PMID- 31750102
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201201
IS  - 2231-3796 (Print)
IS  - 0973-7707 (Electronic)
IS  - 2231-3796 (Linking)
VI  - 71
IP  - 4
DP  - 2019 Dec
TI  - Isovolumetric Relaxation Time (IVRT): An Effective Tool in Management of 
      Subclinical Hypothyroidism.
PG  - 449-452
LID - 10.1007/s12070-019-01615-z [doi]
AB  - Hypothyroidism is a common condition in which thyroid gland doesn't produce 
      sufficient thyroid hormone. Normal range of TSH is 0.4 to 4 mIU/L. Patients with 
      TSH between 5 and 10 mIU/L, with normal T(4) are diagnosed to have subclinical 
      hypothyroidism. Decision to treat, particularly the subclinical hypothyroidism is 
      tailored to individual patients. In our study, isovolumetric relaxation time 
      (IVRT) was used to detect the diastolic function of cardia in hypothyroid 
      patient, with the help of 2D echocardiogram. Normal duration of IVRT is 54 to 
      65 mus and in hypothyroidism it is expected to increase. To assess, whether IVRT 
      is an effective tool in the management of subclinical hypothyroidism. 50 patients 
      attending otorhinolaryngology OPD with TSH level of 5 to 10 mIU/L were selected 
      for the study. All these were sent for 2D echocardiogram, for the measurement of 
      IVRT. These 50 patients were divided into 2 groups. Group A-patients with TSH 
      level 5 to 10 mIU/L and normal IVRT. Group B-patients with TSH level 5 to 10 
      mIU/L and prolonged IVRT. Patients in Group A were not given thyroxine, and after 
      3 months, they were reviewed with TSH level and IVRT duration. Patients in Group 
      B were started with thyroxine, and after 3 months, they were reviewed with TSH 
      level and IVRT duration. The basal and 3 months follow up values of TSH and IVRT 
      was analysed on both the groups. The p value of group A was not significant, but 
      p value group B was significant. IVRT as a measuring tool in sub clinical 
      hypothyroidism will definitely bring a major change in the concepts of treatment.
CI  - (c) Association of Otolaryngologists of India 2019.
FAU - Jyothi Prakash, Gaddada Devara Mutt Basavaraj
AU  - Jyothi Prakash GDMB
AD  - Department of Emergency Medicine, SS Institute of Medical Science, Davangere, 
      Karnataka India.
FAU - Santosh, Uttarkar Pandurangarao
AU  - Santosh UP
AD  - 2Department of ENT, JJM Medical College, Davangere, Karnataka India. GRID: 
      grid.418280.7. ISNI: 0000 0004 1794 3160
FAU - Sridurga, Janarthanan
AU  - Sridurga J
AD  - 2Department of ENT, JJM Medical College, Davangere, Karnataka India. GRID: 
      grid.418280.7. ISNI: 0000 0004 1794 3160
LA  - eng
PT  - Journal Article
DEP - 20190207
PL  - India
TA  - Indian J Otolaryngol Head Neck Surg
JT  - Indian journal of otolaryngology and head and neck surgery : official publication 
      of the Association of Otolaryngologists of India
JID - 9422551
PMC - PMC6838295
OTO - NOTNLM
OT  - 2D echocardiogram
OT  - IVRT
OT  - Subclinical hypothyroidism
OT  - Thyroxine
COIS- Conflict of interestNone.
EDAT- 2019/11/22 06:00
MHDA- 2019/11/22 06:01
PMCR- 2020/12/01
CRDT- 2019/11/22 06:00
PHST- 2019/01/03 00:00 [received]
PHST- 2019/01/31 00:00 [accepted]
PHST- 2019/11/22 06:00 [entrez]
PHST- 2019/11/22 06:00 [pubmed]
PHST- 2019/11/22 06:01 [medline]
PHST- 2020/12/01 00:00 [pmc-release]
AID - 1615 [pii]
AID - 10.1007/s12070-019-01615-z [doi]
PST - ppublish
SO  - Indian J Otolaryngol Head Neck Surg. 2019 Dec;71(4):449-452. doi: 
      10.1007/s12070-019-01615-z. Epub 2019 Feb 7.