treatment responses were favorable in all patients. During therapy, three patients developed culture-negative aseptic cutaneous lesions, consistent with immunologic reconstitution inflammatory syndrome (IRIS); we postulate that such reactions may not be uncommon with select M. haemophilum infections. CI - (c) 2017 The Authors. FAU - Tyner, Harmony L AU - Tyner HL AD - St. Luke's Infectious Disease Associates, 920 First St., Duluth, MN 55805, United States. FAU - Wilson, John W AU - Wilson JW AD - Division of Infectious Diseases, Mayo Clinic, 200 First St., Rochester, MN 55905, United States. LA - eng PT - Journal Article PT - Review DEP - 20170628 PL - England TA - J Clin Tuberc Other Mycobact Dis JT - Journal of clinical tuberculosis and other mycobacterial diseases JID - 101682877 PMC - PMC6850245 OTO - NOTNLM OT - Acid fast bacilli OT - Case series OT - Mycobacterium haemophilum EDAT- 2017/06/28 00:00 MHDA- 2017/06/28 00:01 PMCR- 2017/06/28 CRDT- 2019/11/15 06:00 PHST- 2016/12/20 00:00 [received] PHST- 2017/06/12 00:00 [revised] PHST- 2017/06/17 00:00 [accepted] PHST- 2019/11/15 06:00 [entrez] PHST- 2017/06/28 00:00 [pubmed] PHST- 2017/06/28 00:01 [medline] PHST- 2017/06/28 00:00 [pmc-release] AID - S2405-5794(16)30057-2 [pii] AID - 10.1016/j.jctube.2017.06.002 [doi] PST - epublish SO - J Clin Tuberc Other Mycobact Dis. 2017 Jun 28;8:26-32. doi: 10.1016/j.jctube.2017.06.002. eCollection 2017 Aug.