PMID- 31746249
OWN - NLM
STAT- MEDLINE
DCOM- 20201028
LR  - 20201028
IS  - 1651-226X (Electronic)
IS  - 0284-186X (Linking)
VI  - 59
IP  - 2
DP  - 2020 Feb
TI  - IAEA methodology for on-site end-to-end IMRT/VMAT audits: an international pilot 
      study.
PG  - 141-148
LID - 10.1080/0284186X.2019.1685128 [doi]
AB  - Background: The IAEA has developed and tested an on-site, end-to-end IMRT/VMAT 
      dosimetry audit methodology for head and neck cases using an anthropomorphic 
      phantom. The audit methodology is described, and the results of the international 
      pilot testing are presented.Material and methods: The audit utilizes a specially 
      designed, commercially available anthropomorphic phantom capable of accommodating 
      a small volume ion chamber (IC) in four locations (three in planning target 
      volumes (PTVs) and one in an organ at risk (OAR)) and a Gafchromic film in a 
      coronal plane for the absorbed dose to water and two-dimensional dose 
      distribution measurements, respectively. The audit consists of a pre-visit and 
      on-site phases. The pre-visit phase is carried out remotely and includes a 
      treatment planning task and a set of computational exercises. The on-site phase 
      aims at comparing the treatment planning system (TPS) calculations with 
      measurements in the anthropomorphic phantom following an end-to-end approach. Two 
      main aspects were tested in the pilot study: feasibility of the planning 
      constraints and the accuracy of IC and film results in comparison with TPS 
      calculations. Treatment plan quality was scored from 0 to 100.Results: Forty-two 
      treatment plans were submitted by 14 institutions from 10 countries, with 79% of 
      them having a plan quality score over 90. Seventeen sets of IC measurement 
      results were collected, and the average measured to calculated dose ratio was 
      0.988 +/- 0.016 for PTVs and 1.020 +/- 0.029 for OAR. For 13 film measurement 
      results, the average gamma passing rate was 94.1% using criteria of 3%/3 mm, 20% 
      threshold and global gamma.Conclusions: The audit methodology was proved to be 
      feasible and ready to be adopted by national dosimetry audit networks for local 
      implementation.
FAU - Kazantsev, Pavel
AU  - Kazantsev P
AUID- ORCID: 0000-0001-7662-0992
AD  - International Atomic Energy Agency, Vienna, Austria.
FAU - Lechner, Wolfgang
AU  - Lechner W
AUID- ORCID: 0000-0001-9211-7510
AD  - Department of Radiation Oncology, Division of Medical Physics, Medical University 
      of Vienna, Vienna, Austria.
AD  - Christian Doppler Laboratory for Medical Radiation Research for Radiation 
      Oncology, Vienna, Austria.
FAU - Gershkevitsh, Eduard
AU  - Gershkevitsh E
AD  - North Estonia Medical Centre, Tallinn, Estonia.
FAU - Clark, Catharine H
AU  - Clark CH
AD  - Department of Medical Physics, Royal Surrey County Hospital, Guildford, UK.
AD  - Metrology for Medical Physics (MEMPHYS), National Physical Laboratory, 
      Teddington, UK.
FAU - Venencia, Daniel
AU  - Venencia D
AD  - Instituto Privado de Radioterapia, Cordoba, Argentina.
FAU - Van Dyk, Jacob
AU  - Van Dyk J
AUID- ORCID: 0000-0003-0304-2647
AD  - Department of Oncology and Medical Biophysics, Western University, London, 
      Canada.
FAU - Wesolowska, Paulina
AU  - Wesolowska P
AD  - International Atomic Energy Agency, Vienna, Austria.
FAU - Hernandez, Victor
AU  - Hernandez V
AUID- ORCID: 0000-0003-3770-8486
AD  - Department of Medical Physics, Hospital Sant Joan de Reus, IISPV, Tarragona, 
      Spain.
FAU - Jornet, Nuria
AU  - Jornet N
AD  - Servei de Radiofisica i Radioproteccio, Hospital de la Santa Creu i Sant Pau, 
      Barcelona, Spain.
FAU - Tomsej, Milan
AU  - Tomsej M
AD  - CHU Charleroi, Hopital Andre Vesale, Montigny-le-Tilleul, Belgium.
FAU - Bokulic, Tomislav
AU  - Bokulic T
AUID- ORCID: 0000-0003-3974-6662
AD  - International Atomic Energy Agency, Vienna, Austria.
FAU - Izewska, Joanna
AU  - Izewska J
AD  - International Atomic Energy Agency, Vienna, Austria.
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
DEP - 20191120
PL  - Sweden
TA  - Acta Oncol
JT  - Acta oncologica (Stockholm, Sweden)
JID - 8709065
SB  - IM
MH  - Feasibility Studies
MH  - Head and Neck Neoplasms/radiotherapy
MH  - Humans
MH  - International Agencies
MH  - Medical Audit/*methods/standards
MH  - Phantoms, Imaging
MH  - Pilot Projects
MH  - Quality Assurance, Health Care
MH  - Radiometry/instrumentation/*standards
MH  - Radiotherapy Dosage
MH  - Radiotherapy Planning, Computer-Assisted/*standards
MH  - Radiotherapy, Intensity-Modulated/*standards
EDAT- 2019/11/21 06:00
MHDA- 2020/10/29 06:00
CRDT- 2019/11/21 06:00
PHST- 2019/11/21 06:00 [pubmed]
PHST- 2020/10/29 06:00 [medline]
PHST- 2019/11/21 06:00 [entrez]
AID - 10.1080/0284186X.2019.1685128 [doi]
PST - ppublish
SO  - Acta Oncol. 2020 Feb;59(2):141-148. doi: 10.1080/0284186X.2019.1685128. Epub 2019 
      Nov 20.