PMID- 31739696 OWN - NLM STAT- MEDLINE DCOM- 20200109 LR - 20200109 IS - 1744-764X (Electronic) IS - 1474-0338 (Linking) VI - 19 IP - 1 DP - 2020 Jan TI - 18(th) Annual Meeting of the Safety Pharmacology Society: drug safety assessment on gastrointestinal system functions. PG - 19-22 LID - 10.1080/14740338.2020.1694902 [doi] AB - Introduction: The 18(th) Annual Meeting of the Safety Pharmacology Society included a session dedicated to the assessment of drug safety on the gastrointestinal (GI) system.Areas covered: GI anatomy, physiology, adverse effects (AEs) of chemical and biological therapies, and approaches to mitigate them.Expert opinion: GI AEs, albeit common and generally of minor intensity, may prolong clinical development time and reduce patient compliance. FAU - Cavero, Icilio AU - Cavero I AD - Independent Consultant in Safety Pharmacology, Paris, France. FAU - Holzgrefe, Henry H AU - Holzgrefe HH AUID- ORCID: 0000-0002-8165-0755 AD - Independent Consultant in Safety Pharmacology, Reno, NV, USA. LA - eng PT - Journal Article DEP - 20191208 PL - England TA - Expert Opin Drug Saf JT - Expert opinion on drug safety JID - 101163027 SB - IM MH - Animals MH - Drug Development/methods MH - Drug-Related Side Effects and Adverse Reactions/*epidemiology MH - Gastrointestinal Diseases/*chemically induced MH - Gastrointestinal Tract/*drug effects MH - Humans OTO - NOTNLM OT - Adverse drug reactions OT - ICH S7A guidelines OT - adverse effect mitigation OT - anticancer agents OT - drug safety OT - gastrointestinal system OT - safety pharmacology EDAT- 2019/11/20 06:00 MHDA- 2020/01/10 06:00 CRDT- 2019/11/20 06:00 PHST- 2019/11/20 06:00 [pubmed] PHST- 2020/01/10 06:00 [medline] PHST- 2019/11/20 06:00 [entrez] AID - 10.1080/14740338.2020.1694902 [doi] PST - ppublish SO - Expert Opin Drug Saf. 2020 Jan;19(1):19-22. doi: 10.1080/14740338.2020.1694902. Epub 2019 Dec 8.