PMID- 31740627
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200928
IS  - 2411-5150 (Electronic)
IS  - 2411-5150 (Linking)
VI  - 1
IP  - 1
DP  - 2016 Apr 12
TI  - Comparing Macular Thickness Measurements in Patients with Diabetic Macular Edema 
      with the Optos Spectral OCT/SLO and Heidelberg Spectralis HRA + OCT.
LID - 10.3390/vision1010002 [doi]
LID - 2
AB  - The aim of this study was to compare measurements of macular thickness, obtained 
      from patients with diabetic macular edema, using two spectral-domain optical 
      coherence tomography (SD-OCT) devices. These were the Spectralis Heidelberg 
      Retina Angiograph + Optical Coherence Tomography (HRA + OCT) (Heidelberg 
      Engineering), which is often considered the gold-standard for OCT measurement, 
      and the Spectral Optical Coherence Tomography/Scanning Laser Ophthalmoscopy 
      (OCT/SLO) (Optos plc), which can additionally perform microperimetry, a useful 
      measure of visual function. In this prospective observational study, each eye had 
      SD-OCT performed with both devices on the same day by the same investigator. Mean 
      retinal thickness was calculated, and compared between the devices, for central 
      and parafoveal zones within 3 mm of the fovea. 62 eyes were included. In the 
      central, superior, temporal, inferior and nasal zones respectively, mean retinal 
      thickness with Spectralis HRA+OCT was (in microns) 310, 343, 344, 332 and 340; 
      measurements with Spectral OCT/SLO were 237, 298, 297, 289 and 290. Pearson 
      correlations between the devices were 0.752, 0.85, 0.928, 0.839, and 0.823 (p < 
      0.0001). Although absolute measurements between the devices were significantly 
      different and therefore not interchangeable, the correlation between the devices 
      was over 75% and statistically significant in all zones. Thus, the Spectral 
      OCT/SLO could reliably be used for SD-OCT in patients who may also require 
      microperimetry assessment.
FAU - Sachdev, Amun
AU  - Sachdev A
AD  - Oxford Eye Hospital, University of Oxford, Oxford, Oxfordshire, OX3 9DU, UK.
AD  - Sandwell & West Birmingham Hospitals NHS Trust, Dudley road, Birmingham, West 
      Midlands, B18 7QH, UK.
FAU - Edington, Magdalena
AU  - Edington M
AD  - Oxford Eye Hospital, University of Oxford, Oxford, Oxfordshire, OX3 9DU, UK.
AD  - NHS Greater Glasgow and Clyde, 1055 Great Western Road, Glasgow, G12 0YN, UK.
FAU - Morjaria, Rupal
AU  - Morjaria R
AUID- ORCID: 0000-0003-4751-6488
AD  - Oxford Eye Hospital, University of Oxford, Oxford, Oxfordshire, OX3 9DU, UK.
AD  - Sandwell & West Birmingham Hospitals NHS Trust, Dudley road, Birmingham, West 
      Midlands, B18 7QH, UK.
FAU - Chong, Ngaihang Victor
AU  - Chong NV
AD  - Oxford Eye Hospital, University of Oxford, Oxford, Oxfordshire, OX3 9DU, UK.
LA  - eng
PT  - Journal Article
DEP - 20160412
PL  - Switzerland
TA  - Vision (Basel)
JT  - Vision (Basel, Switzerland)
JID - 101733282
PMC - PMC6849021
OTO - NOTNLM
OT  - diabetic macular edema
OT  - heidelberg spectralis
OT  - optical coherence tomography
OT  - optos spectral OCT/SLO
OT  - retinal thickness
COIS- The authors declare no conflict of interest.
EDAT- 2016/04/12 00:00
MHDA- 2016/04/12 00:01
PMCR- 2016/04/12
CRDT- 2019/11/20 06:00
PHST- 2016/01/05 00:00 [received]
PHST- 2016/02/17 00:00 [revised]
PHST- 2016/03/03 00:00 [accepted]
PHST- 2019/11/20 06:00 [entrez]
PHST- 2016/04/12 00:00 [pubmed]
PHST- 2016/04/12 00:01 [medline]
PHST- 2016/04/12 00:00 [pmc-release]
AID - vision1010002 [pii]
AID - vision-01-00002 [pii]
AID - 10.3390/vision1010002 [doi]
PST - epublish
SO  - Vision (Basel). 2016 Apr 12;1(1):2. doi: 10.3390/vision1010002.