PMID- 31728654
OWN - NLM
STAT- MEDLINE
DCOM- 20200511
LR  - 20240328
IS  - 1539-0829 (Electronic)
IS  - 1534-4827 (Print)
IS  - 1534-4827 (Linking)
VI  - 19
IP  - 11
DP  - 2019 Nov 14
TI  - The Role of Bariatric Surgery on Diabetes and Diabetic Care Compliance.
PG  - 125
LID - 10.1007/s11892-019-1236-0 [doi]
AB  - PURPOSE OF REVIEW: Bariatric surgery is a durable and long-term solution to treat 
      both obesity and its associated comorbidities, specifically type 2 diabetes 
      mellitus (T2DM). Many studies have demonstrated the benefits of bariatric surgery 
      on T2DM, but weight recidivism along with recurrence of comorbidities can be seen 
      following these procedures. Patient compliance post-bariatric surgery is linked 
      to weight loss outcomes and comorbidity improvement/resolution. The role of 
      compliance with respect to T2DM medication in bariatric patients specifically has 
      not recently been examined. This article seeks to review the role of bariatric 
      surgery on short- and long-term resolution of T2DM, recurrence, and compliance 
      with T2DM medication following bariatric surgery. RECENT FINDINGS: Seven 
      randomized control trials have examined metabolic surgery versus medical therapy 
      in glycemic control in patients meeting criteria for severe obesity. Six out of 
      seven studies demonstrate a significant advantage in the surgical arms with 
      regards to glycemic control, as well as secondary endpoints such as weight loss, 
      serum lipid levels, blood pressure, renal function, and other parameters. While 
      patient compliance with lifestyle modifications post-bariatric surgery is linked 
      to weight loss outcomes, there are no studies to date that directly evaluate the 
      role of lifestyle modifications and T2DM medication adherence in the management 
      of T2DM post-bariatric surgery. Bariatric surgery is an effective treatment 
      option to achieve long-term weight loss and resolution of obesity-related medical 
      comorbidities, specifically T2DM. Patient compliance to lifestyle modifications 
      post-bariatric surgery is linked to weight loss outcomes and comorbidity 
      resolution. The role of diabetic care compliance in bariatric patient outcomes, 
      however, is poorly understood. Further studies are needed to elucidate the 
      predictors and associated risk factors for non-compliance in this patient 
      population.
FAU - Jackson, Hope T
AU  - Jackson HT
AD  - Department of Surgery, School of Medicine and Health Sciences, The George 
      Washington University, Washington, DC, USA. hjackson@mfa.gwu.edu.
FAU - Anekwe, Chika
AU  - Anekwe C
AD  - Harvard Medical School, Boston, MA, USA.
AD  - Internal Medicine-Endocrine Unit, Massachusetts General Hospital, Boston, MA, 
      USA.
AD  - Massachusetts General Hospital (MGH) Weight Center, Boston, MA, USA.
FAU - Chang, Julietta
AU  - Chang J
AD  - Weight Loss Surgical Institute of Central Coast, Marian Regional Medical Center, 
      Santa Monica, CA, USA.
FAU - Haskins, Ivy N
AU  - Haskins IN
AD  - Department of Surgery, School of Medicine and Health Sciences, The George 
      Washington University, Washington, DC, USA.
FAU - Stanford, Fatima Cody
AU  - Stanford FC
AD  - Harvard Medical School, Boston, MA, USA.
AD  - Massachusetts General Hospital (MGH) Weight Center, Boston, MA, USA.
AD  - Internal Medicine-Neuroendocrine Unit and Pediatrics Endocrinology, Massachusetts 
      General Hospital, Boston, MA, USA.
LA  - eng
GR  - L30 DK118710/DK/NIDDK NIH HHS/United States
GR  - P30 DK040561/DK/NIDDK NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Review
DEP - 20191114
PL  - United States
TA  - Curr Diab Rep
JT  - Current diabetes reports
JID - 101093791
SB  - IM
MH  - *Bariatric Surgery
MH  - Diabetes Mellitus, Type 2/complications/*therapy
MH  - Humans
MH  - *Obesity, Morbid/complications/surgery
MH  - Patient Compliance
MH  - Weight Loss
PMC - PMC7205514
MID - NIHMS1583438
OTO - NOTNLM
OT  - Diabetes
OT  - Metabolic and bariatric surgery
OT  - Patient compliance
COIS- Conflict of Interest Hope T. Jackson, Chika Anekwe, Julietta Chang, and Ivy N. 
      Haskins declare that they have no conflict of interest. Fatima Cody Stanford 
      serves on the advisory board of Novo Nordisk.
EDAT- 2019/11/16 06:00
MHDA- 2020/05/12 06:00
PMCR- 2020/11/14
CRDT- 2019/11/16 06:00
PHST- 2019/11/16 06:00 [entrez]
PHST- 2019/11/16 06:00 [pubmed]
PHST- 2020/05/12 06:00 [medline]
PHST- 2020/11/14 00:00 [pmc-release]
AID - 10.1007/s11892-019-1236-0 [pii]
AID - 10.1007/s11892-019-1236-0 [doi]
PST - epublish
SO  - Curr Diab Rep. 2019 Nov 14;19(11):125. doi: 10.1007/s11892-019-1236-0.