PMID- 31742693
OWN - NLM
STAT- MEDLINE
DCOM- 20200122
LR  - 20200122
IS  - 1097-0010 (Electronic)
IS  - 0022-5142 (Linking)
VI  - 100
IP  - 3
DP  - 2020 Feb
TI  - Dietary supplementation with pioglitazone hydrochloride and chromium methionine 
      manipulates lipid metabolism with related genes to improve the intramuscular fat 
      and fatty acid profile of yellow-feathered chickens.
PG  - 1311-1319
LID - 10.1002/jsfa.10146 [doi]
AB  - BACKGROUND: Intramuscular fat (IMF) and polyunsaturated fatty acids (PUFAs) have 
      been thought to play a crucial role in improving meat quality. Considering the 
      ability of pioglitazone hydrochloride (PGZ) to deposit fat, and the anti-stress 
      capability of chromium methionine (CrMet), we combined these compounds to produce 
      higher quality meat in poultry. A total of 3000 female chickens were divided into 
      four groups (five replicates, each with 150 chickens): control, control 
      plus15 mg.kg(-1) PGZ, control plus 200 mug.kg(-1) CrMet, and control 
      plus15 mg.kg(-1) PGZ plus 200 mug.kg(-1) CrMet. The experiment lasted for 28 days. 
      RESULTS: Compared to the control group and the PGZ group, the average daily gain 
      (ADG) was significantly increased in the PGZ plus CrMet group, whereas the 
      feed-to-gain ratio (F/G) was decreased from 0 to 14 days. Meanwhile, the redness 
      value of breast muscle and IMF of thigh muscle increased in the PGZ plus CrMet 
      group compared with the control group and these detections in the PGZ plus CrMet 
      group exhibited highest value among the four groups. The cooking loss decreased 
      in the breast muscle and thigh muscle after PGZ combined with CrMet in diets. The 
      percentages of C16:1, C18:2n-6 and PUFAs increased in the PGZ plus CrMet group. 
      The mRNA abundance of peroxisome proliferator activated receptor (PPAR) gamma, PPAR 
      coactivator 1 alpha, and fatty acid binding protein 3 was significantly enhanced with 
      PGZ plus CrMet supplementation. CONCLUSION: Collectively, dietary supplementation 
      with PGZ plus CrMet improved growth performance and meat quality by decreasing 
      the cooking loss and increasing the IMF and PUFA levels. (c) 2019 Society of 
      Chemical Industry.
CI  - (c) 2019 Society of Chemical Industry.
FAU - Jin, Cheng-Long
AU  - Jin CL
AUID- ORCID: 0000-0003-4475-4595
AD  - College of Animal Science, South China Agricultural University/Guangdong 
      Provincial Key Laboratory of Animal Nutrition Control/Key Laboratory of Chicken 
      Genetics, Breeding and Reproduction, Ministry of Agriculture Guangzhou, 
      Guangzhou, Guangdong, China.
FAU - Zeng, Huan-Ren
AU  - Zeng HR
AD  - College of Animal Science, South China Agricultural University/Guangdong 
      Provincial Key Laboratory of Animal Nutrition Control/Key Laboratory of Chicken 
      Genetics, Breeding and Reproduction, Ministry of Agriculture Guangzhou, 
      Guangzhou, Guangdong, China.
FAU - Gao, Chun-Qi
AU  - Gao CQ
AD  - College of Animal Science, South China Agricultural University/Guangdong 
      Provincial Key Laboratory of Animal Nutrition Control/Key Laboratory of Chicken 
      Genetics, Breeding and Reproduction, Ministry of Agriculture Guangzhou, 
      Guangzhou, Guangdong, China.
FAU - Yan, Hui-Chao
AU  - Yan HC
AD  - College of Animal Science, South China Agricultural University/Guangdong 
      Provincial Key Laboratory of Animal Nutrition Control/Key Laboratory of Chicken 
      Genetics, Breeding and Reproduction, Ministry of Agriculture Guangzhou, 
      Guangzhou, Guangdong, China.
FAU - Tan, Hui-Ze
AU  - Tan HZ
AD  - WENS Foodstuff Group Co., Ltd, Guangzhou, Guangdong, China.
FAU - Wang, Xiu-Qi
AU  - Wang XQ
AUID- ORCID: 0000-0003-2033-9485
AD  - College of Animal Science, South China Agricultural University/Guangdong 
      Provincial Key Laboratory of Animal Nutrition Control/Key Laboratory of Chicken 
      Genetics, Breeding and Reproduction, Ministry of Agriculture Guangzhou, 
      Guangzhou, Guangdong, China.
LA  - eng
GR  - 2018YFD0500403/the National Key R&D Program of China/
GR  - 2018B030315001/the Natural Science Foundation of Guangdong Province, China/
GR  - 201710010110/the Pearl River Technology Science and Technology Nova Projects of 
      Guangzhou, China/
GR  - 2016LM1116/the Technical System of Poultry Industry of Guangdong Province, China/
PT  - Journal Article
DEP - 20191205
PL  - England
TA  - J Sci Food Agric
JT  - Journal of the science of food and agriculture
JID - 0376334
RN  - 0 (Fatty Acids)
RN  - 0R0008Q3JB (Chromium)
RN  - AE28F7PNPL (Methionine)
RN  - X4OV71U42S (Pioglitazone)
SB  - IM
MH  - Animal Feed/analysis
MH  - Animal Nutritional Physiological Phenomena
MH  - Animals
MH  - Chickens/genetics/*metabolism
MH  - Chromium/administration & dosage/*metabolism
MH  - Cooking
MH  - Diet/veterinary
MH  - Dietary Supplements/*analysis
MH  - Fatty Acids/chemistry/*metabolism
MH  - Female
MH  - Lipid Metabolism
MH  - Meat/analysis
MH  - Methionine/administration & dosage/*metabolism
MH  - Muscle, Skeletal/chemistry/*metabolism
MH  - Pioglitazone/administration & dosage/*metabolism
OTO - NOTNLM
OT  - chromium methionine
OT  - growth performance
OT  - meat quality
OT  - pioglitazone hydrochloride
OT  - yellow-feathered chickens
EDAT- 2019/11/20 06:00
MHDA- 2020/01/23 06:00
CRDT- 2019/11/20 06:00
PHST- 2019/09/27 00:00 [received]
PHST- 2019/11/14 00:00 [revised]
PHST- 2019/11/14 00:00 [accepted]
PHST- 2019/11/20 06:00 [pubmed]
PHST- 2020/01/23 06:00 [medline]
PHST- 2019/11/20 06:00 [entrez]
AID - 10.1002/jsfa.10146 [doi]
PST - ppublish
SO  - J Sci Food Agric. 2020 Feb;100(3):1311-1319. doi: 10.1002/jsfa.10146. Epub 2019 
      Dec 5.