PMID- 31742942
OWN - NLM
STAT- MEDLINE
DCOM- 20191127
LR  - 20200108
IS  - 1660-9379 (Print)
IS  - 1660-9379 (Linking)
VI  - 15
IP  - 671
DP  - 2019 Nov 13
TI  - [Screening for latent tuberculosis infection in immunosuppressed patients not 
      infected with HIV].
PG  - 2105-2108
AB  - Screening for latent tuberculosis infection (LTI) is recommended in 
      immunosuppressed patients due to an increased risk of progression from LTI to 
      active tuberculosis. Screening involves indirect immunological tests such as the 
      tuberculin skin test (TST) and the interferon-y release assays (IGRAs). IGRAs 
      seem to show superior performance compared to TST in screening for LTI. However, 
      their use and interpretation in immunosuppressed patients is questionable, 
      particularly because of an increased number of false negative or indeterminate 
      results and a low agreement between tests. Presently, there are no swiss national 
      recommendations for their use in immunosuppressed -patients, except for 
      candidates to anti-TNF treatment.
FAU - Vongthilath, Rechana
AU  - Vongthilath R
AD  - Service de pneumologie, HUG, 1211 Geneve 14.
FAU - Gasche-Soccal, Paola
AU  - Gasche-Soccal P
AD  - Service de pneumologie, HUG, 1211 Geneve 14.
FAU - Roux-Lombard, Pascale
AU  - Roux-Lombard P
AD  - Service d'immunologie et d'allergologie, HUG, 1211 Geneve 14.
FAU - Janssens, Jean-Paul
AU  - Janssens JP
AD  - Service de pneumologie, HUG, 1211 Geneve 14.
LA  - fre
PT  - Journal Article
PT  - Review
TT  - Depistage de l'infection tuberculeuse latente chez les patients immuno-supprimes 
      non infectes par le VIH.
PL  - Switzerland
TA  - Rev Med Suisse
JT  - Revue medicale suisse
JID - 101219148
RN  - 0 (Tumor Necrosis Factor-alpha)
SB  - IM
MH  - Humans
MH  - *Immunocompromised Host
MH  - Immunologic Deficiency Syndromes/*complications/*microbiology
MH  - Interferon-gamma Release Tests
MH  - Latent Tuberculosis/*complications/*diagnosis
MH  - Sensitivity and Specificity
MH  - Tuberculin Test
MH  - Tumor Necrosis Factor-alpha/antagonists & inhibitors
COIS- Les auteurs n'ont declare aucun conflit d'interets en relation avec cet article.
EDAT- 2019/11/20 06:00
MHDA- 2019/11/28 06:00
CRDT- 2019/11/20 06:00
PHST- 2019/11/20 06:00 [entrez]
PHST- 2019/11/20 06:00 [pubmed]
PHST- 2019/11/28 06:00 [medline]
AID - RMS0671-007 [pii]
PST - ppublish
SO  - Rev Med Suisse. 2019 Nov 13;15(671):2105-2108.