PMID- 31735797 OWN - NLM STAT- MEDLINE DCOM- 20200914 LR - 20200914 IS - 1349-7235 (Electronic) IS - 0918-2918 (Print) IS - 0918-2918 (Linking) VI - 59 IP - 5 DP - 2020 Mar 1 TI - Metachronous Pancreatic Ductal Adenocarcinoma with Adjacent Serous Cystadenoma that Was Preoperatively Diagnosed by EUS-FNA: A Case Report and Review of the Literature. PG - 649-656 LID - 10.2169/internalmedicine.3912-19 [doi] AB - Pancreatic serous cystic neoplasms (SCNs), such as serous cystadenoma (SCA), are generally recognized as benign because malignant counterparts of SCNs have been extremely rare. In clinical practice, pancreatic cystic neoplasms diagnosed as SCNs have been managed by conservative observation, as long as the patients remained asymptomatic. We herein report a case of metachronous ductal adenocarcinoma that was discovered during long-term follow-up of SCN and review the related literature. To our knowledge, this was the first reported case of the local presence of ductal adenocarcinoma adjacent to SCA that was preoperatively diagnosed by endoscopic ultrasound-guided fine-needle aspiration. FAU - Yoshida, Michihiro AU - Yoshida M AD - Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Japan. FAU - Naitoh, Itaru AU - Naitoh I AD - Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Japan. FAU - Hayashi, Kazuki AU - Hayashi K AD - Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Japan. FAU - Jinno, Naruomi AU - Jinno N AD - Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Japan. FAU - Natsume, Makoto AU - Natsume M AD - Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Japan. FAU - Hori, Yasuki AU - Hori Y AD - Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Japan. FAU - Kato, Akihisa AU - Kato A AD - Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Japan. FAU - Kachi, Kenta AU - Kachi K AD - Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Japan. FAU - Asano, Go AU - Asano G AD - Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Japan. FAU - Matsuo, Yoichi AU - Matsuo Y AD - Department of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences, Japan. FAU - Takahashi, Satoru AU - Takahashi S AD - Department of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, Japan. FAU - Kataoka, Hiromi AU - Kataoka H AD - Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Japan. LA - eng PT - Case Reports PT - Journal Article DEP - 20191118 PL - Japan TA - Intern Med JT - Internal medicine (Tokyo, Japan) JID - 9204241 SB - IM MH - Aged MH - Carcinoma, Pancreatic Ductal/diagnostic imaging/*pathology MH - Cystadenoma, Serous/diagnostic imaging/*pathology MH - Endoscopic Ultrasound-Guided Fine Needle Aspiration MH - Humans MH - Male MH - Pancreatic Neoplasms/diagnostic imaging/*pathology PMC - PMC7086322 OTO - NOTNLM OT - diffusion-weighted magnetic resonance image (DWI) OT - endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) OT - pancreatic ductal adenocarcinoma (PDAC) OT - serous cystadenoma (SCA) OT - serous cystic neoplasm (SCN) COIS- The authors state that they have no Conflict of Interest (COI). EDAT- 2019/11/19 06:00 MHDA- 2020/09/15 06:00 PMCR- 2020/03/01 CRDT- 2019/11/19 06:00 PHST- 2019/11/19 06:00 [pubmed] PHST- 2020/09/15 06:00 [medline] PHST- 2019/11/19 06:00 [entrez] PHST- 2020/03/01 00:00 [pmc-release] AID - 10.2169/internalmedicine.3912-19 [doi] PST - ppublish SO - Intern Med. 2020 Mar 1;59(5):649-656. doi: 10.2169/internalmedicine.3912-19. Epub 2019 Nov 18.