PMID- 31725374
OWN - NLM
STAT- MEDLINE
DCOM- 20210624
LR  - 20240328
IS  - 1558-254X (Electronic)
IS  - 0278-0062 (Print)
IS  - 0278-0062 (Linking)
VI  - 39
IP  - 5
DP  - 2020 May
TI  - A Spatial Coherence Beamformer Design for Power Doppler Imaging.
PG  - 1558-1570
LID - 10.1109/TMI.2019.2953657 [doi]
AB  - Acoustic clutter is a primary source of image degradation in ultrasound imaging. 
      In the context of flow imaging, tissue and acoustic clutter signals are often 
      much larger in magnitude than the blood signal, which limits the sensitivity of 
      conventional power Doppler in SNR-limited environments. This has motivated the 
      development of coherence-based beamformers, including Coherent Flow Power Doppler 
      (CFPD), which have demonstrated efficacy in mitigating sources of diffuse 
      clutter. However, CFPD uses a measure of normalized coherence, which incurs a 
      non-linear relationship between image intensity and the magnitude of the blood 
      echo. As a result, CFPD is not a robust approach to study gradation of blood 
      signal energy, which depicts the fractional moving blood volume. We propose the 
      application of mutual intensity, rather than normalized coherence, to retain the 
      clutter suppression capability inherent in coherence beamforming, while 
      preserving the underlying signal energy. Feasibility of this approach was shown 
      via Field II simulations, phantoms, and in vivo human liver data. In addition, we 
      derive an adaptive statistical threshold for the suppression of residual noise 
      signals. Overall, this beamformer design shows promise as an alternative 
      technique to depict flow volume gradation in cluttered imaging environments.
FAU - Ozgun, Kathryn
AU  - Ozgun K
FAU - Tierney, Jaime
AU  - Tierney J
FAU - Byram, Brett
AU  - Byram B
LA  - eng
GR  - T32 EB021937/EB/NIBIB NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20191114
PL  - United States
TA  - IEEE Trans Med Imaging
JT  - IEEE transactions on medical imaging
JID - 8310780
SB  - IM
MH  - Humans
MH  - *Noise
MH  - Phantoms, Imaging
MH  - Signal Processing, Computer-Assisted
MH  - Signal-To-Noise Ratio
MH  - Ultrasonography
MH  - *Ultrasonography, Doppler
PMC - PMC7265983
MID - NIHMS1590729
EDAT- 2019/11/15 06:00
MHDA- 2021/06/25 06:00
PMCR- 2021/05/01
CRDT- 2019/11/15 06:00
PHST- 2019/11/15 06:00 [pubmed]
PHST- 2021/06/25 06:00 [medline]
PHST- 2019/11/15 06:00 [entrez]
PHST- 2021/05/01 00:00 [pmc-release]
AID - 10.1109/TMI.2019.2953657 [doi]
PST - ppublish
SO  - IEEE Trans Med Imaging. 2020 May;39(5):1558-1570. doi: 10.1109/TMI.2019.2953657. 
      Epub 2019 Nov 14.