PMID- 31744654 OWN - NLM STAT- MEDLINE DCOM- 20200821 LR - 20200821 IS - 1532-8171 (Electronic) IS - 0735-6757 (Linking) VI - 38 IP - 8 DP - 2020 Aug TI - How much change in pain score does really matter to patients? PG - 1641-1646 LID - S0735-6757(19)30638-2 [pii] LID - 10.1016/j.ajem.2019.158489 [doi] AB - OBJECTIVE: The goal of this study was to determine the minimal change in pain score recognized by patients as meaningful known as minimal clinically important difference (MCID). METHODS: Pain was recordedupon admission, 30 and 60 min later and patients were asked todescribe the extent of pain change on a 5-point Likert scale ranging from "much better" to "much worse". Patients reported their pain by two common pain scales comprising numeric rating scale (NRS) and visual analog scale (VAS). We used receiver operating characteristiccurve to assess the accuracy of pain scales. We then calculated the mean change in pain scores among patients who reported their pain change as "a little better" or "a little worse" and also analyzed regression to evaluate the MCID. RESULTS: A total of 150 patients and 253 pain changes were recruited. The MCID +/- SD (95% CI) was 1.65 +/- 1.58 (1.32-1.97) for NRS and 16.55 +/- 17.53 (12.96-20.15) for VAS. The area under the curve by NRS and VAS were 0.86 and 0.89. For linear regression, the line slope and the y-intercept were 17.56 and 1.88, for VAS; these values were 1.73 and 0.31 for NRS, respectively. CONCLUSIONS: Recognizing the extent of change in pain score that really matters to patients is crucial for the evaluation of treatment effect. Patients perceived a change of 1.65 points on NRS and 16.55 on VAS in their pain severity as meaningful. This value was not different whether the pain was perceived alleviated or aggravated. CI - Copyright (c) 2019 Elsevier Inc. All rights reserved. FAU - Bahreini, Maryam AU - Bahreini M AD - Department of Emergency Medicine, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran. FAU - Safaie, Arash AU - Safaie A AD - Department of Emergency Medicine, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran. FAU - Mirfazaelian, Hadi AU - Mirfazaelian H AD - Department of Emergency Medicine, Tehran University of Medical Sciences, Tehran, Iran. FAU - Jalili, Mohammad AU - Jalili M AD - Department of Emergency Medicine, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: mjalili@tums.ac.ir. LA - eng PT - Journal Article DEP - 20191104 PL - United States TA - Am J Emerg Med JT - The American journal of emergency medicine JID - 8309942 SB - IM MH - Adult MH - Aged MH - *Emergency Service, Hospital MH - Female MH - Humans MH - Iran MH - Male MH - Middle Aged MH - *Minimal Clinically Important Difference MH - Pain Measurement/*methods MH - Prospective Studies MH - Visual Analog Scale OTO - NOTNLM OT - Minimal clinically important difference OT - Numeric rating scale OT - Pain measurement OT - Visual analog scale EDAT- 2019/11/21 06:00 MHDA- 2020/08/22 06:00 CRDT- 2019/11/21 06:00 PHST- 2019/09/08 00:00 [received] PHST- 2019/09/26 00:00 [revised] PHST- 2019/09/27 00:00 [accepted] PHST- 2019/11/21 06:00 [pubmed] PHST- 2020/08/22 06:00 [medline] PHST- 2019/11/21 06:00 [entrez] AID - S0735-6757(19)30638-2 [pii] AID - 10.1016/j.ajem.2019.158489 [doi] PST - ppublish SO - Am J Emerg Med. 2020 Aug;38(8):1641-1646. doi: 10.1016/j.ajem.2019.158489. Epub 2019 Nov 4.