PMID- 31749340
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201215
IS  - 2287-4208 (Print)
IS  - 2287-4690 (Electronic)
IS  - 2287-4208 (Linking)
VI  - 38
IP  - 2
DP  - 2020 Apr
TI  - Electromagnetic Low-Intensity Extracorporeal Shock Wave Therapy in Patients with 
      Erectile Dysfunction: A Sham-Controlled, Double-Blind, Randomized Prospective 
      Study.
PG  - 236-242
LID - 10.5534/wjmh.190130 [doi]
AB  - PURPOSE: The aim of the present study was to evaluate the efficacy and safety of 
      the electromagnetic-type low-intensity extracorporeal shock wave therapy 
      (Li-ESWT) in patients with erectile dysfunction (ED). MATERIALS AND METHODS: The 
      randomized, sham-controlled, double-blind prospective study was performed at two 
      referral hospitals. Participants were randomized in a 1:1 ratio to receive sham 
      or Li-ESWT for 6 weeks. ED was evaluated at screening and at 4 and 7 weeks after 
      treatment. Participants were asked to complete the international index of 
      erectile function-erectile function (IIEF-EF) domain questionnaire, erection 
      hardness scale (EHS), and sexual encounter profile questionnaire (SEPQ 2 and 3). 
      The development of complications was investigated. RESULTS: Eighty-one of 96 
      patients completed the study. The median change in the IIEF-EF score in the 
      Li-ESWT and sham groups was 5.1 and -2.2 (p<0.001), respectively, at the 7-week 
      follow-up; 47.4% (18/38) patients had EHS <3, of which 77.8% (14/18) showed 
      significant improvement in virtue of Li-ESWT treatment (p=0.001). A significant 
      improvement was observed in the percentage of "Yes" responses to SEPQ 2 and 3 in 
      the Li-ESWT group vs. sham group from baseline to 7-week follow-up (91.3% vs. 
      69.4%; p=0.008 and 50.0% vs. 14.3%; p=0.002, respectively). No patients reported 
      pain or other adverse events during treatment or follow-up. CONCLUSIONS: Thus, 
      Li-ESWT could have a role in improving erectile function. Furthermore, it is 
      safe. We believe that Li-ESWT is an attractive new treatment modality for 
      patients with ED.
CI  - Copyright (c) 2020 Korean Society for Sexual Medicine and Andrology.
FAU - Kim, Kang Sup
AU  - Kim KS
AUID- ORCID: 0000-0002-9534-7829
AD  - Department of Urology, Incheon St. Mary's Hospital, College of Medicine, The 
      Catholic University of Korea, Seoul, Korea.
FAU - Jeong, Hyun Cheol
AU  - Jeong HC
AUID- ORCID: 0000-0001-8846-1351
AD  - Department of Urology, Kangdong Sacred Heart Hospital, Hallym University College 
      of Medicine, Seoul, Korea.
FAU - Choi, Sae Woong
AU  - Choi SW
AUID- ORCID: 0000-0002-3829-939X
AD  - Department of Urology, Yeouido St. Mary's Hospital, College of Medicine, The 
      Catholic University of Korea, Seoul, Korea.
FAU - Choi, Yong Sun
AU  - Choi YS
AUID- ORCID: 0000-0003-2903-0812
AD  - Department of Urology, Eunpyeong St. Mary's Hospital, College of Medicine, The 
      Catholic University of Korea, Seoul, Korea.
FAU - Cho, Hyuk Jin
AU  - Cho HJ
AUID- ORCID: 0000-0003-2599-2950
AD  - Department of Urology, Seoul St. Mary's Hospital, College of Medicine, The 
      Catholic University of Korea, Seoul, Korea.
FAU - Ha, U Syn
AU  - Ha US
AUID- ORCID: 0000-0001-9930-0588
AD  - Department of Urology, Seoul St. Mary's Hospital, College of Medicine, The 
      Catholic University of Korea, Seoul, Korea.
FAU - Hong, Sung Hoo
AU  - Hong SH
AUID- ORCID: 0000-0002-1952-4010
AD  - Department of Urology, Seoul St. Mary's Hospital, College of Medicine, The 
      Catholic University of Korea, Seoul, Korea.
FAU - Lee, Ji Youl
AU  - Lee JY
AUID- ORCID: 0000-0001-6775-1157
AD  - Department of Urology, Seoul St. Mary's Hospital, College of Medicine, The 
      Catholic University of Korea, Seoul, Korea.
FAU - Lee, Seung Wook
AU  - Lee SW
AUID- ORCID: 0000-0002-4818-5847
AD  - Department of Urology, Hanyang University College of Medicine, Seoul, Korea.
FAU - Ahn, Sun Tae
AU  - Ahn ST
AUID- ORCID: 0000-0003-1233-5951
AD  - Department of Urology, Korea University College of Medicine, Seoul, Korea.
FAU - Moon, Du Geon
AU  - Moon DG
AUID- ORCID: 0000-0002-9031-9845
AD  - Department of Urology, Korea University College of Medicine, Seoul, Korea.
FAU - Bae, Woong Jin
AU  - Bae WJ
AUID- ORCID: 0000-0001-7703-1161
AD  - Department of Urology, Seoul St. Mary's Hospital, College of Medicine, The 
      Catholic University of Korea, Seoul, Korea.
AD  - Catholic Integrative Medicine Research Institute, College of Medicine, The 
      Catholic University of Korea, Seoul, Korea. bwoong@catholic.ac.kr.
FAU - Kim, Sae Woong
AU  - Kim SW
AUID- ORCID: 0000-0002-9127-9400
AD  - Department of Urology, Seoul St. Mary's Hospital, College of Medicine, The 
      Catholic University of Korea, Seoul, Korea.
AD  - Catholic Integrative Medicine Research Institute, College of Medicine, The 
      Catholic University of Korea, Seoul, Korea. ksw1227@catholic.ac.kr.
LA  - eng
GR  - HI17C1944/Korea Health Industry Development Institute/Republic of Korea
GR  - HI17C1944/MHW/Ministry of Health and Welfare/Korea
PT  - Journal Article
DEP - 20191119
PL  - Korea (South)
TA  - World J Mens Health
JT  - The world journal of men's health
JID - 101596899
CIN - Eur Urol. 2020 Jul;78(1):110-111. PMID: 32127212
CIN - J Urol. 2020 Jun;203(6):1045. PMID: 32186454
PMC - PMC7076310
OTO - NOTNLM
OT  - Electromagnetic
OT  - Erectile dysfunction
OT  - Humans
OT  - Low-intensity extracorporeal shock wave therapy
COIS- The authors have nothing to disclose.
EDAT- 2019/11/22 06:00
MHDA- 2019/11/22 06:01
PMCR- 2020/04/01
CRDT- 2019/11/22 06:00
PHST- 2019/09/26 00:00 [received]
PHST- 2019/10/31 00:00 [revised]
PHST- 2019/10/31 00:00 [accepted]
PHST- 2019/11/22 06:00 [pubmed]
PHST- 2019/11/22 06:01 [medline]
PHST- 2019/11/22 06:00 [entrez]
PHST- 2020/04/01 00:00 [pmc-release]
AID - 37.e59 [pii]
AID - 10.5534/wjmh.190130 [doi]
PST - ppublish
SO  - World J Mens Health. 2020 Apr;38(2):236-242. doi: 10.5534/wjmh.190130. Epub 2019 
      Nov 19.