PMID- 3174388
OWN - NLM
STAT- MEDLINE
DCOM- 19881107
LR  - 20190726
IS  - 0031-6768 (Print)
IS  - 0031-6768 (Linking)
VI  - 412
IP  - 1-2
DP  - 1988 Jul
TI  - Species-specific effects of chronic nerve stimulation upon tibialis anterior 
      muscle in mouse, rat, guinea pig, and rabbit.
PG  - 86-92
AB  - Tibialis anterior (TA) muscle of mouse, rat, guinea pig, and rabbit was 
      indirectly stimulated for 10 h/day at 10 Hz up to 28 days. Changes in the 
      activity levels of hexokinase (HK), phosphofructokinase (PFK), 
      glyceraldehydephosphate dehydrogenase (GAPDH), lactate dehydrogenase (LDH), 
      creatine kinase (CK), citrate synthase (CS), malate dehydrogenase (MDH), 
      3-hydroxyacyl-CoA dehydrogenase (HADH), and beta-hydroxybutyrate dehydrogenase 
      (HBDH) were compared. Although the direction of changes in the enzyme activity 
      pattern was in accordance with previous findings on rabbit TA, the magnitude of 
      the responses varied markedly between the mammals under study. Mouse TA was 
      almost unaffected. A major effect of chronic stimulation in rat, guinea pig and 
      rabbit was an increase in enzyme activities of aerobic-oxidative metabolism. 
      According to intrinsic differences of the muscles under study, the increases 
      varied among the species and appeared to be inversely related to the basal levels 
      of these enzymes in the unstimulated muscles. Conversely, glycolytic enzyme 
      activities (PFK, GAPDH, LDH) markedly decreased in rat, guinea pig, and rabbit, 
      and were only slightly reduced in mouse. Changes in HK and HBDH activities 
      displayed the largest variations in the induced change between species. These 
      results indicate species-specific patterns of metabolic adaptation to increased 
      contractile activity.
FAU - Simoneau, J A
AU  - Simoneau JA
AD  - Fakultat fur Biologie, Universitat Konstanz, Federal Republic of Germany.
FAU - Pette, D
AU  - Pette D
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Germany
TA  - Pflugers Arch
JT  - Pflugers Archiv : European journal of physiology
JID - 0154720
RN  - EC 1.1.1.27 (L-Lactate Dehydrogenase)
RN  - EC 2.7.3.2 (Creatine Kinase)
SB  - IM
MH  - Animals
MH  - Creatine Kinase/metabolism
MH  - Electric Stimulation
MH  - Female
MH  - Guinea Pigs
MH  - L-Lactate Dehydrogenase/metabolism
MH  - Male
MH  - Mice
MH  - Mice, Inbred Strains
MH  - Muscle Contraction
MH  - Muscles/enzymology/*innervation/physiology
MH  - Rabbits
MH  - Rats
MH  - Rats, Inbred Strains
MH  - *Species Specificity
MH  - Tibia/*analysis
EDAT- 1988/07/01 00:00
MHDA- 1988/07/01 00:01
CRDT- 1988/07/01 00:00
PHST- 1988/07/01 00:00 [pubmed]
PHST- 1988/07/01 00:01 [medline]
PHST- 1988/07/01 00:00 [entrez]
AID - 10.1007/BF00583735 [doi]
PST - ppublish
SO  - Pflugers Arch. 1988 Jul;412(1-2):86-92. doi: 10.1007/BF00583735.