PMID- 31735991 OWN - NLM STAT- MEDLINE DCOM- 20200214 LR - 20200214 IS - 1432-1211 (Electronic) IS - 0093-7711 (Linking) VI - 72 IP - 1-2 DP - 2020 Feb TI - Update 2020: nomenclature and listing of celiac disease-relevant gluten epitopes recognized by CD4(+) T cells. PG - 85-88 LID - 10.1007/s00251-019-01141-w [doi] AB - Celiac disease is caused by an abnormal intestinal T cell response to cereal gluten proteins. The disease has a strong human leukocyte antigen (HLA) association, and CD4(+) T cells recognizing gluten epitopes presented by disease-associated HLA-DQ allotypes are considered to be drivers of the disease. This paper provides an update of the currently known HLA-DQ restricted gluten T cell epitopes with their names and sequences. FAU - Sollid, Ludvig M AU - Sollid LM AD - KG Jebsen Coeliac Disease Research Centre and Department of Immunology, Oslo University Hospital, Rikshospitalet, University of Oslo, Oslo, Norway. l.m.sollid@medisin.uio.no. FAU - Tye-Din, Jason A AU - Tye-Din JA AD - Immunology Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia. FAU - Qiao, Shuo-Wang AU - Qiao SW AD - KG Jebsen Coeliac Disease Research Centre and Department of Immunology, Oslo University Hospital, Rikshospitalet, University of Oslo, Oslo, Norway. FAU - Anderson, Robert P AU - Anderson RP AD - Immunology Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia. FAU - Gianfrani, Carmen AU - Gianfrani C AD - Institute of Biochemistry and Cell Biology, National Research Council of Italy, Naples, Italy. FAU - Koning, Frits AU - Koning F AD - Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands. LA - eng PT - Journal Article PT - Review DEP - 20191118 PL - United States TA - Immunogenetics JT - Immunogenetics JID - 0420404 RN - 0 (Epitopes, T-Lymphocyte) RN - 8002-80-0 (Glutens) SB - IM MH - Animals MH - CD4-Positive T-Lymphocytes/*immunology MH - Celiac Disease/*immunology MH - Epitopes, T-Lymphocyte/*immunology MH - Glutens/*immunology MH - Humans MH - Major Histocompatibility Complex/*immunology MH - Terminology as Topic OTO - NOTNLM OT - Celiac disease OT - Epitopes OT - Gluten OT - HLA-DQ2 OT - HLA-DQ8 OT - T cell EDAT- 2019/11/19 06:00 MHDA- 2020/02/15 06:00 CRDT- 2019/11/19 06:00 PHST- 2019/10/16 00:00 [received] PHST- 2019/10/16 00:00 [accepted] PHST- 2019/11/19 06:00 [pubmed] PHST- 2020/02/15 06:00 [medline] PHST- 2019/11/19 06:00 [entrez] AID - 10.1007/s00251-019-01141-w [pii] AID - 10.1007/s00251-019-01141-w [doi] PST - ppublish SO - Immunogenetics. 2020 Feb;72(1-2):85-88. doi: 10.1007/s00251-019-01141-w. Epub 2019 Nov 18.